Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Charles M. Schworer"'
Autor:
Irene Hinterseher, Charles M. Schworer, John H. Lillvis, Elizabeth Stahl, Robert Erdman, Zoran Gatalica, Gerard Tromp, Helena Kuivaniemi
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 11196-11212 (2015)
Our previous analysis using genome-wide microarray expression data revealed extreme overrepresentation of immune related genes belonging the Natural Killer (NK) Cell Mediated Cytotoxicity pathway (hsa04650) in human abdominal aortic aneurysm (AAA). W
Externí odkaz:
https://doaj.org/article/fca68a26d3f749c1b9b7eed1aae95e7c
Autor:
Evan J. Ryer, Kaitryn E. Ronning, Robert Erdman, Charles M. Schworer, James R. Elmore, Thomas C. Peeler, Christopher D. Nevius, John H. Lillvis, Robert P. Garvin, David P. Franklin, Helena Kuivaniemi, Gerard Tromp
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 11259-11275 (2015)
Abdominal aortic aneurysm (AAA) is a complex disorder that has a significant impact on the aging population. While both genetic and environmental risk factors have been implicated in AAA formation, the precise genetic markers involved and the factors
Externí odkaz:
https://doaj.org/article/d5e21841ea39413786511aa063d963eb
Publikováno v:
Cellular Signalling. 83:109977
Proliferation of Schwann cells during peripheral nerve development is stimulated by the heregulin/neuregulin family of growth factors expressed by neurons. However, for neonatal rat Schwann cells growing in culture, heregulins produce only a weak mit
Autor:
Larry A. Donoso, James R. Elmore, Glenn S. Gerhard, David J. Carey, William D. Bowen, Gerard Tromp, Kimberly Derr, Robert P. Garvin, Nikos Tapinos, Charles M. Schworer, Amy M. Boddy, Helena Kuivaniemi, Irene Hinterseher, David P. Franklin, Tamara R. Vrabec, John H Lillvis, Robert Erdman, Zoran Gatalica, Alicia Golden, John L. Gray
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 31:1653-1660
Objective— The goal of this study was to investigate the role of complement cascade genes in the pathobiology of human abdominal aortic aneurysms (AAAs). Methods and Results— Results of a genome-wide microarray expression profiling revealed 3274
Autor:
Charles M. Schworer, Edi Levi, Helena Kuivaniemi, Mary Higgins, Hong Jiang, Hui J. Li, Gerard Tromp, Maozhou Yang, Xiaohua Dai, Li Li, Anandita Arora, Neeraja Priyanka Annam, Xiao-Fan Wang, Jianbin Shen, Kezhong Zhang
Publikováno v:
Scientific Reports
TGF-β signaling plays critical roles in the pathogenesis of aneurysms; however, it is still unclear whether its role is protective or destructive. In this study, we investigate the role of SMAD3 in the pathogenesis of calcium chloride (CaCl2)-induce
Autor:
James R. Elmore, Charles M. Schworer, John H Lillvis, Christopher D. Nevius, Helena Kuivaniemi, Thomas C. Peeler, Gerard Tromp, Robert P. Garvin, Robert Erdman, Kaitryn E Ronning, Evan J. Ryer, David P. Franklin
Publikováno v:
International Journal of Molecular Sciences
Volume 16
Issue 5
Pages 11259-11275
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 11259-11275 (2015)
Volume 16
Issue 5
Pages 11259-11275
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 11259-11275 (2015)
Abdominal aortic aneurysm (AAA) is a complex disorder that has a significant impact on the aging population. While both genetic and environmental risk factors have been implicated in AAA formation, the precise genetic markers involved and the factors
Autor:
Joshua C. Anthony, Scot R. Kimball, Tracy G. Anthony, Leonard S. Jefferson, Stephen J. Crozier, Ali K. Reiter, Charles M. Schworer
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 285:E754-E762
The purpose of the study described herein was to investigate how the mammalian target of rapamycin (mTOR)-signaling pathway and eukaryotic initiation factor 2B (eIF2B) activity, both having key roles in the translational control of protein synthesis
Autor:
John H Lillvis, Robert Erdman, Elizabeth C. Stahl, Zoran Gatalica, Gerard Tromp, Charles M. Schworer, Irene Hinterseher, Helena Kuivaniemi
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 11196-11212 (2015)
Volume 16
Issue 5
Pages 11196-11212
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 11196-11212 (2015)
Volume 16
Issue 5
Pages 11196-11212
Our previous analysis using genome-wide microarray expression data revealed extreme overrepresentation of immune related genes belonging the Natural Killer (NK) Cell Mediated Cytotoxicity pathway (hsa04650) in human abdominal aortic aneurysm (AAA). W
Autor:
Evan J Ryer, Charles M Schworer, Robert P Garvin, Gerard Tromp, Kamell R Bernard-Eckroth, David P Franklin, James R Elmore, S H Kuivaniemi
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Background: The pathogenesis of abdominal aortic aneurysm (AAA) formation includes inflammation, vascular smooth muscle cell apoptosis, extracellular matrix degradation and oxidative stress. It is well established that multi-potent stem cells have an
Autor:
Joseph W. Mashni, Brian Seifman, Joseph V. Bonventre, Ping L. Zhang, Fan Lin, Venkata S. Sabbisetti, Kenneth Kernen, George S. Wilson, Mitual Amin, Jason Hafron, Charles M. Schworer, Stacy C. Wolforth, Timothy J. Geddes
Publikováno v:
International urology and nephrology. 46(2)
KIM-1 staining is upregulated in proximal tubule-derived renal cell carcinoma (RCC) including clear renal cell carcinoma and papillary renal cell carcinoma, but not in chromophobe RCC (distal tubular tumor). This study was designed to prospectively e