Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Charles Okeke"'
Publikováno v:
Proceedings, Vol 100, Iss 1, p 21 (2024)
Targeting cancer stem cells (CSCs) in anticancer discovery is very difficult due to the resistance of CSCs to conventional drugs, their low proliferation rate, improved DNA damage repair, and the overexpression of anti-apoptotic proteins and multidru
Externí odkaz:
https://doaj.org/article/4bd80125d0034e799b2e25ab725bd69d
Bioactivity-guided isolation of the antidiabetic principle in Pterocarpus Santalinoides leaf extract
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 59 (2023)
Abstract Pterocarpus santalinoides is used in Nigerian ethnomedicine to treat diabetes mellitus. This study aimed to establish the antidiabetic property of the plant, and isolate and characterize its active principle. Dried and pulverized leaves (500
Externí odkaz:
https://doaj.org/article/095c3b0899864839b2474b540bacf02f
Autor:
Emmanuel Ifeanyi Attah, Samson Chibuzo Ugwuagbo, Sampath Chinnam, Fabian Ifeanyi Eze, Charles Okeke Nnadi, Matthias Onyebuchi Agbo, Wilfred Obonga, Mithun Rudrapal, Sanjay G. Walode, Aatika Nizam, Ranjan Kumar Sahoo, Atul R. Bendale, Shubham J. Khairnar, Mohini R. Jagtap
Publikováno v:
Pharmacia, Vol 69, Iss 2, Pp 311-317 (2022)
Over the years, medicinal plants have been employed in the treatment of inflammation and related ailments. This study evaluated the anti-inflammatory potential of the aerial parts of S. brevipes. The extracts and fractions were further evaluated for
Externí odkaz:
https://doaj.org/article/680e28bd4a6f4378b45180af852e668d
Autor:
Damilola Jesuyajolu, Armstrong Nicholas, Charles Okeke, Chibuike Obi, Gamaliel Aremu, Kennedy Obiekwe, Ikegwuonu Obinna
Publikováno v:
Surgery in Practice and Science, Vol 10, Iss , Pp 100094- (2022)
Introduction: The more effort is put into work, the greater the chances of burnout. This is common among surgical personnel. We carried out this review study to determine the overall and per-specialty prevalence of burnout, and to identify the factor
Externí odkaz:
https://doaj.org/article/6ec4c946cf6847f6be2766aa4d20da35
Publikováno v:
Surgery in Practice and Science, Vol 9, Iss , Pp 100070- (2022)
Introduction: Nigeria is the most populous African country and primary healthcare makes up 88% of health facilities in Nigeria. The majority of these centers are unable to provide surgical care due to unequal distribution of equipment, doctors, and f
Externí odkaz:
https://doaj.org/article/46194a6bf57b463d91997635512a21d6
Publikováno v:
Molecules, Vol 23, Iss 5, p 1113 (2018)
As part of our research for new leads against human African trypanosomiasis (HAT), we report on a 3D-QSAR study for antitrypanosomal activity and cytotoxicity of aminosteroid-type alkaloids recently isolated from the African medicinal plant Holarrhen
Externí odkaz:
https://doaj.org/article/9bb9d4805a32455d9aa2a988059df314
Publikováno v:
Molecules, Vol 22, Iss 7, p 1129 (2017)
In our continued search for natural compounds with activity against Trypanosoma brucei, causative agent of human African trypanosomiasis (HAT, “sleeping sickness”), we have investigated extracts from the leaves and bark of the West African Holarr
Externí odkaz:
https://doaj.org/article/da90ec7e13344cd7a1d792b74359a707
Autor:
Ayoka, Thecla Okeahunwa, Nwachukwu, Ngwu, Ene, Aloysius Chinedu, Igwe, Chidi Uzoma, Nnadi, Charles Okeke
Publikováno v:
Indian Journal of Clinical Biochemistry; Apr2024, Vol. 39 Issue 2, p188-196, 9p
Autor:
Nnadi, Charles Okeke1,2 (AUTHOR) charles.nnadi@unn.edu.ng, Banda, Simnom Hope2 (AUTHOR) uzonwannemichael77@gmail.com, Uzonwanne, Michael Uchechukwu2 (AUTHOR), Didigwu, Obinna Kenneth1 (AUTHOR)
Publikováno v:
Proceedings (2504-3900). 2024, Vol. 100, p21. 2p.
Autor:
Charles Okeke Nnadi, Christian Chukwuagozie Ohama, Chinwe Mercy Onah, Jude Ebuka Ogbonna, Ozioma Jennifer Ikwuka, Chukwuebuka Moses Asogwa, Chibuike Ernest Ikwuka
Publikováno v:
Journal of Pharmaceutical Research International. :33-40
Aims: To evaluate the antiplasmodial activity of a trisdimethylamino pyrimidine derivative synthesized by indirect methylation of p-nitrophenylacetic acid via a substituted amine or amide derivative against Plasmodium berghei NK65 strain in an in viv