Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Charles N. Agoti"'
Autor:
Arnold W. Lambisia, Nickson Murunga, Martin Mutunga, Robinson Cheruiyot, Grace Maina, Timothy O. Makori, D. James Nokes, Charles N. Agoti
Publikováno v:
Gut Pathogens, Vol 16, Iss 1, Pp 1-8 (2024)
Abstract Background The non-pharmaceutical interventions (NPIs) implemented to curb the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) early in the coronavirus disease 2019 (COVID-19) pandemic, substantially disrupted the acti
Externí odkaz:
https://doaj.org/article/3de6812f786440dc9a1e1e457d49f18e
Autor:
D. Collins Owuor, Zaydah R. de Laurent, Bryan O. Nyawanda, Gideon O. Emukule, Rebecca Kondor, John R. Barnes, D. James Nokes, Charles N. Agoti, Sandra S. Chaves
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Influenza viruses undergo rapid evolutionary changes, which requires continuous surveillance to monitor for genetic and potential antigenic changes in circulating viruses that can guide control and prevention decision making. We sequenced an
Externí odkaz:
https://doaj.org/article/29e15b8e4c074563952b391663f94dbc
Autor:
Mike J. Mwanga, Arnold W. Lambisia, John Mwita Morobe, Nickson Murunga, Edidah Moraa, Leonard Ndwiga, Robinson Cheruiyot, Jennifer Musyoki, Martin Mutunga, Laura M. Guzman-Rincon, Charles Sande, Joseph Mwangangi, Philip Bejon, Lynette Isabella Ochola-Oyier, D. James Nokes, Charles N. Agoti, Joyce Nyiro, George Githinji
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 11, Pp 2376-2379 (2023)
We report a newly emerged SARS-CoV-2 Omicron subvariant FY.4 that has mutations Y451H in spike and P42L in open reading frame 3a proteins. FY.4 emergence coincided with increased SARS-CoV-2 cases in coastal Kenya during April–May 2023. Continued SA
Externí odkaz:
https://doaj.org/article/83c2a85256a44925a452598a06b31efa
Autor:
Melissa C. Kapulu, Esther Muthumbi, Edward Otieno, Omar Rossi, Pietro Ferruzzi, Francesca Necchi, Alessandra Acquaviva, Laura B. Martin, Benedict Orindi, Kennedy Mwai, Hillary Kibet, Alfred Mwanzu, Godfrey M. Bigogo, Jennifer R. Verani, Cecilia Mbae, Christopher Nyundo, Charles N. Agoti, Usman Nasir Nakakana, Valentino Conti, Philip Bejon, Samuel Kariuki, J. Anthony G. Scott, Francesca Micoli, Audino Podda
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundShigellosis mainly affects children under 5 years of age living in low- and middle-income countries, who are the target population for vaccination. There are, however, limited data available to define the appropriate timing for vaccine admi
Externí odkaz:
https://doaj.org/article/eb6544215e7348a1ae59375e0a39e3f1
Autor:
Grace Nabakooza, D. Collins Owuor, Zaydah R. de Laurent, Ronald Galiwango, Nicholas Owor, John T. Kayiwa, Daudi Jjingo, Charles N. Agoti, D. James Nokes, David P. Kateete, John M. Kitayimbwa, Simon D. W. Frost, Julius J. Lutwama
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Genetic characterisation of circulating influenza viruses directs annual vaccine strain selection and mitigation of infection spread. We used next-generation sequencing to locally generate whole genomes from 116 A(H1N1)pdm09 and 118 A(H3N2)
Externí odkaz:
https://doaj.org/article/3815ce0a46814b52a4389c513f8808ce
Autor:
Anderson F. Brito, Elizaveta Semenova, Gytis Dudas, Gabriel W. Hassler, Chaney C. Kalinich, Moritz U. G. Kraemer, Joses Ho, Houriiyah Tegally, George Githinji, Charles N. Agoti, Lucy E. Matkin, Charles Whittaker, Bulgarian SARS-CoV-2 sequencing group, Communicable Diseases Genomics Network (Australia and New Zealand), COVID-19 Impact Project, Danish Covid-19 Genome Consortium, Fiocruz COVID-19 Genomic Surveillance Network, GISAID core curation team, Network for Genomic Surveillance in South Africa (NGS-SA), Swiss SARS-CoV-2 Sequencing Consortium, Benjamin P. Howden, Vitali Sintchenko, Neta S. Zuckerman, Orna Mor, Heather M. Blankenship, Tulio de Oliveira, Raymond T. P. Lin, Marilda Mendonça Siqueira, Paola Cristina Resende, Ana Tereza R. Vasconcelos, Fernando R. Spilki, Renato Santana Aguiar, Ivailo Alexiev, Ivan N. Ivanov, Ivva Philipova, Christine V. F. Carrington, Nikita S. D. Sahadeo, Ben Branda, Céline Gurry, Sebastian Maurer-Stroh, Dhamari Naidoo, Karin J. von Eije, Mark D. Perkins, Maria van Kerkhove, Sarah C. Hill, Ester C. Sabino, Oliver G. Pybus, Christopher Dye, Samir Bhatt, Seth Flaxman, Marc A. Suchard, Nathan D. Grubaugh, Guy Baele, Nuno R. Faria
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
In this study, the authors provide a global overview of SARS-CoV-2 genome sequencing, and estimate the proportion of cases sequenced and time to genome upload. They identify disparities and highlight the need to strengthen surveillance in lower and m
Externí odkaz:
https://doaj.org/article/4ffaf8318aae4bf29738c1ee85ab524c
Autor:
Charles N. Agoti, Martin D. Curran, Nickson Murunga, Moses Ngari, Esther Muthumbi, Arnold W. Lambisia, Simon D. W. Frost, Barbara A. Blacklaws, D. James Nokes, Lydia N. Drumright
Publikováno v:
Gut Pathogens, Vol 14, Iss 1, Pp 1-12 (2022)
Abstract Background Kenya introduced Rotarix® (GlaxoSmithKline Biologicals, Rixensart, Belgium) vaccination into its national immunization programme beginning July 2014. The impact of this vaccination program on the local epidemiology of various kno
Externí odkaz:
https://doaj.org/article/e2ca3f6143754cc2bfd6cbada6a42bbf
Autor:
My V. T. Phan, Charles N. Agoti, Patrick K. Munywoki, Grieven P. Otieno, Mwanajuma Ngama, Paul Kellam, Matthew Cotten, D. James Nokes
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Pneumonia remains a major cause of mortality and morbidity. Most molecular diagnoses of viruses rely on polymerase chain reaction (PCR) assays that however can fail due to primer mismatch. We investigated the performance of routine virus dia
Externí odkaz:
https://doaj.org/article/b8674ec557a840ed853590141e4613ce
Autor:
Sophie Uyoga, Ambrose Agweyu, Rabia Aziza, Edwine Barasa, Benjamin Tsofa, Philip Bejon, Edward Otieno, Morris Ogero, John Ojal, Vincent Were, Samuel P. C. Brand, Ivy K. Kombe, Emelda A. Okiro, George M. Warimwe, Caroline Mburu, J. Anthony G. Scott, Ifedayo M. O. Adetifa, Charles N. Agoti, Lynette I. Ochola-Oyier, Patrick Amoth, Kadondi Kasera, Rashid Aman, Mercy Mwangangi, Matt J. Keeling, Wangari Ng’ang’a, D. James Nokes
Publikováno v:
Wellcome Open Research, Vol 6 (2022)
Policymakers in Africa need robust estimates of the current and future spread of SARS-CoV-2. We used national surveillance PCR test, serological survey and mobility data to develop and fit a county-specific transmission model for Kenya up to the end
Externí odkaz:
https://doaj.org/article/d7c6cef1f5d941efbd514c1f3c0a5ccc
Autor:
George Githinji, Zaydah R. de Laurent, Khadija Said Mohammed, Donwilliams O. Omuoyo, Peter M. Macharia, John M. Morobe, Edward Otieno, Samson M. Kinyanjui, Ambrose Agweyu, Eric Maitha, Ben Kitole, Thani Suleiman, Mohamed Mwakinangu, John Nyambu, John Otieno, Barke Salim, Kadondi Kasera, John Kiiru, Rashid Aman, Edwine Barasa, George Warimwe, Philip Bejon, Benjamin Tsofa, Lynette Isabella Ochola-Oyier, D. James Nokes, Charles N. Agoti
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
SARS-CoV-2 was first detected in Kenya in March 2020 and there was evidence of local transmission in the following months. Here, the authors characterise the early stages of the epidemic in coastal Kenya using phylogenetics and find evidence of multi
Externí odkaz:
https://doaj.org/article/a034766731d140dba3068aa4fac4efdf