Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Charles R. Ashby, Jr"'
Autor:
Yawen Dong, Tingting Ma, Ting Xu, Zhangyan Feng, Yonggui Li, Lingling Song, Xiaojun Yao, Charles R. Ashby, Jr, Ge-Fei Hao
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 10, Pp 4266-4295 (2024)
Proteolysis targeting chimera (PROTAC) technology represents a groundbreaking development in drug discovery, leveraging the ubiquitin‒proteasome system to specifically degrade proteins responsible for the disease. PROTAC is characterized by its uni
Externí odkaz:
https://doaj.org/article/8aa4210351db425b9ddf81c7e5082d5f
Autor:
Chandrabose Karthikeyan, Haneen Amawi, Charles R. Ashby, Jr., Vishwa M. Khare, Veronica Jones, N.S. Hari Narayana Moorthy, Piyush Trivedi, Amit K. Tiwari
Publikováno v:
Heliyon, Vol 5, Iss 5, Pp e01603- (2019)
A novel series of 3-((2-chloroquinolin-3-yl)methylene)indolin-2-ones were synthesized, using the ‘molecular hybridization approach’ and evaluated for anticancer efficacy. Eleven 3-((2-chloroquinolin-3-yl)methylene)indolin-2-ones (LM01 to LM11) we
Externí odkaz:
https://doaj.org/article/5c8f6396126143f1a5e510829e2594aa
Publikováno v:
International Journal of Infectious Diseases, Vol 55, Iss C, Pp 29-30 (2017)
Externí odkaz:
https://doaj.org/article/3e55382f10734bc083499b1db30798a4
Autor:
Kyle McIntosh, Jeffrey Sarver, Kristopher Mell, David J. Terrero, Charles R. Ashby Jr., Chris Reddy, Gregory O’ Neil, Jayachandra Babu Ramapuram, Amit K. Tiwari
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 25, Iss 5, Pp 817-837 (2020)
Isochrysis is commercially available marine algae used for animal feed, human nutrient supplements, and biodiesel. The Isochrysis species is one of five genera of haptophytes that produces unique, long-chain lipids known as alkenones that are promisi
Externí odkaz:
https://doaj.org/article/45055174d74947c0acbf60e1a431ead3
Autor:
Jagadish B Koya, Tong Shen, Geming Lu, Alex Gauthier, Lin Mantell, Charles R Ashby Jr, Sandra E. Reznik
Publikováno v:
Fortune Journal of Health Sciences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3033805a77cf3f230cbe88d50e45e0e3
https://doi.org/10.26502/fjhs.076
https://doi.org/10.26502/fjhs.076
Autor:
null Saurabh G. Vispute, null Jun-Jiang Chen, null Yue-Li Sun, null Kamlesh S. Sodani, null Satyakam Singh, null Yihang Pan, null Tanaji Talele, null Charles R. Ashby Jr, null Zhe-Sheng Chen
Publikováno v:
Journal of Cancer Research Updates. 2
In this study, we examined the in vitro effects of vemurafenib, a specific inhibitor of V600E mutated BRAFenzyme, on the response of cells overexpressing the ATP binding cassette (ABC) efflux transporters ABCG2, ABCB1, ABCC1 and ABCC10. Vemurafenib,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01169322445f84fc74cbd484bdaadbb8
https://doi.org/10.6000/1929-2279.2013.02.04.9
https://doi.org/10.6000/1929-2279.2013.02.04.9
Publikováno v:
Acta Materia Medica, Vol 2, Iss 2, Pp 255-259 (2023)
A significant proportion of patients who survive coronavirus disease of 2019 (COVID-19) develop a constellation of life-altering symptoms that persist long after the initial infection has resolved. This post-COVID-19 syndrome may result from the deve
Externí odkaz:
https://doaj.org/article/a0fa7943781c4e3d8f972ceebc51380e
Autor:
Vivek Chavda, Kelsee K. Zajac, Jenna Lynn Gunn, Pankti Balar, Avinash Khadela, Dixa Vaghela, Shruti Soni, Charles R. Ashby Jr., Amit K. Tiwari
Publikováno v:
Cancer Reports, Vol 6, Iss S1, Pp n/a-n/a (2023)
Abstract Background Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death worldwide. The incidence of HCC is affected by genetic and non‐genetic factors. Genetically, mutations in the genes, tumor protein P53 (TP53), catenin b
Externí odkaz:
https://doaj.org/article/4424294178794a84942280b3f312f2b2