Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Charles S, Redwood"'
Autor:
Arash Yavari, Mohamed Bellahcene, Annalisa Bucchi, Syevda Sirenko, Katalin Pinter, Neil Herring, Julia J. Jung, Kirill V. Tarasov, Emily J. Sharpe, Markus Wolfien, Gabor Czibik, Violetta Steeples, Sahar Ghaffari, Chinh Nguyen, Alexander Stockenhuber, Joshua R. St. Clair, Christian Rimmbach, Yosuke Okamoto, Dongmei Yang, Mingyi Wang, Bruce D. Ziman, Jack M. Moen, Daniel R. Riordon, Christopher Ramirez, Manuel Paina, Joonho Lee, Jing Zhang, Ismayil Ahmet, Michael G. Matt, Yelena S. Tarasova, Dilair Baban, Natasha Sahgal, Helen Lockstone, Rathi Puliyadi, Joseph de Bono, Owen M. Siggs, John Gomes, Hannah Muskett, Mahon L. Maguire, Youlia Beglov, Matthew Kelly, Pedro P. N. dos Santos, Nicola J. Bright, Angela Woods, Katja Gehmlich, Henrik Isackson, Gillian Douglas, David J. P. Ferguson, Jürgen E. Schneider, Andrew Tinker, Olaf Wolkenhauer, Keith M. Channon, Richard J. Cornall, Eduardo B. Sternick, David J. Paterson, Charles S. Redwood, David Carling, Catherine Proenza, Robert David, Mirko Baruscotti, Dario DiFrancesco, Edward G. Lakatta, Hugh Watkins, Houman Ashrafian
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)
AMPK regulates cellular energy balance using its γ subunit as an energy sensor of cellular AMP and ADP to ATP ratios. Here, the authors show that γ2 AMPK activation lowers heart rate by reducing the activity of pacemaker cells, whereas loss of γ2
Externí odkaz:
https://doaj.org/article/93dc1bb6f94248b0bbd5f23512479816
Autor:
Olga E. Karpicheva, Stanislava V. Avrova, Andrey L. Bogdanov, Vladimir V. Sirenko, Charles S. Redwood, Yurii S. Borovikov
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5829
The substitution for Arg168His (R168H) in γ-tropomyosin (TPM3 gene, Tpm3.12 isoform) is associated with congenital muscle fiber type disproportion (CFTD) and muscle weakness. It is still unclear what molecular mechanisms underlie the muscle dysfunct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e602661343926ab19a3aee0c2710c4df
https://doi.org/10.3390/ijms24065829
https://doi.org/10.3390/ijms24065829
Autor:
Acga Cheng, Jennifer Ann Harikrishna, Charles S. Redwood, Lei Cheng Lit, Swapan K. Nath, Kek Heng Chua
Publikováno v:
International Journal of Molecular Sciences. 23:3976
The understanding of how genetic information may be inherited through generations was established by Gregor Mendel in the 1860s when he developed the fundamental principles of inheritance. The science of genetics, however, began to flourish only duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f84491d68b066f0ae7ffd37c2ee1ff4
https://doi.org/10.3390/ijms23073976
https://doi.org/10.3390/ijms23073976
Autor:
Olga E, Karpicheva, Armen O, Simonyan, Nikita A, Rysev, Charles S, Redwood, Yurii S, Borovikov
Publikováno v:
International Journal of Molecular Sciences
We have used the technique of polarized microfluorimetry to obtain new insight into the pathogenesis of skeletal muscle disease caused by the Gln147Pro substitution in β-tropomyosin (Tpm2.2). The spatial rearrangements of actin, myosin and tropomyos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0fe044e21d801edc7f9b6e716f83665
https://pubmed.ncbi.nlm.nih.gov/33066566
https://pubmed.ncbi.nlm.nih.gov/33066566
Autor:
Stanislava V, Avrova, Olga E, Karpicheva, Armen O, Simonyan, Vladimir V, Sirenko, Charles S, Redwood, Yurii S, Borovikov
Publikováno v:
Biochemical and biophysical research communications. 515(2)
Substitution of Ala for Thr residue in 155th position in γ-tropomyosin (Tpm3.12) is associated with muscle weakness. To understand the mechanisms of this defect, we studied the Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f19784ab95dd2ac1dfd47f81791acbd9
https://pubmed.ncbi.nlm.nih.gov/31155291
https://pubmed.ncbi.nlm.nih.gov/31155291
Autor:
Christopher N Toepfer, Hiroko Wakimoto, Amanda C Garfinkel, Barbara McDonough, Dan Liao, Jianming Jiang, Angela Tai, Josh Gorham, Ida G Lund, Mingyue Lun, Thomas L Lynch, Sakthivel Sadayappan, Charles S Redwood, Hugh Watkins, Jonathan Seidman, Christine Seidman
Publikováno v:
Circulation Research. 123
The mechanisms by which truncating mutations in MYBPC3 (encoding cardiac myosin binding protein-C; cMyBPC) or myosin missense mutations cause hyper-contractility and poor relaxation in hypertrophic cardiomyopathy (HCM) are incompletely understood. Us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cf320840e83064d69f587f822fdcdff
https://doi.org/10.1161/res.123.suppl_1.571
https://doi.org/10.1161/res.123.suppl_1.571
Autor:
Stanislava V, Avrova, Olga E, Karpicheva, Nikita A, Rysev, Armen O, Simonyan, Vladimir V, Sirenko, Charles S, Redwood, Yurii S, Borovikov
Publikováno v:
Biochemical and biophysical research communications. 502(2)
The E41K mutation in TPM2 gene encoding muscle regulatory protein beta-tropomyosin is associated with nemaline myopathy and cap disease. The mutation results in a reduced Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99467f8acf4d3e6f8fc969157522a7c0
https://pubmed.ncbi.nlm.nih.gov/29792862
https://pubmed.ncbi.nlm.nih.gov/29792862
Autor:
Christopher N, Toepfer, Hiroko, Wakimoto, Amanda C, Garfinkel, Barbara, McDonough, Dan, Liao, Jianming, Jiang, Angela C, Tai, Joshua M, Gorham, Ida G, Lunde, Mingyue, Lun, Thomas L, Lynch, James W, McNamara, Sakthivel, Sadayappan, Charles S, Redwood, Hugh C, Watkins, Jonathan G, Seidman, Christine E, Seidman
Publikováno v:
Science translational medicine. 11(476)
The mechanisms by which truncating mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::935151f207e3126a0829227d99d0f522
https://pubmed.ncbi.nlm.nih.gov/30755739
https://pubmed.ncbi.nlm.nih.gov/30755739
Publikováno v:
Nature Precedings
New data on the molecular mechanism of the regulation of ATPase cycle by troponin-tropomyosin system have been obtained in reconstructed muscle fibers by using the polarized fluorescence technique, which allowed us following the azimuthal movements o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______984::86bb382fcddf530f9599d3b952f1a2f9
http://hdl.handle.net/10101/npre.2007.1391.1
http://hdl.handle.net/10101/npre.2007.1391.1
