Výsledky vyhledávání - "Charles McWherter"

Akademický článek

Arhalofenate acid inhibits monosodium urate crystal-induced inflammatory responses through activation of AMP-activated protein kinase (AMPK) signaling

Autor: Charles McWherter, Yun-Jung Choi, Ramon L. Serrano, Sushil K. Mahata, Robert Terkeltaub, Ru Liu-Bryan

Publikováno v: Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-11 (2018)

Abstract Background Arhalofenate acid, the active acid form of arhalofenate, is a non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand, with uricosuric activity via URAT1 inhibition. Phase II studies revealed decreased acute arth

Externí odkaz: https://doaj.org/article/d6553b490e6f4c16870ac89284cdd33e

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Seladelpar treatment of patients with primary biliary cholangitis (PBC) for 2 years improves the GLOBE PBC score and predicts improved transplant-free survival

Autor: Bettina Hansen, Elaine Watkins, Ke Yang, Yun-Jung Choi, Charles McWherter, Gideon Hirschfield

Publikováno v: Journal of Hepatology. 77:S322-S323

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c29aa15057f9ac5bc00aac3d6322ad0f
https://doi.org/10.1016/s0168-8278(22)01010-8

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Comparative fibrosis-reducing activities of farnesoid X receptor (FXR), peroxisome-proliferator activated receptor delta (PPAR) and thyroid hormone receptor (THR) agonists in the carbon tetrachloride mouse model

Autor: Edward Cable, Jeffrey Stebbins, Yun-Jung Choi, Jiangao Song, Prasad Manchem, Sanjay Pandy, Charles McWherter

Publikováno v: Journal of Hepatology. 77:S477

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2aa235da49ce63e2fae3268c8216ffb0
https://doi.org/10.1016/s0168-8278(22)01284-3

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Arhalofenate acid inhibits monosodium urate crystal-induced inflammatory responses through activation of AMP-activated protein kinase (AMPK) signaling

Autor: Sushil K. Mahata, Ramon L. Serrano, Ru Liu-Bryan, Charles McWherter, Robert Terkeltaub, Yun-Jung Choi

Publikováno v: Arthritis research & therapy, vol 20, iss 1
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-11 (2018)

Background Arhalofenate acid, the active acid form of arhalofenate, is a non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand, with uricosuric activity via URAT1 inhibition. Phase II studies revealed decreased acute arthritis fla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d24cdce91c70444bc6db924ab727bf
https://escholarship.org/uc/item/4mk81919

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FRI-329-Comparison of seladelpar and combinations with liraglutide or selonsertib for improvement of fibrosis and NASH in a diet-induced and biopsy-confirmed mouse model of NASH

Autor: Marc Hellerstein, Charles McWherter, Yun-Jung Choi, Jiangao Song, Jeff Johnson

Publikováno v: Journal of Hepatology. 70:e541

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74f762927e9637ee0b04de5c29cf31ca
https://doi.org/10.1016/s0618-8278(19)31070-9

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