Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Charles T.R. Heffern"'
Autor:
Javier L. Baylon, Emad Tajkhorshid, Charles T.R. Heffern, Zhiliang Gong, Mark L. Schlossman, Erin J. Adams, J. Michael Henderson, Mati Meron, Binhua Lin, Ka Yee C. Lee, Daniel Kerr, Gregory T. Tietjen
Publikováno v:
Biophysical journal. 113(7)
The dynamic nature of lipid membranes presents significant challenges with respect to understanding the molecular basis of protein/membrane interactions. Consequently, there is relatively little known about the structural mechanisms by which membrane
Autor:
Luka Pocivavsek, Ka Yee C. Lee, Konstantin G. Birukov, Charles T.R. Heffern, Anna A. Birukova, Nurgul Moldobaeva, Valery N. Bochkov
Publikováno v:
Chemistry and Physics of Lipids. :9-19
The lipid membrane not only provides a rich interface with an array of receptor signaling complexes with which a cell communicates, but it also serves as a source of lipid derived bioactive molecules. In pathologic conditions of acute lung injury (AL
Autor:
Wei Bu, Siheng Sean You, Yeling Dai, Charles T.R. Heffern, Ka Yee C. Lee, J. Michael Henderson, Wenyi Xie, Mati Meron, Binhua Lin
Publikováno v:
The journal of physical chemistry. B. 120(34)
Amphiphilic phospholipids and nanoparticles functionalized with hydrophobic capping ligands have previously been extensively investigated for their capacity to self-assemble into Langmuir monolayers at the air/water interface. However, understanding
Autor:
Jaroslaw Majewski, Bulent Akgun, Charles T.R. Heffern, J. Michael Henderson, Ginevra A. Clark, Ka Yee C. Lee
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 31(46)
We found that interactions of dipalmitoylphosphatidylcholine (DPPC) lipid monolayers with sugars are influenced by addition of NaCl. This work is of general importance in understanding how sugar-lipid-salt interactions impact biological systems. Usin
Autor:
Chiu Hao Chen, Mark L. Schlossman, James E. Crooks, Theodore L. Steck, Gregory T. Tietjen, Charles T.R. Heffern, Ka Yee C. Lee, Benoît Roux, Binhua Lin, Kathleen D. Cao, Zhiliang Gong, Erin J. Adams, J. Michael Henderson, Ernesto Vargas, Mati Meron
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 111(15)
Recognition of phosphatidylserine (PS) lipids exposed on the extracellular leaflet of plasma membranes is implicated in both apoptotic cell removal and immune regulation. The PS receptor T cell immunoglobulin and mucin-domain-containing molecule 4 (T
Autor:
Zhiliang L. Gong, Kathleen D. Cao, Sushil K. Satija, Nishanth S. Iyengar, Gregory T. Tietjen, Jaroslaw Majewski, Binhua Lin, Alan J. Waring, Charles T.R. Heffern, J. Michael Henderson, Indroneil Roy, Mati Meron, Daniel Kerr, Ka Yee C. Lee
Publikováno v:
Biophysical Journal. 108:550a-551a
The ability of antimicrobial peptides (AMPs) to target and lyse the harmful microbial membrane over that of a host's is a unique characteristic, making these innate immune effectors promising candidates to fill a growing therapeutic void resulting fr
Autor:
Gregory T. Tietjen, Mark L. Schlossman, James E. Crooks, Kathleen D. Cao, Benoît Roux, Binhua Lin, Charles T.R. Heffern, Ernesto Vargas, Ka Yee C. Lee, Erin J. Adams, Mati Meron, Chiu-Hao Chen
Publikováno v:
Biophysical Journal. 104(2)
The immune system recognizes a vast array of chemical signatures as antigens although historically most research has focused more exclusively on protein/protein recognition. More recently it has been appreciated that lipid membranes can also provide
Autor:
Daniel Kerr, Mark L. Schlossman, Greg T. Tietjen, Charles T.R. Heffern, Ka Yee C. Lee, Simon Chu, Erin J. Adams, J. Michael Henderson, Binhua Lin, Mati Meron, Zhiliang Gong
Publikováno v:
Biophysical Journal. 110:254a
While molecular structures are available for many proteins, rarely is a structure determined in a protein's functional context. For proteins that bind with lipid membranes, traditional structural methods cannot probe the protein-membrane complex. X-r
Autor:
Ka Yee C. Lee, Charles T.R. Heffern, Benoît Roux, Ernesto Vargas, Kathleen D. Cao, Mark L. Schlossman, Theordore L. Steck, James E. Crooks, Binhua Lin, Erin J. Adams, J. Michael Henderson, Gregory T. Tietjen, Mati Meron, Chiu-Hao Chen, Zhiliang Gong
Publikováno v:
Biophysical Journal. (2):17a
Recognition of phosphatidylserine (PS) lipids exposed on cell surfaces is implicated in both apoptotic cell removal and immune regulation. The PS receptor Tim4 is believed to regulate T cell immunity via phagocystosis of both apoptotic (high PS expos