Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Charles T, Benson"'
Autor:
Tamer Coskun, Kyle W. Sloop, Corina Loghin, Jorge Alsina-Fernandez, Shweta Urva, Krister B. Bokvist, Xuewei Cui, Daniel A. Briere, Over Cabrera, William C. Roell, Uma Kuchibhotla, Julie S. Moyers, Charles T. Benson, Ruth E. Gimeno, David A. D'Alessio, Axel Haupt
Publikováno v:
Molecular Metabolism, Vol 18, Iss , Pp 3-14 (2018)
Objective: A novel dual GIP and GLP-1 receptor agonist, LY3298176, was developed to determine whether the metabolic action of GIP adds to the established clinical benefits of selective GLP-1 receptor agonists in type 2 diabetes mellitus (T2DM). Metho
Externí odkaz:
https://doaj.org/article/e80aeca8145a4ac5b361969b75b1dc5e
Autor:
Shweta, Urva, Tamer, Coskun, Mei Teng, Loh, Yu, Du, Melissa K, Thomas, Sirel, Gurbuz, Axel, Haupt, Charles T, Benson, Martha, Hernandez-Illas, David A, D'Alessio, Zvonko, Milicevic
Publikováno v:
The Lancet. 400:1869-1881
Treating hyperglycaemia and obesity in individuals with type 2 diabetes using multi-receptor agonists can improve short-term and long-term outcomes. LY3437943 is a single peptide with agonist activity for glucagon, glucose-dependent insulinotropic po
Novel GIP/GLP-1/Glucagon Receptor Agonist LY3437943: A First in Human Dose Study in Healthy Subjects
Autor:
Shweta Urva, Yu Du, Melissa K Thomas, Zvonko Milicevic, Tamer Coskun, Charles T Benson, Corina Loghin, Nanette Schloot
Publikováno v:
Hand in Hand zum Ziel – einfach.besser.messbar www.diabeteskongress.de.
Autor:
Jan Willem van der Laan, Charles T. Benson, Walter Janssens, Jeroen Bos, Elke Stahl, Joseph T. Brady, Ulla Wändel-Liminga, Solange Corriol-Rohou, Roy Forster, Andreas Hartmann, Peter Einar Pertel, Sarah M. Robertson, Beatriz Silva-Lima, Raleigh E. Malik, Salah-Dine Chibout
Publikováno v:
Therapeutic Innovation & Regulatory Science. :216847901984351
Publikováno v:
Cryobiology. 32:493-502
Coupled with the rapid development of clinical pancreatic islet transplantation, there is an increasing requirement for cryopreservation of viable islets. Fundamental cryobiology requires determination of several cryobiophysical parameters to predict
Autor:
Elizabeth S. Critser, Dayong Gao, Gregory M. Preston, Charles T. Benson, John K. Critser, Chi Liu, Locksley E. McGann
Publikováno v:
Biology of Reproduction. 52:913-919
A novel integral membrane protein with an apparent molecular mass of 25 kDa (CHIP28) was first isolated from human erythrocytes and is now recognized as a water channel protein. The expression of this protein has been found in several other cell type
Publikováno v:
Cell Transplantation, Vol 2 (1993)
The ability to store pancreatic islets using cryopreservation methodology would greatly assist the application of clinical islet transplantation to Type 1 (insulin-dependent) diabetics. It is our working thesis that the illumination of fundamental bi
Publikováno v:
Biophysical journal. 71(1)
A novel microperfusion chamber was developed to measure kinetic cell volume changes under various extracellular conditions and to quantitatively determine cell membrane transport properties. This device eliminates modeling ambiguities and limitations
Publikováno v:
Journal of reproduction and fertility. 102(2)
A perfusion technique using micropipette methodology was developed to determine quantitatively the membrane transport properties of mammalian oocytes. This method eliminates modelling ambiguities inherent in microdiffusion, a closely related technolo
Autor:
Charles T. Benson, John K. Critser
Publikováno v:
Cryobiology. 31(3)
Oocytes provide an excellent model cell type for the exploration of the hypothesis that there is a genetic influence to inter-animal variability in plasma membrane water permeability (Lp) and its activation energy (Ea). Although variability among ooc