Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Charles R Gerfen"'
Autor:
Limei Zhang, Vito S Hernandez, Charles R Gerfen, Sunny Z Jiang, Lilian Zavala, Rafael A Barrio, Lee E Eiden
Publikováno v:
eLife, Vol 10 (2021)
The neuropeptide PACAP, acting as a co-transmitter, increases neuronal excitability, which may enhance anxiety and arousal associated with threat conveyed by multiple sensory modalities. The distribution of neurons expressing PACAP and its receptor,
Externí odkaz:
https://doaj.org/article/008cecb0de80419bb6fac61749b47659
Autor:
Michael N Economo, Nathan G Clack, Luke D Lavis, Charles R Gerfen, Karel Svoboda, Eugene W Myers, Jayaram Chandrashekar
Publikováno v:
eLife, Vol 5 (2016)
The structure of axonal arbors controls how signals from individual neurons are routed within the mammalian brain. However, the arbors of very few long-range projection neurons have been reconstructed in their entirety, as axons with diameters as sma
Externí odkaz:
https://doaj.org/article/9de8863688c64e2da58eaaea9e2e5b7f
Autor:
Michael B. Ryan, Allison E. Girasole, Andrew J. Flores, Emily L. Twedell, Matthew M. McGregor, Rea Brakaj, Ronald F. Paletzki, Thomas S. Hnasko, Charles R. Gerfen, Alexandra B. Nelson
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114483- (2024)
Summary: The striatum integrates dopaminergic and glutamatergic inputs to select preferred versus alternative actions. However, the precise mechanisms underlying this process remain unclear. One way to study action selection is to understand how it b
Externí odkaz:
https://doaj.org/article/825603252a4c4ae58da19f1e6899922c
Autor:
Kyuhyun Choi, Eugenio Piasini, Edgar Díaz-Hernández, Luigim Vargas Cifuentes, Nathan T. Henderson, Elizabeth N. Holly, Manivannan Subramaniyan, Charles R. Gerfen, Marc V. Fuccillo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
The prelimbic region of the prefrontal cortex is involved in goal-directed action. Here the authors investigate the function of the prelimbic pathways projecting along the anterior posterior striatal axis in value based decision making in male mice.
Externí odkaz:
https://doaj.org/article/e5b6bbe1ca9a40469d4e131d7e6ad87c
Autor:
Charles R. Gerfen
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2023)
The direct and indirect striatal pathways form a cornerstone of the circuits of the basal ganglia. Dopamine has opponent affects on the function of these pathways due to the segregation of the D1- and D2-dopamine receptors in the spiny projection neu
Externí odkaz:
https://doaj.org/article/f237a61914cc4e05b113c386769730c2
Publikováno v:
Cell Reports, Vol 34, Iss 8, Pp 108774- (2021)
Summary: Extensive hierarchical yet highly reciprocal interactions among cortical areas are fundamental for information processing. However, connectivity rules governing the specificity of such corticocortical connections, and top-down feedback proje
Externí odkaz:
https://doaj.org/article/155c18c5aaf941b0a3983b2c4afafabb
Autor:
Bryan M. Hooks, Andrew E. Papale, Ronald F. Paletzki, Muhammad W. Feroze, Brian S. Eastwood, Jonathan J. Couey, Johan Winnubst, Jayaram Chandrashekar, Charles R. Gerfen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
How corticostriatal connections of different pyramidal cell types are organized, particularly in convergent circuits, has not been evaluated in detail. Here, cell type-specific Cre-driver mice reveal that pyramidal tract-type corticostriatal projecti
Externí odkaz:
https://doaj.org/article/84c613a3ab84486487983e800ed1d0b3
Neuronal connections provide the scaffolding for neuronal function. Revealing the connectivity of functionally identified individual neurons is necessary to understand how activity patterns emerge and support behavior. Yet, the brain-wide presynaptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77a8ba8fc95ee2de869032b0abe85ea9
https://doi.org/10.1101/2023.05.25.542329
https://doi.org/10.1101/2023.05.25.542329
Publikováno v:
Neuron.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a74158ea3485ceb590fd157a61c97d80
https://doi.org/10.1016/j.neuron.2023.04.022
https://doi.org/10.1016/j.neuron.2023.04.022
Autor:
Hidehiko K. Inagaki, Susu Chen, Margreet C. Ridder, Pankaj Sah, Nuo Li, Zidan Yang, Hana Hasanbegovic, Zhenyu Gao, Charles R. Gerfen, Karel Svoboda
Publikováno v:
Cell, 185(6), 1065-1081.e23. Cell Press
Cell
Cell
Motor behaviors are often planned long before execution but only released after specific sensory events. Planning and execution are each associated with distinct patterns of motor cortex activity. Key questions are how these dynamic activity patterns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5edcb149b47e4066955718b0e4486db
https://doi.org/10.1016/j.cell.2022.02.006
https://doi.org/10.1016/j.cell.2022.02.006