Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Charles P, Denaro"'
Publikováno v:
Current Trends in Internal Medicine. 4
Autor:
Alison M, Mudge, Charles P, Denaro, Adam C, Scott, Deborah, Meyers, Julie A, Adsett, Robert W, Mullins, Jessica M, Suna, John J, Atherton, Thomas H, Marwick, Paul, Scuffham, Peter, O'Rourke
Publikováno v:
JACC. Heart failure. 6(2)
This study sought to measure the impact on all-cause death or readmission of adding center-based exercise training (ET) to disease management programs for patients with a recent acute heart failure (HF) hospitalization.ET is recommended for patients
Publikováno v:
Clinical Pharmacology & Therapeutics. 59:624-635
Objectives A number of caffeine metabolite ratios (CMRs) have been proposed to measure CYP1A2 activity in vivo. The effect of liver disease on these ratios is not clear. The objective of this study was to determine the influence of liver disease on c
Publikováno v:
Clinical Pharmacology & Therapeutics. 59:284-296
Objectives A number of caffeine metabolite ratios have been proposed to measure CYP1A2 activity in vivo. The data to validate these ratios are scanty. The objective of this study was to validate urine caffeine metabolite ratios versus stable isotope-
Publikováno v:
Therapeutic drug monitoring. 20(1)
Simplified pharmacokinetic methods have been used to estimate caffeine clearance in subjects with liver disease. There is a need to have a reliable, easy to implement method for research and possible clinical use. This study evaluates the use of Baye
Publikováno v:
Clinical pharmacology and therapeutics. 58(6)
Caffeine is metabolized extensively (on average 80%) to paraxanthine. With regular caffeine consumption, average serum levels of paraxanthine are two thirds those of caffeine. Both caffeine and paraxanthine competitively and nonselectively inhibit ad
Publikováno v:
Clinical pharmacology and therapeutics. 53(1)
We propose a parametric pharmacokinetic-pharmacodynamic model for caffeine that quantifies the development of tolerance to the pressor effect of the drug and characterizes the mean behavior and inter-individual variation of both pharmacokinetics and
Publikováno v:
Clinical pharmacology and therapeutics. 50(3)
A stable isotope-labeled drug method was used to determine the absolute bioavailability and absorption kinetics of a transdermal nicotine-delivery system (TTS). TTSs are being developed as an adjunct to smoking-cessation therapy. Deuterium-labeled ni
Publikováno v:
Clinical pharmacology and therapeutics. 48(3)
Some recent epidemiologic studies have reported a nonlinear dose-response in the relationship between coffee consumption and health risks, such that the risks increase disproportionately to the increase in dose. Assuming caffeine contributes to the a
Autor:
Ian A. Scott, Charles P. Denaro, Annabel C. Hickey, Cameron Bennett, Alison M. Mudge, Daniela C. Sanders, Justine Thiele, Judy L. Flores
Publikováno v:
International Journal for Quality in Health Care; Aug2004, Vol. 16 Issue 4, p275-284, 10p