Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Charles P. Leonard"'
Autor:
Cheng Chen, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Sascha Dublin, Sophie P. Chung, John R. Horn, Kacie F. Bogar, Charles E. Leonard
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 2, Pp 326-337 (2023)
Abstract Antidepressants are associated with traumatic injury and are widely used with other medications. It remains unknown how drug–drug–drug interactions (3DIs) between antidepressants and two other drugs may impact potential injury risks asso
Externí odkaz:
https://doaj.org/article/2b2adebda87e4a949890c4d970be9f12
Autor:
Cheng Chen, Sean Hennessy, Colleen M. Brensinger, Emily K. Acton, Warren B. Bilker, Sophie P. Chung, Ghadeer K. Dawwas, John R. Horn, Todd A. Miano, Thanh Phuong Pham Nguyen, Charles E. Leonard
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Drug interactions involving benzodiazepines and related drugs (BZDs) are increasingly recognized as a contributor to increased risk of unintentional traumatic injury. Yet, it remains unknown to what extent drug interaction triads (3DIs) may
Externí odkaz:
https://doaj.org/article/863d6552694c41f8a3429b96706fcd46
Akademický článek
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Autor:
Charles E. Leonard, Yunfei Wang, Lina Asmar, Rachel Y. Lei, Kathryn T. Howell, Phyllis L. Henkenberns, Timothy K. Johnson, Tracy L. Hobart, Shannon P. Tole, Jane M. Kercher, Jodi L. Widner, Lora Barke, Terese Kaske, Dennis L. Carter
Publikováno v:
Cancer Medicine, Vol 10, Iss 20, Pp 7089-7100 (2021)
Abstract Purpose/Objective The primary objective is to examine patient self‐assessment of breast pain and cosmesis between three‐dimensional (3D‐CRT) versus intensity‐modulated radiotherapy (IMRT). The secondary objective is to evaluate any r
Externí odkaz:
https://doaj.org/article/df9360285429476a8a0b62eae7f1c431
Autor:
Charles E Leonard, Ainhoa Gomez-Lumbreras, Daniel C Malone, Kathleen M Andersen, G Caleb Alexander, Olga V Kravchenko, Richard D Boyce, Paul T Kocis, Lorenzo Villa Zapata, Malinda Tan, Hemalkumar Mehta
Publikováno v:
BMJ Open, Vol 12, Iss 12 (2022)
Objective The goal of this work is to evaluate if there is an increase in the risk of thromboembolic events (TEEs) due to concomitant exposure to dexamethasone and apixaban or rivaroxaban. Direct oral anticoagulants (DOACs), as well as corticosteroid
Externí odkaz:
https://doaj.org/article/47057c9f7a60469f81f911c441886621
Autor:
Emily K. Acton, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Todd A. Miano, Sascha Dublin, John R. Horn, Sophie Chung, Douglas J. Wiebe, Allison W. Willis, Charles E. Leonard
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Growing evidence suggests that drug interactions may be responsible for much of the known association between opioid use and unintentional traumatic injury. While prior research has focused on pairwise drug interactions, the role of higher-order (i.e
Externí odkaz:
https://doaj.org/article/8903caadb0e649668316aac9393704b4
Autor:
Charles E. Leonard, Colleen M. Brensinger, Ghadeer K. Dawwas, Rajat Deo, Warren B. Bilker, Samantha E. Soprano, Neil Dhopeshwarkar, James H. Flory, Zachary T. Bloomgarden, Joshua J. Gagne, Christina L. Aquilante, Stephen E. Kimmel, Sean Hennessy
Publikováno v:
Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-11 (2020)
Abstract Background The low cost of thiazolidinediones makes them a potentially valuable therapeutic option for the > 300 million economically disadvantaged persons worldwide with type 2 diabetes mellitus. Differential selectivity of thiazolidinedion
Externí odkaz:
https://doaj.org/article/7be6dabc839f4bdbb7f63feb7e38ed6d
Autor:
Thanh Phuong Pham Nguyen, Colleen M. Brensinger, Warren B. Bilker, Sean Hennessy, Charles E. Leonard
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 139, Iss , Pp 111559- (2021)
Background: In a previous drug-drug interaction (DDI) screening study intended to generate hypotheses, clopidogrel + either eszopiclone or zolpidem (vs. clopidogrel alone) were associated with serious bleeding. Objectives: To confirm or refute these
Externí odkaz:
https://doaj.org/article/64ba22f6162f4124987ca211c7770675
Autor:
Charles E. Leonard, Colleen M. Brensinger, Warren B. Bilker, Samantha E. Soprano, Neil Dhopeshwarkar, Todd E. H. Hecht, Scott E. Kasner, Edith A. Nutescu, Anne Holbrook, Matthew Carr, Darren M. Ashcroft, Cheng Chen, Sean Hennessy
Publikováno v:
Medicina, Vol 58, Iss 9, p 1171 (2022)
Background and Objectives: Warfarin and a skeletal muscle relaxant are co-treatments in nearly a quarter-million annual United States (US) office visits. Despite international calls to minimize patient harm arising from anticoagulant drug interaction
Externí odkaz:
https://doaj.org/article/257005ba3b6c4799a936b01b411a5469
Autor:
Charles E. Leonard, Shannon P. Tole, Michelle P. Turner, John P. Bennett, Kathryn T. Howell, Dennis L. Carter
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundThe following analysis explores clinicopathologic factors and the 12-gene Breast DCIS Score test result in order to better define an appropriate DCIS (ductal carcinoma in situ) population eligible for APBI (accelerated partial breast radiot
Externí odkaz:
https://doaj.org/article/cf4932b8165e46ee97e191baabbe8bfc