Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Charles Schmitt"'
Autor:
José T. Moreira-Filho, Dhruv Ranganath, Mike Conway, Charles Schmitt, Nicole Kleinstreuer, Kamel Mansouri
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-27 (2024)
Abstract With the increased availability of chemical data in public databases, innovative techniques and algorithms have emerged for the analysis, exploration, visualization, and extraction of information from these data. One such technique is chemic
Externí odkaz:
https://doaj.org/article/4e06f021754148c3877a42c8c5c607f5
Autor:
Dawei Lin, Matthew McAuliffe, Kim D. Pruitt, Anupama Gururaj, Christine Melchior, Charles Schmitt, Susan N. Wright
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-14 (2024)
Abstract The demand for open data and open science is on the rise, fueled by expectations from the scientific community, calls to increase transparency and reproducibility in research findings, and developments such as the Final Data Management and S
Externí odkaz:
https://doaj.org/article/41b5efdd344d444cad5f1cc37f626e39
Autor:
Lauren E. Chan, Anne E. Thessen, William D. Duncan, Nicolas Matentzoglu, Charles Schmitt, Cynthia J. Grondin, Nicole Vasilevsky, Julie A. McMurry, Peter N. Robinson, Christopher J. Mungall, Melissa A. Haendel
Publikováno v:
Journal of Biomedical Semantics, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Background Evaluating the impact of environmental exposures on organism health is a key goal of modern biomedicine and is critically important in an age of greater pollution and chemicals in our environment. Environmental health utilizes man
Externí odkaz:
https://doaj.org/article/4d854f6d4a15453d96f678a86e9c0e6b
Corrigendum: Tox21Enricher-Shiny: an R Shiny application for toxicity functional annotation analysis
Autor:
Parker Combs, Jeremy Erickson, Jui-Hua Hsieh, Kai Guo, Sue Nolte, Charles Schmitt, Scott Auerbach, Junguk Hur
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
Externí odkaz:
https://doaj.org/article/230a2ee041984fc198b3d0cdd4b6ab9e
Autor:
Parker Combs, Jeremy Erickson, Jui-Hua Hsieh, Kai Guo, Sue Nolte, Charles Schmitt, Scott Auerbach, Junguk Hur
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
Inference of toxicological and mechanistic properties of untested chemicals through structural or biological similarity is a commonly employed approach for initial chemical characterization and hypothesis generation. We previously developed a web-bas
Externí odkaz:
https://doaj.org/article/eb9bf185c5fc46588c1f8a599061c2d9
Autor:
Karamarie Fecho, Chris Bizon, Frederick Miller, Shepherd Schurman, Charles Schmitt, William Xue, Kenneth Morton, Patrick Wang, Alexander Tropsha
Publikováno v:
JMIR Medical Informatics, Vol 9, Iss 7, p e26714 (2021)
BackgroundKnowledge graphs are a common form of knowledge representation in biomedicine and many other fields. We developed an open biomedical knowledge graph–based system termed Reasoning Over Biomedical Objects linked in Knowledge Oriented Pathwa
Externí odkaz:
https://doaj.org/article/87bef6324f9e46a591de5cb10e08de94
Publikováno v:
Informatics, Vol 2, Iss 3, Pp 20-30 (2015)
Genomics research presents technical, computational, and analytical challenges that are well recognized. Less recognized are the complex sociological, psychological, cultural, and political challenges that arise when genomics research takes place wit
Externí odkaz:
https://doaj.org/article/1dae8ae5636c4ed7bf21e13acfadef96
Autor:
Scott S. Auerbach, Nicole Kleinstreuer, Eugene N. Muratov, John P. Rooney, Charles Schmitt, Ivan Rusyn, Alexander Tropsha, Vinicius M. Alves
Publikováno v:
Alternatives to Laboratory Animals. 49:73-82
New Approach Methodologies (NAMs) that employ artificial intelligence (AI) for predicting adverse effects of chemicals have generated optimistic expectations as alternatives to animal testing. However, the major underappreciated challenge in developi
Autor:
Charles Schmitt, Vinicius M. Alves, Konstantin I. Popov, Alexander Tropsha, Cleber C. Melo-Filho, Daniel Korn, Nathaniel J. Moorman, Tesia Bobrowski, Scott S. Auerbach, Eugene N. Muratov
Publikováno v:
Drug Discovery Today
Graphical abstract
Highlights • COVID-19 has caused the most rapid research response to a pandemic in recent history. • After epidemics end, less research is performed on the causative agent. • Except for HIV/AIDS, responses to previous ep
Highlights • COVID-19 has caused the most rapid research response to a pandemic in recent history. • After epidemics end, less research is performed on the causative agent. • Except for HIV/AIDS, responses to previous ep
Autor:
Stephanie Holmgren, Shannon M. Bell, Jessica Wignall, Christopher G. Duncan, Richard K. Kwok, Ryan Cronk, Kimberly Osborn, Steven Black, Anne Thessen, Charles Schmitt
Publikováno v:
International Journal of Environmental Research and Public Health. 20:2317
Harmonized language is essential to finding, sharing, and reusing large-scale, complex data. Gaps and barriers prevent the adoption of harmonized language approaches in environmental health sciences (EHS). To address this, the National Institute of E