Výsledky vyhledávání - "Charles R, Bridges"

Akademický článek

Clinical Validation of a Machine-Learned, Point-of-Care System to IDENTIFY Functionally Significant Coronary Artery Disease

Autor: Thomas D. Stuckey, Frederick J. Meine, Thomas R. McMinn, Jeremiah P. Depta, Brett A. Bennett, Thomas F. McGarry, William S. Carroll, David D. Suh, John A. Steuter, Michael C. Roberts, Horace R. Gillins, Farhad Fathieh, Timothy Burton, Navid Nemati, Ian P. Shadforth, Shyam Ramchandani, Charles R. Bridges, Mark G. Rabbat

Publikováno v: Diagnostics, Vol 14, Iss 10, p 987 (2024)

Many clinical studies have shown wide performance variation in tests to identify coronary artery disease (CAD). Coronary computed tomography angiography (CCTA) has been identified as an effective rule-out test but is not widely available in the USA,

Externí odkaz: https://doaj.org/article/1ace3123fc004960b45d1800947607d9

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Akademický článek

Pulmonary Hypertension Detection Non-Invasively at Point-of-Care Using a Machine-Learned Algorithm

Autor: Navid Nemati, Timothy Burton, Farhad Fathieh, Horace R. Gillins, Ian Shadforth, Shyam Ramchandani, Charles R. Bridges

Publikováno v: Diagnostics, Vol 14, Iss 9, p 897 (2024)

Artificial intelligence, particularly machine learning, has gained prominence in medical research due to its potential to develop non-invasive diagnostics. Pulmonary hypertension presents a diagnostic challenge due to its heterogeneous nature and sim

Externí odkaz: https://doaj.org/article/3019132082cd4b02b39fe0a8c2b63d95

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Akademický článek

Development of a Non-Invasive Machine-Learned Point-of-Care Rule-Out Test for Coronary Artery Disease

Autor: Timothy Burton, Farhad Fathieh, Navid Nemati, Horace R. Gillins, Ian P. Shadforth, Shyam Ramchandani, Charles R. Bridges

Publikováno v: Diagnostics, Vol 14, Iss 7, p 719 (2024)

The current standard of care for coronary artery disease (CAD) requires an intake of radioactive or contrast enhancement dyes, radiation exposure, and stress and may take days to weeks for referral to gold-standard cardiac catheterization. The CAD di

Externí odkaz: https://doaj.org/article/2a9a49e3c7ac4d80b1dc884650dea12f

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Akademický článek

Targeted Gene Delivery through the Respiratory System: Rationale for Intratracheal Gene Transfer

Autor: Michael G. Katz, Anthony S. Fargnoli, Sarah M. Gubara, Kenneth Fish, Thomas Weber, Charles R. Bridges, Roger J. Hajjar, Kiyotake Ishikawa

Publikováno v: Journal of Cardiovascular Development and Disease, Vol 6, Iss 1, p 8 (2019)

Advances in DNA- and RNA-based technologies have made gene therapy suitable for many lung diseases, especially those that are hereditary. The main objective of gene therapy is to deliver an adequate amount of gene construct to the intended target cel

Externí odkaz: https://doaj.org/article/eba4073123d04bceba63aab9a23938bf

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Surgical and physiological challenges in the development of left and right heart failure in rat models

Autor: Michael G. Katz, Anthony S. Fargnoli, Charles R. Bridges, Roger J. Hajjar, Sarah M. Gubara, Elena Chepurko

Publikováno v: Heart Fail Rev

Rodent surgical animal models of heart failure (HF) are critically important for understanding the proof of principle of the cellular alterations underlying the development of the disease as well as evaluating therapeutics. Robust, reproducible roden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9f4d3edf31dec196f6c56f77431868
https://doi.org/10.1007/s10741-019-09783-4

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Gene and protein-based therapies for improving cardiac performance and regeneration

Autor: Charles R. Bridges, Sarah M. Gubara, Roger J. Hajjar, Anthony S. Fargnoli, Michael G. Katz

Gene-based therapy is a relatively novel treatment which has the ability to target intracellular disease-specific manifestations in the setting of cardiac dysfunction. Gene transfer offers an option to treat the mutated or failing cardiomyocytes via

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e0d5afac7cc22ea186928d3d8645a45
https://doi.org/10.1016/b978-0-12-813706-2.00016-6

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Scar Size and Other Parameters for Tracking Left Ventricular Dysfunction after Induction of Myocardial Infarcts in Sheep (Ovis aries)

Autor: Anthony S. Fargnoli, Hylton P Gordon, Virginia L. Gillespie, Michael G. Katz, Roger J. Hajjar, Charles R. Bridges

Publikováno v: Comparative Medicine. 68:215-220

In humans, cardiovascular disease (CVD) is the most frequent cause of death worldwide. Myocardial infarction (MI) is a leading cause of heart failure due to myocardial impairment, yet the progression of the resultant dysfunction is often undetected a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a01f1dfd8797418c35bbd9932c2ca1
https://doi.org/10.30802/aalas-cm-17-000040

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Elektronická kniha

Educational Pathways for Black Students in Science, Engineering, and Medicine : Exploring Barriers and Possible Interventions: Proceedings of a Workshop

Autor: National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Policy and Global Affairs, Roundtable on Black Men and Black Women in Science, Engineering, and Medicine, Cato T. Laurencin, Paula Whitacre, Lynne M. Holden, Charles R. Bridges, Jr, Olujimi Ajijola

Academic preparation is critical to increase Black representation in Science, Engineering, and Medicine, but so, too, are such interrelated factors as providing mentoring and role models in sufficient numbers, adequately funding school and community

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