Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Charles S. Zuker"'
Autor:
Mengtong Li, Hwei-Ee Tan, Zhengyuan Lu, Katherine S. Tsang, Ashley J. Chung, Charles S. Zuker
Publikováno v:
Nature. 610:722-730
The perception of fat evokes strong appetitive and consummatory responses1. Here we show that fat stimuli can induce behavioural attraction even in the absence of a functional taste system2,3. We demonstrate that fat acts after ingestion via the gut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5046c010cdea8baea7fe58d8fd96d3e
https://doi.org/10.1038/s41586-022-05266-z
https://doi.org/10.1038/s41586-022-05266-z
Autor:
Alexander C. Sisti, Yossef Goffer, Miguel Villavicencio, Katherine Tsang, Charles S. Zuker, Hwei-Ee Tan, Martin Vignovich, Hao Jin
Publikováno v:
Yearbook of Paediatric Endocrinology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c01af582ddb32dd8eddc12b4df33fff
https://doi.org/10.1530/ey.18.15.6
https://doi.org/10.1530/ey.18.15.6
Autor:
Yueqing Peng, Xiaoke Chen, Charles S. Zuker, Sarah Gillis-Smith, Li Wang, Nicholas J. P. Ryba, C. Daniel Salzman, Juen Zhang
Publikováno v:
Nature
The ability of the taste system to identify a tastant (what it tastes like) enables animals to recognize and discriminate between the different basic taste qualities1,2. The valence of a tastant (whether it is appetitive or aversive) specifies its he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440cc2ce59dfd7c69cdbb6ebf14b1a2d
http://europepmc.org/articles/PMC6201270
http://europepmc.org/articles/PMC6201270
Publikováno v:
Nature. 548:330-333
In mammals, taste buds typically contain 50-100 tightly packed taste-receptor cells (TRCs), representing all five basic qualities: sweet, sour, bitter, salty and umami. Notably, mature taste cells have life spans of only 5-20 days and, consequently,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f1c403e3d47e9065c12fdc3305ee587
https://doi.org/10.1038/nature23299
https://doi.org/10.1038/nature23299
Autor:
Mark A. Hoon, David A. Yarmolinsky, Michael Rutlin, Yueqing Peng, Leah A. Pogorzala, Charles S. Zuker
Publikováno v:
Neuron. 92:1079-1092
Perception of the thermal environment begins with the activation of peripheral thermosensory neurons innervating the body surface. To understand how temperature is represented in vivo, we used genetically encoded calcium indicators to measure tempera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cfd0a695e12825a20733c0fdf7bd742
https://doi.org/10.1016/j.neuron.2016.10.021
https://doi.org/10.1016/j.neuron.2016.10.021
Autor:
Yossef Goffer, Miguel Villavicencio, Katherine Tsang, Charles S. Zuker, Hao Jin, Alexander C. Sisti, Hwei-Ee Tan, Martin Vignovich
Publikováno v:
Nature
The taste of sugar is one of the most basic sensory percepts for humans and other animals. Animals can develop a strong preference for sugar even if they lack sweet taste receptors, indicating a mechanism independent of taste1–3. Here we examined t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1124ec1bcc9e8824a482be67d98ee357
https://pubmed.ncbi.nlm.nih.gov/32350437
https://pubmed.ncbi.nlm.nih.gov/32350437
Publikováno v:
Cell. 184:257-271.e16
Hardwired circuits encoding innate responses have emerged as an essential feature of the mammalian brain. Sweet and bitter evoke opposing predetermined behaviors. Sweet drives appetitive responses and consumption of energy-rich food sources, whereas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3409de364b9882445a840d68e97ca975
https://doi.org/10.1016/j.cell.2020.12.014
https://doi.org/10.1016/j.cell.2020.12.014
Publikováno v:
Nature
Thirst is the basic instinct to drink water. Previously, it was shown that neurons in several circumventricular organs of the hypothalamus are activated by thirst-inducing conditions. Here we identify two distinct, genetically separable neural popula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cb39d90edc3e151559d833fd64208e
https://doi.org/10.1038/nature14108
https://doi.org/10.1038/nature14108
Autor:
David A. Yarmolinsky, Sarah Gillis-Smith, Mark J. Schnitzer, Charles S. Zuker, Nicholas J. P. Ryba, Jayaram Chandrashekar, Robert P. J. Barretto
Publikováno v:
Nature. 517:373-376
The mammalian taste system is responsible for sensing and responding to the five basic taste qualities: sweet, sour, bitter, salty and umami. Previously, we showed that each taste is detected by dedicated taste receptor cells (TRCs) on the tongue and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb049811bf5e5ca41e7f384c66b8be4
https://doi.org/10.1038/nature13873
https://doi.org/10.1038/nature13873
Publikováno v:
Cell. 179:392-402.e15
The ability to sense sour provides an important sensory signal to prevent the ingestion of unripe, spoiled, or fermented foods. Taste and somatosensory receptors in the oral cavity trigger aversive behaviors in response to acid stimuli. Here, we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0040564918dca1101b30f8b6743572fe
https://doi.org/10.1016/j.cell.2019.08.031
https://doi.org/10.1016/j.cell.2019.08.031