Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Charles R. Ellefson"'
Autor:
Charles R. Ellefson, John W Cusic
Publikováno v:
Journal of Medicinal Chemistry. 19:1161-1164
Publikováno v:
Journal of Medicinal Chemistry. 21:340-343
Some dihydro- and hexahydro-2-dialkylaminoalkyl-9-phenyl-1H-indeno[2,1-c]pyridines were prepared and found to possess significant antiarrhythmic activity. Hydrogenation of the dihydro compounds 4 produced the allcis-hexahydro isomers 5 which were con
Publikováno v:
Journal of Medicinal Chemistry. 23:977-980
The synthesis of 8-(methoxyphenyl)-1,2,3,4-tetrahydroisoquinolines using aryloxazolines as key intermediates is described. Nucleophilic displacement on an o-methoxyphenyloxazoline by an aryl Grignard reagent, followed by electrophilic substitution at
Autor:
Charles R. Ellefson
Publikováno v:
The Journal of Organic Chemistry. 44:1533-1536
Publikováno v:
Journal of Medicinal Chemistry. 21:952-957
2-Amino-4-aryl-3H-1,5-benzodiazepines were prepared and evaluated for potential neuroleptic activity. Compound 60 showed some activity in the four assays; however, the activity was not consistently observed among other members of the series. The data
Publikováno v:
The Journal of Organic Chemistry. 35:802-805
Publikováno v:
Chemischer Informationsdienst. 12
The synthesis of 8-(methoxyphenyl)-1,2,3,4-tetrahydroisoquinolines using aryloxazolines as key intermediates is described. Nucleophilic displacement on an o-methoxyphenyloxazoline by an aryl Grignard reagent, followed by electrophilic substitution at
Autor:
John W Cusic, Charles R. Ellefson
Publikováno v:
Chemischer Informationsdienst. 8
Publikováno v:
Chemischer Informationsdienst. 10
2-Amino-4-aryl-3H-1,5-benzodiazepines were prepared and evaluated for potential neuroleptic activity. Compound 60 showed some activity in the four assays; however, the activity was not consistently observed among other members of the series. The data
Publikováno v:
Chemischer Informationsdienst. 9
Some dihydro- and hexahydro-2-dialkylaminoalkyl-9-phenyl-1H-indeno[2,1-c]pyridines were prepared and found to possess significant antiarrhythmic activity. Hydrogenation of the dihydro compounds 4 produced the allcis-hexahydro isomers 5 which were con