Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Charles R. Handorf"'
Autor:
Lawrence M Pfeffer, Kui Li, Jaquelyn F Fleckenstein, Tony N Marion, Joel Diament, Chuan He Yang, Susan R Pfeffer, Meiyun Fan, Elizabeth Handorf, Charles R Handorf
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104202 (2014)
Infection with the hepatitis C virus (HCV) is a major cause of chronic liver diseases and hepatocellular carcinoma worldwide, and thus represents a significant public health problem. The type I interferon (IFN), IFNα, has been successful in treating
Externí odkaz:
https://doaj.org/article/863f31a63f774ff18820ba4b3641ffbd
Autor:
Weining Zhen, Leonard B. Saltz, Marvaretta Stevenson, G. Weldon Gilcrease, Mary Anne Bergman, Renato Lenzi, Asif Rashid, Charles R. Handorf, Gauri R. Varadhachary, Keith D. Eaton, Justin M M Cates, Richard Schwab, Lawrence N. Shulman, John E. Phay, Mihaela C. Cristea, Daniel W. Bowles, Efrat Dotan, David S. Ettinger, David S. Gierada, Panagiotis Fidias, Renuka Iyer, Deborah A. Freedman-Cass, Jonathan S. Zager, Mark Agulnik, Kelly N. Godby, Jeffrey B. Smerage
Publikováno v:
Journal of the National Comprehensive Cancer Network. 12:969-974
The NCCN Guidelines for Occult Primary tumors provide recommendations for the evaluation, workup, management, and follow-up of patients with occult primary tumors (cancers of unknown primary). These NCCN Guidelines Insights summarize major discussion
Autor:
Charles R. Handorf
Publikováno v:
Journal of the National Comprehensive Cancer Network. 9:1415-1420
Molecular medicine is rapidly changing the diagnosis and management of cancer of unknown primary. The science, business, and economics of the genomic revolution have moved at such a pace that coordinating practical application of all available tools,
Publikováno v:
Journal of Biological Chemistry. 286:39172-39178
MicroRNA-21 (miR-21) is overexpressed in many human tumors and has been linked to various cellular processes altered in cancer. miR-21 is also up-regulated by a number of inflammatory agents, including IFN, which is of particular interest considering
Autor:
Martin A. Croce, Timothy C. Fabian, Dan H. Shell, Charles R. Handorf, Norma M. Edwards, Jeffrey A. Claridge
Publikováno v:
The American Surgeon. 72:1168-1175
Neointimal hyperplasia (NH) is the most significant contributing factor to long-term vascular graft failure. Inflammation is known to be important in its development; however, the role of bacterial infection is unclear. We examined the effect of cont
Autor:
Omran R. Abul-Khoudoud, Daniel H. Shell, Timothy C. Fabian, Lisa K. Jennings, Catherine Cagiannos, Waldemar G. DeRijk, Elizabeth A. Tolley, Charles R. Handorf
Publikováno v:
Journal of Vascular Surgery. 42:980-988
ObjectiveWe tested the hypothesis that rapamycin coated onto, and eluted from, expanded polytetrafluoroethylene (ePTFE) grafts would diminish neointimal hyperplasia in a porcine model.MethodsRapamycin (also called sirolimus) was coated onto the lumin
Autor:
Charles R. Handorf, Daniel H. Shell, Catherine Cagiannos, T Wright Jernigan, Martin A. Croce, Timothy C. Fabian
Publikováno v:
Annals of Surgery. 239:733-740
Surgical options for vascular reconstruction in a contaminated field are limited and include prosthetic reconstruction or ligation with extra-anatomic bypass. With prosthetic insertion, rates of graft infection and failures (pseudoaneurysms and throm
Autor:
Meiyun Fan, Lawrence M. Pfeffer, Charles R. Handorf, Kui Li, Elizabeth Handorf, Joel Diament, Tony N. Marion, Jaquelyn Fleckenstein, Chuan He Yang, Susan R. Pfeffer
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 8, p e104202 (2014)
PLoS ONE, Vol 9, Iss 8, p e104202 (2014)
Infection with the hepatitis C virus (HCV) is a major cause of chronic liver diseases and hepatocellular carcinoma worldwide, and thus represents a significant public health problem. The type I interferon (IFN), IFNα, has been successful in treating
Autor:
Andrew M. Davidoff, Elena M. Paulus, Junming Yue, Charles R. Handorf, Chuan He Yang, Amira Hosni-Ahmed, Sohail Qayyum, Michelle Sims, Susan R. Pfeffer, Lawrence M. Pfeffer, Meiyun Fan
Publikováno v:
The Journal of biological chemistry. 289(36)
Despite advances in surgery, imaging, chemotherapy, and radiation, patients with glioblastoma multiforme (GBM), the most common histological subtype of glioma, have an especially dismal prognosis; >70% of GBM patients die within 2 years of diagnosis.
Autor:
Charles R. Handorf, F. Curtis Dohan, J. Edward Bass, Tulio E. Bertorini, Klaus E. Mönkemüller, J. Howard Jaster, Barry E. Gerald
Publikováno v:
Clinical Imaging. 21:17-22
We report a biopsy-proven case of sarcoidosis limited to the spinal cord and responsive to treatment with oral corticosteroids. Involvement of the spinal cord by systemic sarcoidosis is uncommon and is associated with several unusual pathological and