PhTx3-4, a Spider Toxin Calcium Channel Blocker, Reduces NMDA-Induced Injury of the Retina

Autor: Nancy Scardua Binda, Charles Porto Petruceli Carayon, Rafael Mourão Agostini, Ana Cristina do Nascimento Pinheiro, Marta Nascimento Cordeiro, Marco Aurélio Romano Silva, Juliana Figueira Silva, Elizete Maria Rita Pereira, Claudio Antonio da Silva Junior, Célio José de Castro Junior, Andre Luiz Sena Guimarães, Marcus Vinicius Gomez

Publikováno v: Toxins, Vol 8, Iss 3, p 70 (2016)

The in vivo neuroprotective effect of PhTx3-4, a spider toxin N-P/Q calcium channel blocker, was studied in a rat model of NMDA-induced injury of the retina. NMDA (N-Methyl-d-Aspartate)-induced retinal injury in rats reduced the b-wave amplitude by 6

Externí odkaz: https://doaj.org/article/5e419d0628f64ddb8aa10a3e2507e105

PhTx3-4, a Spider Toxin Calcium Channel Blocker, Reduces NMDA-Induced Injury of the Retina.

Autor: Binda, Nancy Scardua¹ (AUTHOR) nancysbinda@yahoo.com.br, Petruceli Carayon, Charles Porto¹ (AUTHOR) charlespetruceli@hotmail.com, Agostini, Rafael Mourão¹ (AUTHOR) rafaelagostini@uol.com.br, do Nascimento Pinheiro, Ana Cristina¹ (AUTHOR) anapinheirofar@gmail.com, Cordeiro, Marta Nascimento² (AUTHOR) martadonascimento.phoneutria@gmail.com, Romano Silva, Marco Aurélio³ (AUTHOR) romanosilva@gmail.com, Silva, Juliana Figueira¹ (AUTHOR) jufigueira2003@yahoo.com.br, Rita Pereira, Elizete Maria¹ (AUTHOR) elizetemrpereira@yahoo.com.br, da Silva Junior, Claudio Antonio¹ (AUTHOR) claudiojunior.biologia@gmail.com, de Castro Junior, Célio José¹ (AUTHOR) celiojcjunior@gmail.com, Sena Guimarães, Andre Luiz⁴ (AUTHOR) andreluizguimaraes@gmail.com, Gomez, Marcus Vinicius¹ (AUTHOR) marcusvgomez@gmail.com

Publikováno v: Toxins. Mar2016, Vol. 8 Issue 3, p70-83. 14p. 2 Diagrams, 4 Graphs.