Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Charles W Emala"'
Autor:
Huachao Huang, Yinshan Fang, Ming Jiang, Yihan Zhang, Jana Biermann, Johannes C Melms, Jennifer A Danielsson, Ying Yang, Li Qiang, Jia Liu, Yiwu Zhou, Manli Wang, Zhihong Hu, Timothy C Wang, Anjali Saqi, Jie Sun, Ichiro Matsumoto, Wellington V Cardoso, Charles W Emala, Jian Zhu, Benjamin Izar, Hongmei Mou, Jianwen Que
Publikováno v:
eLife, Vol 11 (2022)
Viral infection often causes severe damage to the lungs, leading to the appearance of ectopic basal cells (EBCs) and tuft cells in the lung parenchyma. Thus far, the roles of these ectopic epithelial cells in alveolar regeneration remain controversia
Externí odkaz:
https://doaj.org/article/a89690d63c0b4788974d3765d808f613
Autor:
Robert A Whittington, László Virág, François Marcouiller, Marie-Amélie Papon, Noura B El Khoury, Carl Julien, Françoise Morin, Charles W Emala, Emmanuel Planel
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16648 (2011)
In Alzheimer's disease (AD) and other tauopathies, the microtubule-associated protein tau can undergo aberrant hyperphosphorylation potentially leading to the development of neurofibrillary pathology. Anesthetics have been previously shown to induce
Externí odkaz:
https://doaj.org/article/0c7d8386492b4f27ad2f45afedde8f4b
Publikováno v:
Japanese Dental Science Review, Vol 55, Iss 1, Pp 103-107 (2019)
Obesity is a major risk factor for the development of asthma, and worsens the key features of asthma including airway hyperresponsiveness, inflammation, and airway remodeling. Although pro- and anti-inflammatory adipocytokines may contribute to the p
Externí odkaz:
https://doaj.org/article/5263f2d30f1247e3a8206f2547d9c506
Autor:
Jose F, Perez-Zoghbi, Dannah Rae, Sajorda, Daniel A, Webb, Leggy A, Arnold, Charles W, Emala, Gene T, Yocum
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 67:482-490
Asthma is a common respiratory disease characterized, in part, by excessive airway smooth muscle (ASM) contraction (airway hyperresponsiveness). Various GABA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a371b2a3936bdd4512baccfca344ba0
https://doi.org/10.1165/rcmb.2022-0084oc
https://doi.org/10.1165/rcmb.2022-0084oc
Autor:
Shuwei Zhang, Emily DiMango, Yingdong Zhu, Tarnjot K. Saroya, Charles W. Emala, Shengmin Sang
Publikováno v:
Journal of Agricultural and Food Chemistry. 70:9674-9683
6-Gingerol and 6-shogaol are the most abundant gingerols and shogaols in ginger root and have been shown to reduce the asthmatic phenotype in murine models of asthma. Several studies have described the pharmacokinetics of gingerols and shogaols in hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce34c78959c10d9be9d2501a4bd9239
https://doi.org/10.1021/acs.jafc.2c03150
https://doi.org/10.1021/acs.jafc.2c03150
Autor:
M. S. Rashid Roni, Nicolas M. Zahn, Gene T. Yocum, Daniel A. Webb, Md Yeunus Mian, Michelle J. Meyer, Anika S. Tylek, James M. Cook, Charles W. Emala, Douglas C. Stafford, Leggy A. Arnold
Publikováno v:
Drug Dev Res
MIDD0301 is being developed as an oral drug to relax airway smooth muscle and reduce lung inflammation in asthma. We report a comparative study of MIDD0301 and its S isomer (MIDD0301S) and found that the compounds have equivalent affinity for GABA(A)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40aeb95cbea0d6d642fc7cfe1230d732
https://doi.org/10.1002/ddr.21926
https://doi.org/10.1002/ddr.21926
Autor:
Nicolas M. Zahn, M. S. Rashid Roni, Gene T. Yocum, Michelle J. Meyer, Daniel A. Webb, Md Yeunus Mian, James M. Cook, Douglas C. Stafford, Charles W. Emala, Leggy A. Arnold
Publikováno v:
ACS Pharmacology & Translational Science. 5:80-88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c51d0f6fe72762c3b66bec25f008718
https://doi.org/10.1021/acsptsci.1c00238
https://doi.org/10.1021/acsptsci.1c00238
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 321:L991-L1005
Nocturnal asthma is characterized by heightened bronchial reactivity at night, and plasma melatonin concentrations are higher in patients with nocturnal asthma symptoms. Numerous physiological effects of melatonin are mediated via its specific G prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c46513b316f4a2e15da183bde95938c
https://doi.org/10.1152/ajplung.00273.2021
https://doi.org/10.1152/ajplung.00273.2021
Autor:
Huachao Huang, Yinshan Fang, Ming Jiang, Yihan Zhang, Jana Biermann, Johannes C Melms, Jennifer A Danielsson, Ying Yang, Li Qiang, Jia Liu, Yiwu Zhou, Manli Wang, Zhihong Hu, Timothy C Wang, Anjali Saqi, Jie Sun, Ichiro Matsumoto, Wellington V Cardoso, Charles W Emala, Jian Zhu, Benjamin Izar, Hongmei Mou, Jianwen Que
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f9e8924dea244780b75bb249b54781d
https://doi.org/10.7554/elife.78217.sa2
https://doi.org/10.7554/elife.78217.sa2
Autor:
Elvedin Lukovic, Charles W. Emala
Publikováno v:
Am J Respir Cell Mol Biol
Exaggerated airway smooth muscle (ASM) contraction regulated by the Gq family of G protein-coupled receptors causes airway hyperresponsiveness in asthma. Activation of Gq-coupled G protein-coupled receptors leads to phospholipase C (PLC)-mediated gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d144112ec3d32ebfa3d714565129df
https://doi.org/10.1165/rcmb.2021-0325ed
https://doi.org/10.1165/rcmb.2021-0325ed