Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Charles R. Connell"'
Autor:
Leroy Hood, Steven M. Menchen, Jane Z. Sanders, Peter J. Hughes, Charles R. Connell, A. Albert Petterson, Malcolm Raff, David B. Teplow
Publikováno v:
Electrophoresis. 12:3-11
A new method of signal analysis for automated fluorescence-based DNA sequencing is presented. Signal resolution is a limiting factor in obtaining accurate sequence information beyond 400-450 nucleotides per gel lane. We have developed a computer prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4caeb1d02d9da81b8f6b6341c979fa5e
https://doi.org/10.1002/elps.1150120103
https://doi.org/10.1002/elps.1150120103
Autor:
Joshua I. Molho, Thomas W. Kenny, Pamela M. St. John, Chahid Kamel Ghaddar, Timothy M. Woudenberg, Manish Deshpande, Godfrey Mungal, John R. Gilbert, Amy E. Herr, Charles R. Connell
Publikováno v:
SPIE Proceedings.
This paper presents a numerical framework for design-based analyses of electrokinetic flow in interconnects. Electrokinetic effects, which can be broadly divided into electrophoresis and electroosmosis, are of importance in providing a transport mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aac20f81ea98b73dddbb37ee6c6859dc
https://doi.org/10.1117/12.322088
https://doi.org/10.1117/12.322088
Autor:
Manish Deshpande, Timothy M. Woudenberg, P. Paul, Thomas W. Kenny, Charles R. Connell, Joshua I. Molho, P.M. St John, M. Garguillo, Jill Gilbert, Amy E. Herr, M. G. Mungal
Publikováno v:
1998 Solid-State, Actuators, and Microsystems Workshop Technical Digest.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::965e5d2faa4b47dc2afb94b172afa878
https://doi.org/10.31438/trf.hh1998.24
https://doi.org/10.31438/trf.hh1998.24
Autor:
Eric S. Nordman, Charles R. Connell
Publikováno v:
SPIE Proceedings.
A second generation optical design for the ABI PRISMTM 377 DNA sequencer enhances sensitivity and increases sequencing throughput by taking advantage of simultaneous four color detection using a spectrograph and CCD array. On-axis laser illumination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::341356a0550eb081ff88e7b14142815b
https://doi.org/10.1117/12.237617
https://doi.org/10.1117/12.237617
Publikováno v:
Nucleic acids research. 21(16)
Nick-translation PCR was performed with fluorogenic probes. Two probes were used: one complementary to a sequence containing the F508 codon of the normal human cystic fibrosis (CF) gene (wt DNA) and one complementary to a sequence containing the delt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184ba42bb9ed60a754217a6aae9596bd
https://pubmed.ncbi.nlm.nih.gov/8367293
https://pubmed.ncbi.nlm.nih.gov/8367293
Autor:
Charles R. Connell, Nicolette D. Halloran, Richard D. Cheng, Linda G. Lee, Carl W. Fuller, Rick K. Wilson, Sam Lee Woo, Bernard F. McArdle
Publikováno v:
Nucleic acids research. 20(10)
The incorporation of fluorescently labeled dideoxynucleotides by T7 DNA polymerase is optimized by the use of Mn2+, fluorescein analogs and four 2'-deoxyribonucleoside 5'-O-(1-thiotriphosphates) (dNTP alpha S's). The one-tube extension protocol was t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f12e20e63358d39b38938e637ac04127
https://pubmed.ncbi.nlm.nih.gov/1598205
https://pubmed.ncbi.nlm.nih.gov/1598205
Publikováno v:
Accounts of Chemical Research. 15:73-79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba308048e7567b8c02e0e12c7a4445c3
https://doi.org/10.1021/ar00075a002
https://doi.org/10.1021/ar00075a002
Publikováno v:
Journal of the American Chemical Society. 99:1082-1087
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02bf239233306a199e478a2a033f3580
https://doi.org/10.1021/ja00446a018
https://doi.org/10.1021/ja00446a018
Autor:
Martin Gouterman, Charles R. Connell, Irwin C. Gunsalus, Stephen G. Sligar, Louise Karle Hanson, William A. Eaton
Publikováno v:
Journal of the American Chemical Society. 98:2672-2674
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e619c30d8c8212e4d7a42c08a2e23df8
https://doi.org/10.1021/ja00425a050
https://doi.org/10.1021/ja00425a050
Autor:
Stephen B. H. Kent, Robert J. Kaiser, Leroy Hood, Charles R. Connell, Lloyd M. Smith, Cheryl Heiner, Chris Dodd, Peter Hughes, Jane Z. Sanders
Publikováno v:
Nature. 321(6071)
We have developed a method for the partial automation of DNA sequence analysis. Fluorescence detection of the DNA fragments is accomplished by means of a fluorophore covalently attached to the oligonucleotide primer used in enzymatic DNA sequence ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb26d9260da0f2220f0ddd34d65ada10
https://pubmed.ncbi.nlm.nih.gov/3713851
https://pubmed.ncbi.nlm.nih.gov/3713851