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of 3
pro vyhledávání: '"Charles Squires"'
Autor:
Michael T. Brewer, Tadahiko Kohno, Charles Squires, Phillip E. Schwartz, Susan L. Baker, James Vannice, Hale Karin K, Michael W. King, Robert C. Thompson
Publikováno v:
Proceedings of the National Academy of Sciences. 87:8331-8335
An inhibitor of tumor necrosis factor (TNF) has been isolated from the human histiocytic lymphoma cell line U-937 that is capable of inhibiting both TNF-alpha and TNF-beta. Protein sequencing has verified that it is distinct from a previously describ
Autor:
Thomas M. Gleason, Smith Christopher G, Tadahiko Kohno, Rebecca W Vanderslice, Susan L. Baker, Kathy K. Tucker, Charles Squires, Deborah A. Russell, Hale Karin K
Publikováno v:
Cytokine. 7(1)
Two soluble receptors of tumour necrosis factor were evaluated for development as potential therapeutic agents for inflammatory disease. The recombinant human soluble Type I and Type II TNF receptors, rsTNF-RI and rsTNF-RII, were expressed at high le
Autor:
David R. Clemmons, Walker H. Busby, Thompson Robert C, Michael T. Brewer, Charles Squires, Gary L. Stetler
Publikováno v:
Biochemical and biophysical research communications. 152(3)
Insulin-like growth factors (IGFs) bind to specific proteins present in extracellular fluids. One of these binding proteins (IGF-BP) was purified from human amniotic fluid and was shown to potentiate the effects of IGF-I in vitro (10). In these studi