Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Charles P, Schmitt"'
Autor:
Jasmine A. Mack, Adam Burkholder, Farida S. Akhtari, John S. House, Ulla Sovio, Gordon C.S. Smith, Charles P. Schmitt, David C. Fargo, Janet E. Hall, Alison A. Motsinger-Reif
Publikováno v:
HGG Advances, Vol 6, Iss 1, Pp 100385- (2025)
Summary: Genetic factors related to pregnancy-related traits are understudied, especially in ancestrally diverse cohorts. To assess maternal contributions to hypertensive disorders of pregnancy (HDP), we performed a multi-ancestry genome-wide associa
Externí odkaz:
https://doaj.org/article/fe214fe7ea2846c3ac4af17ffeb4d26e
Autor:
Eunice Y. Lee, Wonson Choi, Adam B. Burkholder, Lalith Perera, Jasmine A. Mack, Frederick W. Miller, Michael B. Fessler, Donald N. Cook, Peer W. F. Karmaus, Hideki Nakano, Stavros Garantziotis, Jennifer H. Madenspacher, John S. House, Farida S. Akhtari, Charles S. Schmitt, David C. Fargo, Janet E. Hall, Alison A. Motsinger-Reif
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Asthma is a chronic disease of the airways that impairs normal breathing. The etiology of asthma is complex and involves multiple factors, including the environment and genetics, especially the distinct genetic architecture associated w
Externí odkaz:
https://doaj.org/article/b4c25f7994204ed68ceec9b548045815
Autor:
Montserrat Ayala-Ramirez, Nathaniel MacNell, Lucy E. McNamee, John A. McGrath, Farida S. Akhtari, Matthew D. Curry, Askia K. Dunnon, Michael B. Fessler, Stavros Garantziotis, Christine G. Parks, David C. Fargo, Charles P. Schmitt, Alison A. Motsinger-Reif, Janet E. Hall, Frederick W. Miller, Shepherd H. Schurman
Publikováno v:
Environment International, Vol 171, Iss , Pp 107687- (2023)
Background: Concentrated animal feeding operations (CAFOs) are a source of environmental pollution and have been associated with a variety of health outcomes. Immune-mediated diseases (IMD) are characterized by dysregulation of the normal immune resp
Externí odkaz:
https://doaj.org/article/6fd750625d1e400ea420cb3e832fe69d
Autor:
Jui-Hua Hsieh, Sue Nolte, Jon T. Hamm, Zicong Wang, Georgia K. Roberts, Charles P. Schmitt, Kristen R. Ryan
Publikováno v:
Toxics, Vol 11, Iss 5, p 407 (2023)
The embryonic zebrafish is a useful vertebrate model for assessing the effects of substances on growth and development. However, cross-laboratory developmental toxicity outcomes can vary and reported developmental defects in zebrafish may not be dire
Externí odkaz:
https://doaj.org/article/4a0478dfadd64bb1aa56137e9a3f5c9e
Autor:
Vickie R. Walker, Charles P. Schmitt, Mary S. Wolfe, Artur J. Nowak, Kuba Kulesza, Ashley R. Williams, Rob Shin, Jonathan Cohen, Dave Burch, Matthew D. Stout, Kelly A. Shipkowski, Andrew A. Rooney
Publikováno v:
Environment International, Vol 159, Iss , Pp 107025- (2022)
Introduction: There has been limited development and uptake of machine-learning methods to automate data extraction for literature-based assessments. Although advanced extraction approaches have been applied to some clinical research reviews, existin
Externí odkaz:
https://doaj.org/article/42972b504dc14de7b4308a659c2da38b
Autor:
Alexandre Borrel, Mike Conway, Sue Z Nolte, Aswani Unnikrishnan, Charles P Schmitt, Nicole C Kleinstreuer
Publikováno v:
Nucleic Acids Research.
Access to computationally based visualization tools to navigate chemical space has become more important due to the increasing size and diversity of publicly accessible databases, associated compendiums of high-throughput screening (HTS) results, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::743009bade3ffa326c48b044268fe472
https://doi.org/10.1093/nar/gkad380
https://doi.org/10.1093/nar/gkad380
Autor:
Farida S. Akhtari, Dillon Lloyd, Adam Burkholder, Xiaoran Tong, John S. House, Eunice Y. Lee, John Buse, Shepherd H. Schurman, David C. Fargo, Charles P. Schmitt, Janet Hall, Alison A. Motsinger-Reif
OBJECTIVE Environmental exposures may have greater predictive power for type 2 diabetes than polygenic scores (PGS). Studies examining environmental risk factors, however, have included only individuals with European ancestry, limiting the applicabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1466359c8d2c1393e7fddec02e40a4a
https://doi.org/10.2337/figshare.21399177.v1
https://doi.org/10.2337/figshare.21399177.v1
Autor:
Melissa E, Lowe, Farida S, Akhtari, Taylor A, Potter, David C, Fargo, Charles P, Schmitt, Shepherd H, Schurman, Kristin M, Eccles, Alison, Motsinger-Reif, Janet E, Hall, Kyle P, Messier
Publikováno v:
Journal of exposure scienceenvironmental epidemiology.
Autoimmune (AI) diseases appear to be a product of genetic predisposition and environmental triggers. Disruption of the skin barrier causes exacerbation of psoriasis/eczema. Oxidative stress is a mechanistic pathway for pathogenesis of the disease an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5a1e15cdabb4a47493aae6e72455756
https://pubmed.ncbi.nlm.nih.gov/36460922
https://pubmed.ncbi.nlm.nih.gov/36460922
Autor:
Eunice Y. Lee, Farida Akhtari, John S. House, Ross J. Simpson, Charles P. Schmitt, David C. Fargo, Shepherd H. Schurman, Janet E. Hall, Alison A. Motsinger-Reif
Publikováno v:
Environmental research. 212
While multiple factors are associated with cardiovascular disease (CVD), many environmental exposures that may contribute to CVD have not been examined. To understand environmental effects on cardiovascular health, we performed an exposome-wide assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abe8385bec850087c5322d76b1eba5ee
https://pubmed.ncbi.nlm.nih.gov/35605674
https://pubmed.ncbi.nlm.nih.gov/35605674
Autor:
Michael, Shoffner, Phillips, Owen, Javed, Mostafa, Brent, Lamm, Xiaoshu, Wang, Charles P, Schmitt, Stanley C, Ahalt
Publikováno v:
Clinical and translational science. 6(3)
Clinical data have tremendous value for translational research, but only if security and privacy concerns can be addressed satisfactorily. A collaboration of clinical and informatics teams, including RENCI, NC TraCS, UNC's School of Information and L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1ecff2746f0427b857892a00af42c4b
https://pubmed.ncbi.nlm.nih.gov/23751029
https://pubmed.ncbi.nlm.nih.gov/23751029