Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Charles Vargas-Lopes"'
Autor:
Caroline Madeira, Flavio V. Alheira, Marilia A. Calcia, Thuany C. S. Silva, Filippe M. Tannos, Charles Vargas-Lopes, Melissa Fisher, Nelson Goldenstein, Marco Antonio Brasil, Sophia Vinogradov, Sergio T. Ferreira, Rogerio Panizzutti
Publikováno v:
Frontiers in Psychiatry, Vol 9 (2018)
Converging evidence indicates that dysfunctions in glutamatergic neurotransmission and in the glutamate-glutamine cycle play a role in the pathophysiology of schizophrenia. Here, we investigated glutamate and glutamine levels in the blood of patients
Externí odkaz:
https://doaj.org/article/ac02bce32c8444b5901a26c4b47c13f8
Autor:
Caroline Madeira, Charles Vargas-Lopes, Carlos Otávio Brandão, Taylor Reis, Jerson Laks, Rogerio Panizzutti, Sergio T. Ferreira
Publikováno v:
Frontiers in Psychiatry, Vol 9 (2018)
Recent evidence suggests that Alzheimer's disease (AD) and depression share common mechanisms of pathogenesis. In particular, deregulation of glutamate-mediated excitatory signaling may play a role in brain dysfunction in both AD and depression. We h
Externí odkaz:
https://doaj.org/article/a1cf07c42eb34b3f8e3a27e2ec0889bb
Autor:
Charles Vargas-Lopes, Pedro Kurtz, Caroline Madeira, Fernando A. Bozza, Luciano Cesar Pontes Azevedo, Darwin Prado, Rogerio Panizzutti, Joana C. D’Avila
Publikováno v:
Shock. 51:228-234
Acute brain dysfunction is a complication of sepsis, and its pathophysiology remains poorly understood. We studied the brain metabolism in a resuscitated animal model of sepsis. Twelve anesthetized, mechanically ventilated, and invasively monitored p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7f40de8e762e1b9c617818b80f6756
https://doi.org/10.1097/shk.0000000000001138
https://doi.org/10.1097/shk.0000000000001138
Autor:
Alex C. Manhães, Charles Vargas-Lopes, Marcos Avellar, Caroline Madeira, Rogerio Panizzutti, Camila Dantas, Linda Scoriels, Homero Leite, Priscila Nascimento Marques
Publikováno v:
Oncotarget
// Marcos Avellar 1,2,* , Linda Scoriels 1,2,3,* , Caroline Madeira 1 , Charles Vargas-Lopes 1 , Priscila Marques 1 , Camila Dantas 1 , Alex C. Manhaes 4 , Homero Leite 5 and Rogerio Panizzutti 1,2 1 Biomedical Sciences Institute, Federal University
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd893c8f5dacc3693bc53fb816de7605
https://doi.org/10.18632/oncotarget.7691
https://doi.org/10.18632/oncotarget.7691
Autor:
Marilia A. Calcia, Sergio T. Ferreira, Caroline Madeira, Flávio Valdozende Alheira, Charles Vargas-Lopes, Marco Antonio Alves Brasil, Nelson Goldenstein, Thuany Cristine Santos da Silva, Rogerio Panizzutti, Filippe M. Tannos
Publikováno v:
Schizophrenia Research. 142:83-87
Changes in D-serine availability in the brain may contribute to the hypofunction of NMDA-glutamate receptors in schizophrenia; however, measurements of blood levels of D-serine in individuals with schizophrenia have not been consistent amongst previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568c4fce19fbf97fe2e96e874a5d336e
https://doi.org/10.1016/j.schres.2012.09.014
https://doi.org/10.1016/j.schres.2012.09.014
Autor:
Pedro Setti-Perdigão, Soniza Vieira Alves-Leon, Jorge Marcondes de Souza, Flávia Carvalho Alcantara Gomes, Newton G. Castro, Rogerio Panizzutti, Suzana Assad Kahn, Joari De Miranda, Vanessa Tortelli, Joice Stipursky, Luan Pereira Diniz, Juliana Carvalho Almeida, Charles Vargas Lopes, Luciana Romão
Publikováno v:
The Journal of Biological Chemistry
Background: Synapse formation and function is modulated by intrinsic and extrinsic non-autonomous factors. Results: Astrocytes induce synapse formation through TGF-β1 pathway. TGF-β1 synaptogenic property is dependent on d-serine signaling. Conclus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1521fe3b72657a67edfa0b86c90ace92
https://doi.org/10.1074/jbc.m112.380824
https://doi.org/10.1074/jbc.m112.380824
Autor:
Rogerio Panizzutti, Suzana Assad Kahn, Jean-Christophe Houzel, Charles Vargas-Lopes, Marta S. De Freitas, Caroline Madeira, Sergio T. Ferreira, Joari De Miranda, Patricia Bado, Ingrid Albino do Couto
Publikováno v:
Journal of Neurochemistry. 116:281-290
D-serine is a co-agonist of NMDA receptor (NMDAR) and plays important roles in synaptic plasticity mechanisms. Serine racemase (SR) is a brain-enriched enzyme that converts L-serine to D-serine. SR interacts with the protein interacting with C-kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3cf23e6af3feac1e5573c2d85777ac9
https://doi.org/10.1111/j.1471-4159.2010.07102.x
https://doi.org/10.1111/j.1471-4159.2010.07102.x
Autor:
Rogerio Panizzutti, Maria Eliza T. Freitas, Herman Wolosker, Caroline Madeira, Charles Vargas-Lopes
Publikováno v:
Schizophrenia Research. 101:76-83
D-serine has been shown to be a major endogenous coagonist of the N-methyl D-aspartate (NMDA) type of glutamate receptors. Accumulating evidence suggests that NMDA receptor hypofunction contributes to the symptomatic features of schizophrenia. d-seri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3013a7a120d5f8be3c94fbc6fd63b57d
https://doi.org/10.1016/j.schres.2008.02.002
https://doi.org/10.1016/j.schres.2008.02.002
Autor:
Mychael V. Lourenco, Caroline Madeira, Taylor Reis, Carlos Augusto Pasqualucci, Lea T. Grinberg, Rogerio Panizzutti, Carlos Otávio Brandão, Claudia K. Suemoto, Renata Elaine Paraizo Leite, Jerson Laks, Sergio T. Ferreira, Wilson Jacob-Filho, Charles Vargas-Lopes
Publikováno v:
Translational psychiatry, vol 5, iss 5
Translational Psychiatry
ResearcherID
Madeira, C; Lourenco, MV; Vargas-Lopes, C; Suemoto, CK; Brandão, CO; Reis, T; et al.(2015). D-serine levels in Alzheimer's disease: Implications for novel biomarker development. Translational Psychiatry, 5. doi: 10.1038/tp.2015.52. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7qs6w6pb
Translational Psychiatry
ResearcherID
Madeira, C; Lourenco, MV; Vargas-Lopes, C; Suemoto, CK; Brandão, CO; Reis, T; et al.(2015). D-serine levels in Alzheimer's disease: Implications for novel biomarker development. Translational Psychiatry, 5. doi: 10.1038/tp.2015.52. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7qs6w6pb
Alzheimer's disease (AD) is a severe neurodegenerative disorder still in search of effective methods of diagnosis. Altered levels of the NMDA receptor co-agonist, d-serine, have been associated with neurological disorders, including schizophrenia and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff507ab75b5f5f832faeb0e03b7c1e0
https://escholarship.org/uc/item/7qs6w6pb
https://escholarship.org/uc/item/7qs6w6pb
Autor:
Charles Vargas-Lopes, Rogerio Panizzutti, Joana C. D’Avila, Gerson D. Guercio, A. Oliveira, L.E. Bevictori, Caroline Madeira, V.F. Carvalho
Publikováno v:
Neuropharmacology. 86
Increasing evidence indicates that acute stress disrupts cognitive functions mediated by glutamate-NMDA receptors, although the mechanisms are not fully understood. Here we investigated whether d-serine and glycine, the endogenous co-agonists of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e148102749becf251d232b999e5a2274
https://pubmed.ncbi.nlm.nih.gov/24978104
https://pubmed.ncbi.nlm.nih.gov/24978104