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pro vyhledávání: '"Charles W, Daniel"'
Publikováno v:
Journal of Mammary Gland Biology and Neoplasia. 14:355-362
Autor:
Phyllis Strickland, Charles W. Daniel, Michael T. Lewis, Sarajane Ross, Elsa Jimenez, Chi-chung Hui, Charles W. Sugnet
Publikováno v:
Developmental Biology, vol 238, iss 1
The hedgehog signal transduction network performs critical roles in mediating cell-cell interactions during embryogenesis and organogenesis. Loss-of-function or misexpression mutation of hedgehog network components can cause birth defects, skin cance
Autor:
Charles W. Daniel, Gilbert H. Smith
Publikováno v:
Journal of Mammary Gland Biology and Neoplasia. 4:3-8
Publikováno v:
Journal of Cellular Biochemistry. 69:377-391
Homeobox-containing genes encode transcriptional regulators involved in cell fate and pattern formation during embryogenesis. Recently, it has become clear that their expression in continuously developing adult tissues, as well as in tumorigenesis, m
Autor:
Charles W. Daniel, Phyllis Strickland, Gary B. Silberstein, Katharine Van Horn, Charles T. Roberts
Publikováno v:
Proceedings of the National Academy of Sciences. 94:8132-8137
The product of the WT1 Wilms tumor suppressor gene controls the expression of genes encoding components of the insulin-like growth factor and transforming growth factor β signaling systems. The role of these growth factors in breast tumor growth led
Publikováno v:
Endocrinology. 134:84-90
The mammogenic actions of estrogen, although undisputed, lack definition due to uncertainties concerning the relative importance of systemic vs. local actions of the hormone. In addition to its well known, indirect effects on mammary tissue through p
Publikováno v:
The Journal of Cell Biology
Mammary explants from 14-15-d-pregnant mice synthesize and secrete milk proteins in culture in response to insulin, hydrocortisone, and prolactin. Here we demonstrate that transforming growth factor beta (TGF beta) treatment suppresses, in a dose dep
Publikováno v:
Developmental Biology. 152:354-362
Branching morphogenesis in the mammary gland involves focal regions of cell proliferation, the terminal and lateral ductal buds, that exist simultaneously with extensive regions of differentiated ducts in which budding and growth are actively suppres
Autor:
Charles W. Daniel, Stephen Robinson
Publikováno v:
Molecular Reproduction and Development. 32:145-151
We have previously shown that TGF-beta 1 rapidly and reversibly inhibits ductal growth in vivo when administered by miniature slow-release plastic implants. A possible role for endogenous TGF-beta 1 was suggested by the observation that the normal gl
Publikováno v:
Journal of mammary gland biology and neoplasia. 14(3)