Zobrazeno 1 - 10
of 432
pro vyhledávání: '"Charles S Cox"'
Autor:
Henry W Caplan, Karthik S Prabhakara, Naama E Toledano Furman, Soheil Zorofchian, Cecilia Martin, Hasen Xue, Scott D Olson, Charles S Cox
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251601 (2021)
Traumatic brain injury (TBI) causes both physical disruption of the blood brain barrier (BBB) and altered immune responses that can lead to significant secondary brain injury and chronic inflammation within the central nervous system (CNS). Cell ther
Externí odkaz:
https://doaj.org/article/16a3ed46c4164efd89a59ec139a4fb13
Autor:
Katherine A Ruppert, Karthik S Prabhakara, Naama E Toledano-Furman, Sanjna Udtha, Austin Q Arceneaux, Hyeonggeun Park, An Dao, Charles S Cox, Scott D Olson
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233263 (2020)
In the U.S., approximately 1.7 million people suffer traumatic brain injury each year, with many enduring long-term consequences and significant medical and rehabilitation costs. The primary injury causes physical damage to neurons, glia, fiber tract
Externí odkaz:
https://doaj.org/article/eb0bfd7ea825487d97b1f735d695a7c3
Autor:
Shibani Pati, Michael H Gerber, Tyler D Menge, Kathryn A Wataha, Yuhai Zhao, John Adam Baumgartner, Jing Zhao, Phillip A Letourneau, Maria P Huby, Lisa A Baer, John R Salsbury, Rosemary A Kozar, Charles E Wade, Peter A Walker, Pramod K Dash, Charles S Cox, Marie-Francoise Doursout, John B Holcomb
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25171 (2011)
Hemorrhagic shock (HS) and trauma is currently the leading cause of death in young adults worldwide. Morbidity and mortality after HS and trauma is often the result of multi-organ failure such as acute lung injury (ALI) and acute respiratory distress
Externí odkaz:
https://doaj.org/article/f63b04b85a0f489097f95bfbf74c63cb
Autor:
Christopher T. Bolden, Max A. Skibber, Scott D. Olson, Miriam Zamorano Rojas, Samantha Milewicz, Brijesh S. Gill, Charles S. Cox
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract The Blood–Brain Barrier (BBB) is a highly-selective physiologic barrier responsible for maintaining cerebral homeostasis. Innovative in vitro models of the BBB are needed to provide useful insights into BBB function with CNS disorders like
Externí odkaz:
https://doaj.org/article/191ae9792cb245d0a86abb3a0373fb19
Autor:
Supinder S. Bedi, Michael C. Scott, Max A. Skibber, Akshita Kumar, Henry W. Caplan, Hasen Xue, David Sequeira, Alison L. Speer, Fanni Cardenas, Franciska Gudenkauf, Karen Uray, Amit K. Srivastava, Alan R. Prossin, Charles S. Cox
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Traumatic brain injury (TBI) results in activated microglia. Activated microglia can be measured in vivo by using positron emission topography (PET) ligand peripheral benzodiazepine receptor standardized uptake values (PBR28suv). Cell based
Externí odkaz:
https://doaj.org/article/3f8dcf5c326345358095521f0c347884
Autor:
Joseph D. Krocker, Madeline E. Cotton, Jacob B. Schriner, Baron K. Osborn, Michael M. Talanker, Yao-Wei W. Wang, Charles S. Cox, Charles E. Wade
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The TRPM4 gene codes for a membrane ion channel subunit related to inflammation in the central nervous system. Recent investigation has identified an association between TRPM4 single nucleotide polymorphisms (SNPs) rs8104571 and rs150391806
Externí odkaz:
https://doaj.org/article/d350293ca1d4451a890a0d90031f6b45
Autor:
Jacob B. Schriner, MD, J. Michael Van Gent, DO, M. Adam Meledeo, PhD, Scott D. Olson, PhD, Bryan A. Cotton, MD, Charles S. Cox, Jr, MD, Brijesh S. Gill, MD
Publikováno v:
Critical Care Explorations, Vol 5, Iss 6, p e0925 (2023)
OBJECTIVES:. This narrative review article seeks to highlight the effects of citrate on physiology during massive transfusion of the bleeding patient. DATA SOURCES:. A limited library of curated articles was created using search terms including “ci
Externí odkaz:
https://doaj.org/article/4c64afc797774a33815f693d2342280d
Akademický článek
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Autor:
Mitchell J. George, James Bynum, Prajeeda Nair, Andrew P. Cap, Charles E. Wade, Charles S. Cox, Brijesh S. Gill
Publikováno v:
Platelets, Vol 29, Iss 5, Pp 431-439 (2018)
The purpose of this review is to explore the relationship between platelet bioenergetics and biomechanics and how this relationship affects the clinical interpretation of platelet function devices. Recent experimental and technological advances highl
Externí odkaz:
https://doaj.org/article/ae4c39a1ff0a4153b64e4ed27687494f
Autor:
Sean I. Savitz, Charles S. Cox
Publikováno v:
Nature Reviews Neurology. 19:9-18