Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Charles R Langelier"'
Autor:
Alexandra Tsitsiklis, PhD, Christina M Osborne, MD, Jack Kamm, PhD, Kayla Williamson, MS, Katrina Kalantar, PhD, Gytis Dudas, PhD, Saharai Caldera, BA, Amy Lyden, BA, Michelle Tan, BS, Norma Neff, PhD, Victoria Soesanto, BS, J Kirk Harris, PhD, Lilliam Ambroggio, PhD, Aline B Maddux, MD, Todd C Carpenter, MD, Ron W Reeder, PhD, Chris Locandro, MS, Eric A F Simões, ProfMD, Matthew K Leroue, MD, Mark W Hall, ProfMD, Athena F Zuppa, ProfMD, Joseph Carcillo, ProfMD, Kathleen L Meert, ProfMD, Anil Sapru, ProfMD, Murray M Pollack, ProfMD, Patrick S McQuillen, ProfMD, Daniel A Notterman, ProfMD, J Michael Dean, ProfMD, Matt S Zinter, MD, Brandie D Wagner, PhD, Joseph L DeRisi, ProfPhD, Peter M Mourani, ProfMD, Charles R Langelier, MDPhD
Publikováno v:
The Lancet Microbe, Vol 3, Iss 4, Pp e284-e293 (2022)
Summary: Background: Lower respiratory tract infections (LRTI) are a leading cause of critical illness and mortality in mechanically ventilated children; however, the pathogenic microbes frequently remain unknown. We combined traditional diagnostics
Externí odkaz:
https://doaj.org/article/bf9afb105f554ba7841ff015408ec805
Autor:
Natasha Spottiswoode, Alexandra Tsitsiklis, Victoria T. Chu, Hoang Van Phan, Catherine DeVoe, Christina Love, Rajani Ghale, Joshua Bloomstein, Beth Shoshana Zha, Cole P. Maguire, Abigail Glascock, Aartik Sarma, Peter M. Mourani, Katrina L. Kalantar, Angela Detweiler, Norma Neff, Sidney C. Haller, COMET Consortium, Joseph L. DeRisi, David J. Erle, Carolyn M. Hendrickson, Kirsten N. Kangelaris, Matthew F. Krummel, Michael A. Matthay, Prescott G. Woodruff, Carolyn S. Calfee, Charles R. Langelier
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Secondary bacterial pneumonia (2°BP) is associated with significant morbidity following respiratory viral infection, yet remains incompletely understood. In a prospective cohort of 112 critically ill adults intubated for COVID-19, we compar
Externí odkaz:
https://doaj.org/article/c54e44e92cce4848a4f22b7f58a64b95
Autor:
Lucile P. A. Neyton, Ravi K. Patel, Aartik Sarma, UCSF COMET Consortium, Andrew Willmore, Sidney C. Haller, Kirsten N. Kangelaris, Walter L. Eckalbar, David J. Erle, Matthew F. Krummel, Carolyn M. Hendrickson, Prescott G. Woodruff, Charles R. Langelier, Carolyn S. Calfee, Gabriela K. Fragiadakis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Dexamethasone is the standard of care for critically ill patients with COVID-19, but the mechanisms by which it decreases mortality and its immunological effects in this setting are not understood. Here we perform bulk and single-cell RNA se
Externí odkaz:
https://doaj.org/article/a07e6d9546564fe3af6acbe7a47ce91d
Autor:
Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E. Milliren, Jingjing Qi, Linda N. Geng, Grace A. McComsey, Charles B. Cairns, Lindsey R. Baden, Joanna Schaenman, Albert C. Shaw, Hady Samaha, Vicki Seyfert-Margolis, Florian Krammer, Lindsey B. Rosen, Hanno Steen, Caitlin Syphurs, Ravi Dandekar, Casey P. Shannon, Rafick P. Sekaly, Lauren I. R. Ehrlich, David B. Corry, Farrah Kheradmand, Mark A. Atkinson, Scott C. Brakenridge, Nelson I. Agudelo Higuita, Jordan P. Metcalf, Catherine L. Hough, William B. Messer, Bali Pulendran, Kari C. Nadeau, Mark M. Davis, Ana Fernandez Sesma, Viviana Simon, Harm van Bakel, Seunghee Kim-Schulze, David A. Hafler, Ofer Levy, Monica Kraft, Chris Bime, Elias K. Haddad, Carolyn S. Calfee, David J. Erle, Charles R. Langelier, Walter Eckalbar, Steven E. Bosinger, IMPACC Network, Bjoern Peters, Steven H. Kleinstein, Elaine F. Reed, Alison D. Augustine, Joann Diray-Arce, Holden T. Maecker, Matthew C. Altman, Ruth R. Montgomery, Patrice M. Becker, Nadine Rouphael
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Post-acute sequelae of SARS-CoV-2 (PASC) is a significant public health concern. We describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed from hospital admission for COVID-19 through one year after discharge. M
Externí odkaz:
https://doaj.org/article/ec0ddc29cd90460ca1ec27bea2b831b8
Autor:
Victoria T. Chu, Alexandra Tsitsiklis, Eran Mick, Lilliam Ambroggio, Katrina L. Kalantar, Abigail Glascock, Christina M. Osborne, Brandie D. Wagner, Michael A. Matthay, Joseph L. DeRisi, Carolyn S. Calfee, Peter M. Mourani, Charles R. Langelier
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Antimicrobial resistant lower respiratory tract infections are an increasing public health threat and an important cause of global mortality. The lung microbiome can influence susceptibility of respiratory tract infections and represents an
Externí odkaz:
https://doaj.org/article/a6e6c725bdd94596848389ca69371515
Autor:
Ian Kracalik, Alyssa G. Kent, Carlos H. Villa, Paige Gable, Pallavi Annambhotla, Gillian McAllister, Deborah Yokoe, Charles R. Langelier, Kelly Oakeson, Judith Noble-Wang, Orieji Illoh, Alison Laufer Halpin, Anne F. Eder, Sridhar V. Basavaraju
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 10, Pp 1979-1989 (2023)
During May 2018‒December 2022, we reviewed transfusion-transmitted sepsis cases in the United States attributable to polymicrobial contaminated apheresis platelet components, including Acinetobacter calcoaceticus‒baumannii complex or Staphylococc
Externí odkaz:
https://doaj.org/article/22513e47652c4f89aae3a2be2cbd34be
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-7 (2023)
Abstract This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2023. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2023 . Further information
Externí odkaz:
https://doaj.org/article/3a2a59f71fac413b97dd48fe97c0da3b
Prevalence of type-1 interferon autoantibodies in adults with non-COVID-19 acute respiratory failure
Autor:
Rajani Ghale, Natasha Spottiswoode, Mark S. Anderson, Anthea Mitchell, Grace Wang, Carolyn S. Calfee, Joseph L. DeRisi, Charles R. Langelier
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-4 (2022)
Abstract Auto-antibodies (Abs) to type I interferons (IFNs) are found in up to 25% of patients with severe COVID-19, and are implicated in disease pathogenesis. It has remained unknown, however, whether type I IFN auto-Abs are unique to COVID-19, or
Externí odkaz:
https://doaj.org/article/9d29d6413f03472e84cfd897a7ffe3f2
Autor:
Katherine D. Wick, Aleksandra Leligdowicz, Andrew Willmore, Sidney A. Carrillo, Rajani Ghale, Alejandra Jauregui, Suzanna S. Chak, Viet Nguyen, Deanna Lee, Chayse Jones, Robin Dewar, H. Clifford Lane, Kirsten N. Kangelaris, Carolyn M. Hendrickson, Kathleen D. Liu, Pratik Sinha, David J. Erle, Charles R. Langelier, Matthew F. Krummell, Prescott G. Woodruff, Carolyn S. Calfee, Michael A. Matthay, the COMET Consortium
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-11 (2022)
Abstract Background Studies quantifying SARS-CoV-2 have focused on upper respiratory tract or plasma viral RNA with inconsistent association with clinical outcomes. The association between plasma viral antigen levels and clinical outcomes has not bee
Externí odkaz:
https://doaj.org/article/e599ea26c99e4e01a0e78f4b33fff553
Autor:
Natasha Spottiswoode, Samantha Hao, Estella Sanchez-Guerrero, Angela M. Detweiler, Honey Mekonen, Norma Neff, Henriette Macmillan, Brian S. Schwartz, Joanne Engel, Joseph L. DeRisi, Steven A. Miller, Charles R. Langelier
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Multidrug-resistant (MDR) Pseudomonas aeruginosa has been declared a serious threat by the United States Centers for Disease Control and Prevention. Here, we used whole genome sequencing (WGS) to investigate recurrent P. aeruginosa bloodstream infect
Externí odkaz:
https://doaj.org/article/2828eeef9fac42af85ebf115d386a7b2