Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Charles R. Midgett"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Enteric infections caused by the gram-negative bacteria enterotoxigenic Escherichia coli (ETEC), Vibrio cholerae, Shigella flexneri, and Salmonella enterica are among the most common and affect billions of people each year. These bacteria co
Externí odkaz:
https://doaj.org/article/534105fb0ec64ce69e4cffc37bd6633c
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 4 (2012)
Ligand-gated ion channels couple the free energy of agonist binding to the gating of selective transmembrane ion pores, permitting cells to regulate ion flux in response to external chemical stimuli. However, the stereochemical mechanisms responsible
Externí odkaz:
https://doaj.org/article/adb7b3511325494fa5812d31404c2a3f
Autor:
Charles R. Midgett, F. Jon Kull
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783031229961
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6379c12f39aa8efe7246225be8228a36
https://doi.org/10.1007/978-3-031-22997-8_14
https://doi.org/10.1007/978-3-031-22997-8_14
Publikováno v:
ACS Med Chem Lett
[Image: see text] The chiral conformation that palmitoleic acid takes when it is bound to ToxT, the master regulator of virulence genes in the bacterial pathogen Vibrio cholerae, was used as inspiration to design a novel class of fatty acid mimetics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36462b90fa306aa6ee13402b23cbcde
https://pubmed.ncbi.nlm.nih.gov/34531958
https://pubmed.ncbi.nlm.nih.gov/34531958
Enterotoxigenic Escherichia coli (ETEC) is a common cause of diarrheal disease worldwide and a frequent cause of travelers’ diarrhea. In addition to the production of enterotoxins, studies with human volunteers established ETEC virulence is depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae5137590f850d0bc0db72780b87c512
https://doi.org/10.1101/2020.10.05.326769
https://doi.org/10.1101/2020.10.05.326769
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1e23149540be0bf812e12f7f9db62c
https://doi.org/10.1038/s41598-020-69095-8
https://doi.org/10.1038/s41598-020-69095-8
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
ToxR is a transmembrane transcription factor that, together with its integral membrane periplasmic binding partner ToxS, is conserved across the Vibrio family. In some pathogenic Vibrios, including V. parahaemolyticus and V. cholerae, ToxR is require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4950186d3cd2dd133ae7311ffce5cc
Autor:
Salvador Almagro-Moreno, F. Jon Kull, Maria Pellegrini, Charles R. Midgett, Karen Skorupski, Ronald K. Taylor
Publikováno v:
Molecular Microbiology. 105:258-272
ToxR is a transmembrane transcription factor that is essential for virulence gene expression and human colonization by Vibrio cholerae. ToxR requires its operon partner ToxS, a periplasmic integral membrane protein, for full activity. These two prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d936a3edde9755704e338a6edbb8f348
https://doi.org/10.1111/mmi.13699
https://doi.org/10.1111/mmi.13699
Autor:
Keiichi Torimitsu, Jelena Baranovic, Charles R. Midgett, Chandra S. Ramanujan, Dean R. Madden, John F. Ryan, Nahoko Kasai
Publikováno v:
Journal of Biological Chemistry. 288:8647-8657
AMPA receptors (AMPARs) are glutamate-gated ion channels ubiquitous in the vertebrate central nervous system, where they mediate fast excitatory neurotransmission and act as molecular determinants of memory formation and learning. Together with detai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dea6393e7a5e5d88369667d00e927292
https://doi.org/10.1074/jbc.m112.422105
https://doi.org/10.1074/jbc.m112.422105
Publikováno v:
The International Journal of Robotics Research. 30:730-754
Single-particle electron microscopy is an experimental technique that is used to determine the three-dimensional (3D) structure of biological macromolecules and the complexes that they form. In general, image processing techniques and reconstruction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9500746bda6b060b8b1dcc68cd7a7590
https://doi.org/10.1177/0278364911400220
https://doi.org/10.1177/0278364911400220