Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Charles Puerner"'
Autor:
Cecilia Gutierrez-Perez, Charles Puerner, Jane T. Jones, Sandeep Vellanki, Elisa M. Vesely, Mark A. Xatse, Andre F. C. Viera, Carissa P. Olsen, Keren O. Attiku, Steven Cardinale, Steven M. Kwasny, Narendran G-Dayanandan, Timothy J. Opperman, Robert A. Cramer
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Contemporary antifungal therapies utilized to treat filamentous fungal infections are inhibited by intrinsic and emerging drug resistance. Consequently, there is an urgent need to develop novel antifungal compounds that are effective against
Externí odkaz:
https://doaj.org/article/6c6f0dfdb29846f4968aadcda7933aa2
Autor:
Samuel L. Neff, Thomas H. Hampton, Charles Puerner, Liviu Cengher, Georgia Doing, Alexandra J. Lee, Katja Koeppen, Ambrose L. Cheung, Deborah A. Hogan, Robert A. Cramer, Bruce A. Stanton
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-14 (2022)
Abstract Researchers studying cystic fibrosis (CF) pathogens have produced numerous RNA-seq datasets which are available in the gene expression omnibus (GEO). Although these studies are publicly available, substantial computational expertise and manu
Externí odkaz:
https://doaj.org/article/5e30a2f3c1034ab18bf4061492bd63f8
Autor:
Charles Puerner, Nino Kukhaleishvili, Darren Thomson, Sebastien Schaub, Xavier Noblin, Agnese Seminara, Martine Bassilana, Robert A. Arkowitz
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-21 (2020)
Abstract Background The initial step of a number of human or plant fungal infections requires active penetration of host tissue. For example, active penetration of intestinal epithelia by Candida albicans is critical for dissemination from the gut in
Externí odkaz:
https://doaj.org/article/3f2cef2f2e494b8fbe277be4c769993a
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Hyphal tip growth is critical in a range of fungal pathogens, in particular for invasion into animal and plant tissues. In Candida albicans
Externí odkaz:
https://doaj.org/article/e15d3f154fd94939bf04a66a286562b8
Publikováno v:
Cell Reports, Vol 28, Iss 8, Pp 2231-2245.e5 (2019)
Summary: During symmetry breaking, the highly conserved Rho GTPase Cdc42 becomes stabilized at a defined site via an amplification process. However, little is known about how a new polarity site is established in an already asymmetric cell—a critic
Externí odkaz:
https://doaj.org/article/00991370df8e4abab87770d7998e4807
Publikováno v:
Current Opinion in Cell Biology
Current Opinion in Cell Biology, Elsevier, 2020, 62, pp.150-158. ⟨10.1016/j.ceb.2019.11.001⟩
Current Opinion in Cell Biology, 2020, 62, pp.150-158. ⟨10.1016/j.ceb.2019.11.001⟩
Current Opinion in Cell Biology, Elsevier, 2020, 62, pp.150-158. ⟨10.1016/j.ceb.2019.11.001⟩
Current Opinion in Cell Biology, 2020, 62, pp.150-158. ⟨10.1016/j.ceb.2019.11.001⟩
International audience; As the majority of fungi are nonmotile, polarized growth in response to an external signal enables them to search for nutrients and mating partners, and hence is crucial for survival and proliferation. Although the mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17df02a3ceb553a9a8fb1e333a6dc6e
https://doi.org/10.1016/j.ceb.2019.11.001
https://doi.org/10.1016/j.ceb.2019.11.001
Publikováno v:
mBio
mBio, 2021, 12 (5), ⟨10.1128/mBio.02528-21⟩
mBio, Vol 12, Iss 5 (2021)
mBio, American Society for Microbiology, 2021, 12 (5), ⟨10.1128/mBio.02528-21⟩
mBio, 2021, 12 (5), ⟨10.1128/mBio.02528-21⟩
mBio, Vol 12, Iss 5 (2021)
mBio, American Society for Microbiology, 2021, 12 (5), ⟨10.1128/mBio.02528-21⟩
In a number of elongated cells, such as fungal hyphae, a vesicle cluster is observed at the growing tip. This cluster, called a Spitzenkorper, has been suggested to act as a vesicle supply center, yet analysis of its function is challenging, as a maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1bd879f8ef21704655c09360aa053e
https://hal.science/hal-03453420
https://hal.science/hal-03453420
Autor:
David E. Stone, Xin Wang, Brian K. Kay, Charles Puerner, Rashida Abdul-Ganiyu, Robert A. Arkowitz, Leon A. Venegas
Publikováno v:
Science Signaling
Science Signaling, American Association for the Advancement of Science, 2021, 14 (682), ⟨10.1126/scisignal.abf4710⟩
Science Signaling, 2021, 14 (682), ⟨10.1126/scisignal.abf4710⟩
Science Signaling, American Association for the Advancement of Science, 2021, 14 (682), ⟨10.1126/scisignal.abf4710⟩
Science Signaling, 2021, 14 (682), ⟨10.1126/scisignal.abf4710⟩
International audience; Budding yeast cells interpret shallow pheromone gradients from cells of the opposite mating type, polarize their growth toward the pheromone source, and fuse at the chemotropic growth site. We previously proposed a determinist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb6c00fc11003664a37ef72b2ad20ae
https://hal.archives-ouvertes.fr/hal-03453411
https://hal.archives-ouvertes.fr/hal-03453411
Autor:
Darren D. Thomson, Xavier Noblin, Charles Puerner, Sébastien Schaub, Robert A. Arkowitz, Nino Kukhaleishvili, Martine Bassilana, Agnese Seminara
Publikováno v:
BMC Biology
BMC Biology, 2020, 18 (1), pp.122. ⟨10.1186/s12915-020-00833-0⟩
BMC Biology, Vol 18, Iss 1, Pp 1-21 (2020)
BMC Biology, BioMed Central, 2020, 18 (1), ⟨10.1186/s12915-020-00833-0⟩
Thomson, D 2020, ' Mechanical force-induced morphology changes in a human fungal pathogen ', BMC Biology . https://doi.org/10.1186/s12915-020-00833-0
BMC Biology, BioMed Central, 2020, 18 (1), pp.122. ⟨10.1186/s12915-020-00833-0⟩
BMC Biology, 2020, 18 (1), ⟨10.1186/s12915-020-00833-0⟩
BMC Biology, 2020, 18 (1), pp.122. ⟨10.1186/s12915-020-00833-0⟩
BMC Biology, Vol 18, Iss 1, Pp 1-21 (2020)
BMC Biology, BioMed Central, 2020, 18 (1), ⟨10.1186/s12915-020-00833-0⟩
Thomson, D 2020, ' Mechanical force-induced morphology changes in a human fungal pathogen ', BMC Biology . https://doi.org/10.1186/s12915-020-00833-0
BMC Biology, BioMed Central, 2020, 18 (1), pp.122. ⟨10.1186/s12915-020-00833-0⟩
BMC Biology, 2020, 18 (1), ⟨10.1186/s12915-020-00833-0⟩
Background The initial step of a number of human or plant fungal infections requires active penetration of host tissue. For example, active penetration of intestinal epithelia by Candida albicans is critical for dissemination from the gut into the bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7213b0feaf659af9b99b0fe1ad170fa4
https://www.hal.inserm.fr/inserm-02972162/document
https://www.hal.inserm.fr/inserm-02972162/document
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2019, 28 (8), pp.2231-2245.e5. ⟨10.1016/j.celrep.2019.07.062⟩
Cell Reports, Vol 28, Iss 8, Pp 2231-2245.e5 (2019)
Cell Reports, 2019, 28 (8), pp.2231-2245.e5. ⟨10.1016/j.celrep.2019.07.062⟩
Cell Reports, Elsevier Inc, 2019, 28 (8), pp.2231-2245.e5. ⟨10.1016/j.celrep.2019.07.062⟩
Cell Reports, Vol 28, Iss 8, Pp 2231-2245.e5 (2019)
Cell Reports, 2019, 28 (8), pp.2231-2245.e5. ⟨10.1016/j.celrep.2019.07.062⟩
Summary: During symmetry breaking, the highly conserved Rho GTPase Cdc42 becomes stabilized at a defined site via an amplification process. However, little is known about how a new polarity site is established in an already asymmetric cell—a critic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d4b39ce03099089b4607a2490f2457
https://doi.org/10.1016/j.celrep.2019.07.062
https://doi.org/10.1016/j.celrep.2019.07.062