Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Charles Reichman"'
Autor:
Minh Tuyet Ma, Saiaditya Badeti, Chih-Hsiung Chen, James Kim, Alok Choudhary, Bill Honnen, Charles Reichman, David Calianese, Abraham Pinter, Qingkui Jiang, Lanbo Shi, Renping Zhou, Huanbin Xu, Qingsheng Li, William Gause, Dongfang Liu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is highly contagious and presents a significant public health issue. Current therapies used to treat coronavirus disease 2019 (COVID-19) include monoclonal antibody cocktail, convalescent p
Externí odkaz:
https://doaj.org/article/bed4d20d522a4d9d80692c410188687e
Autor:
Susan Zolla-Pazner, Allan deCamp, Peter B Gilbert, Constance Williams, Nicole L Yates, William T Williams, Robert Howington, Youyi Fong, Daryl E Morris, Kelly A Soderberg, Carmela Irene, Charles Reichman, Abraham Pinter, Robert Parks, Punnee Pitisuttithum, Jaranit Kaewkungwal, Supachai Rerks-Ngarm, Sorachai Nitayaphan, Charla Andrews, Robert J O'Connell, Zhi-yong Yang, Gary J Nabel, Jerome H Kim, Nelson L Michael, David C Montefiori, Hua-Xin Liao, Barton F Haynes, Georgia D Tomaras
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87572 (2014)
UnlabelledIn the RV144 HIV-1 vaccine efficacy trial, IgG antibody (Ab) binding levels to variable regions 1 and 2 (V1V2) of the HIV-1 envelope glycoprotein gp120 were an inverse correlate of risk of HIV-1 infection. To determine if V1V2-specific Abs
Externí odkaz:
https://doaj.org/article/908050f48a3743e69cae612588e66678
Autor:
Alfred Lardizabal, Pratik Datta, William J. Honnen, Leeba Lederer, Hannah K. Dewald, Henry F. Raymond, Jared Radbel, Rahul Ukey, Alberta Onyuka, Patricia Fitzgerald-Bocarsly, Heta Parmar, Valentina Guerrini, Tanaya Bhowmick, Jason Roy, Melissa Woortman, Emily S. Barrett, Charles Reichman, Aliza L. Leiser, Alok Choudhary, Steven K. Libutti, Martin J. Blaser, Mary O Caryannopoulos, Reynold A. Panettieri, Pankaj Mishra, Maria Laura Gennaro, Sabiha Hussain, Maria Gloria Dominguez-Bello, Jeffrey L. Carson, Yingda L. Xie, Natalie Bruiners, Stanley H. Weiss, Abraham Pinter, Deborah Handler, Daniel B. Horton, Sugeet Jagpal
Monitoring the burden and spread of infection with the new coronavirus SARS-CoV-2, whether within small communities or in large geographical settings, is of paramount importance for public health purposes. Serology, which detects the host antibody re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3a99f94a18c2701adcf0931d7a3d23f
https://doi.org/10.1101/2021.07.09.21260266
https://doi.org/10.1101/2021.07.09.21260266
Autor:
Rolf A. Brekken, Sukhwinder Singh, Abraham Pinter, William J. Honnen, Maria Laura Gennaro, Raymond B. Birge, Varsha Gadiyar, Tamara Kreiss, Sergei V. Kotenko, Kevin C. Lahey, Viralkumar Davra, David S. Ucker, Dabbu Kumar Jaijyan, Charles Reichman, John J. Siekierka, Canan Kasikara, Alok Choudhary, David Calianese, Ke Geng
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 207(2)
Phosphatidylserine (PS)-targeting monoclonal Abs (mAbs) that directly target PS and target PS via β2-gp1 (β2GP1) have been in preclinical and clinical development for over 10 y for the treatment of infectious diseases and cancer. Although the inten
Autor:
Leeba Lederer, Valentina Guerrini, Tanaya Bhowmick, William J. Honnen, Reynold A. Panettieri, Steven K. Libutti, Maria Gloria Dominguez-Bello, Jason Roy, Aliza L. Leiser, Maria Laura Gennaro, Alok Choudhary, Daniel B. Horton, Sugeet Jagpal, Pratik Datta, Mary Carayannopoulos, Stanley H. Weiss, Yingda L. Xie, Deborah Handler, Heta Parmar, Abraham Pinter, Jared Radbel, Alfred Lardizabal, Hannah K. Dewald, Natalie Bruiners, Melissa Woortman, Emily S. Barrett, Patricia Fitzgerald-Bocarsly, Rahul Ukey, Pankaj K. Mishra, Henry F. Raymond, Sabiha Hussain, Charles Reichman, Jeffrey L. Carson, Alberta Onyuka, Martin J. Blaser
Publikováno v:
Journal of Immunological Methods
medRxiv
article-version (status) pre
article-version (number) 1
medRxiv
article-version (status) pre
article-version (number) 1
Monitoring the burden and spread of infection with the new coronavirus SARS-CoV-2, whether within small communities or in large geographical settings, is of paramount importance for public health purposes. Serology, which detects the host antibody re
Autor:
Kazuya Machida, Wojciech Jankowski, Canan Kasikara, Tong Liu, Raymond B. Birge, Jing Li, Hong Li, Khanh-Quynh N. Nguyen, Charalampos G. Kalodimos, Charles Reichman, Peter Hornbeck, Ganapathy Sriram, Tamjeed Saleh
Publikováno v:
Oncogene
Crk, the prototypical member of a class of Src homology-2 (SH2) and Src homology-3 (SH3) domain containing proteins that controls the coordinated assembly of signaling complexes, is regulated by phosphorylation of Y221 in the linker region, which for
Autor:
Kazuya Machida, A. Tunceroglu, Ganapathy Sriram, Jun Li, Peter Hornbeck, Q. Ge, Charalampos G. Kalodimos, Raymond B. Birge, Charles Reichman, N. Kaushal, Bruce J. Mayer, Tamjeed Saleh
Publikováno v:
Oncogene. 30:4645-4655
Here, we report the identification and characterization of a novel tyrosine phosphorylation site in the carboxy-terminal Src Homology 3 (SH3) (SH3C) domain of the Crk adaptor protein. Y251 is located in the highly conserved RT loop structure of the S
Publikováno v:
Biochemistry. 46:10828-10840
Crk II and Crk L have both cytosolic and nuclear functions. While Crk L is a bona fide nuclear signaling protein because of its ability to bind tyrosine-phosphorylated STAT5 and act as a transcriptional coactivator, the function of nuclear Crk II is
Publikováno v:
Molecular Cell. 25(3):413-426
Autoinhibition is being widely used in nature to repress otherwise constitutive protein activities and is typically regulated by extrinsic factors. Here we show that autoinhibition can be controlled by an intrinsic intramolecular switch afforded by p
Autor:
Yan Liu, Andras Fiser, Charles Reichman, Sukhwinder Singh, Hong Li, Kamalendra Singh, Raymond B. Birge, J. Eduardo Fajardo
Publikováno v:
Oncogene. 24:8187-8199
To gain a better understanding of how Crk II regulates the function of the Abl tyrosine kinase, we explored the function of the C-terminal linker and SH3 domain, a region of Crk II that is still poorly understood. Molecular modeling, tryptophan fluor