Depletion of essential fatty acids in muscle is associated with shorter survival of cancer patients undergoing surgery-preliminary report

Autor: Amritpal S. Bhullar, Irma Magaly Rivas-Serna, Ana Anoveros-Barrera, Abha Dunichand-Hoedl, David Bigam, Rachel G. Khadaroo, Todd McMullen, Oliver Bathe, Charles T. Putman, Vickie Baracos, Michael T. Clandinin, Vera C. Mazurak

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)

Abstract Emerging studies are reporting associations between skeletal muscle abnormalities and survival in cancer patients. Cancer prognosis is associated with depletion of essential fatty acids in erythrocytes and plasma in humans. However the relat

Externí odkaz: https://doaj.org/article/383b0da5f06f447e92053de802692a2e

Clinical and biological characterization of skeletal muscle tissue biopsies of surgical cancer patients

Autor: Ana Anoveros‐Barrera, Amritpal S. Bhullar, Cynthia Stretch, Nina Esfandiari, Abha R. Dunichand‐Hoedl, Karen J.B. Martins, David Bigam, Rachel G. Khadaroo, Todd McMullen, Oliver F. Bathe, Sambasivarao Damaraju, Richard J. Skipworth, Charles T. Putman, Vickie E. Baracos, Vera C. Mazurak

Publikováno v: Journal of Cachexia, Sarcopenia and Muscle, Vol 10, Iss 6, Pp 1356-1377 (2019)

Abstract Background Researchers increasingly use intraoperative muscle biopsy to investigate mechanisms of skeletal muscle atrophy in patients with cancer. Muscles have been assessed for morphological, cellular, and biochemical features. The aim of t

Externí odkaz: https://doaj.org/article/5ee04632c532410fb52c9d5e4b608337

Potential Role of Omega-3 Fatty Acids on the Myogenic Program of Satellite Cells

Autor: Amritpal S. Bhullar, Charles T. Putman, Vera C. Mazurak

Publikováno v: Nutrition and Metabolic Insights, Vol 2016, Iss 9, Pp 1-10 (2016)

Externí odkaz: https://doaj.org/article/4fa49321509f4f1a868f63127267fe1f

Clinical and biological characterization of skeletal muscle tissue biopsies of surgical cancer patients

Autor: Vickie E. Baracos, Nina Esfandiari, Abha R. Dunichand-Hoedl, Amritpal S. Bhullar, Rachel G. Khadaroo, David L. Bigam, Ana Anoveros-Barrera, Karen J. B. Martins, Oliver F. Bathe, Todd McMullen, Richard J E Skipworth, Cynthia Stretch, Vera C. Mazurak, Charles T. Putman, Sambasivarao Damaraju

Publikováno v: Anoveros-Barrera, A, Bhullar, A S, Stretch, C, Esfandiari, N, Dunichand-Hoedl, A R, Martins, K J B, Bigam, D, Khadaroo, R G, McMullen, T, Bathe, O F, Damaraju, S, Skipworth, R J, Putman, C T, Baracos, V E & Mazurak, V C 2019, ' Clinical and biological characterization of skeletal muscle tissue biopsies of surgical cancer patients ', Journal of Cachexia, Sarcopenia and Muscle . https://doi.org/10.1002/jcsm.12466
Journal of Cachexia, Sarcopenia and Muscle, Vol 10, Iss 6, Pp 1356-1377 (2019)

BACKGROUND: Researchers increasingly use intraoperative muscle biopsy to investigate mechanisms of skeletal muscle atrophy in patients with cancer. Muscles have been assessed for morphological, cellular, and biochemical features. The aim of this stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c77e6cb2df0898ca72dabdb18d5f663
https://doi.org/10.1002/jcsm.12466

Multitargeted kinase inhibitors imatinib, sorafenib and sunitinib perturb energy metabolism and cause cytotoxicity to cultured C2C12 skeletal muscle derived myotubes

Autor: Michael B. Sawyer, Carol E. Cass, Vijaya L. Damaraju, Charles T. Putman, Michelle Kuzma

Publikováno v: Biochemical Pharmacology. 155:162-171

Tyrosine kinase inhibitors (TKIs) have advanced cancer treatment and prognosis but have also resulted in adverse effects such as fatigue, diarrhea, hypothyroidism, and other toxicities. We investigated TKI effects on skeletal muscle as a possible exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d76bafe7363028facba2acb584107d5
https://doi.org/10.1016/j.bcp.2018.07.001