Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Charles M. Rubert Pérez"'
Autor:
Charles M. Rubert Pérez, Rachel L. Pride, Benjamin Y. Killam, Sara Rocus, William Schjerven, Gregory Kharas
Novel trisubstituted ethylenes, dimethyl, dimethoxy, and halogen ring-substituted isopropyl cyanophenylacrylates, RPhCH=C(CN)CO2CH(CH3)2 (where R is 2,3-dimethyl, 2,4-dimethyl, 2,5-dimethyl, 2,6-dimethyl, 3,4-dimethyl, 3,5-dimethyl, 2,3-dimethoxy, 2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b830e8b5622264759a92646ea586451
https://doi.org/10.26434/chemrxiv-2022-j78kp
https://doi.org/10.26434/chemrxiv-2022-j78kp
Autor:
Charles M. Rubert Pérez, Benjamin D. Cosgrove, Samuel I. Stupp, Adam T. Preslar, Russell D. Haynes, Thomas J. Meade, Charlotte H. Chen, M. Hussain Sangji, Helen M. Blau, Mark T. McClendon, Eduard Sleep
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Muscle stem cells are a potent cell population dedicated to efficacious skeletal muscle regeneration, but their therapeutic utility is currently limited by mode of delivery. We developed a cell delivery strategy based on a supramolecular liquid cryst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40c52f5bed0a924a6538de51ab2011e
https://doi.org/10.1073/pnas.1708142114
https://doi.org/10.1073/pnas.1708142114
Publikováno v:
ACS Biomaterials Science & Engineering
Fibroblast growth factor (FGF-2) is a multifunctional growth factor that has pleiotropic effects in different tissues and organs. In particular, FGF-2 has a special role in angiogenesis, an important process in development, wound healing, cell surviv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74805306c5dcda592053db18856ae911
https://pubmed.ncbi.nlm.nih.gov/28920077
https://pubmed.ncbi.nlm.nih.gov/28920077
Publikováno v:
Journal of the American Chemical Society. 135:3418-3422
A 27 amino acid collagen-based peptide (Hbyp3) was designed to radially display nine hydrophobic bipyridine moieties from a triple helical scaffold. Self-assembly of such functionalized triple helices led to the formation of micrometer-scaled disks w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563d0b261973893bd3a59198e749d9d8
https://doi.org/10.1021/ja307651e
https://doi.org/10.1021/ja307651e
Autor:
Charles M. Rubert Pérez, Samuel I. Stupp, Eduard Sleep, Sungsoo S. Lee, Faifan Tantakitti, Elena Pazos
Publikováno v:
Journal of the American Chemical Society
Silver nanoparticles have been of great interest as plasmonic substrates for sensing and imaging, catalysts, or antimicrobial systems. Their physical properties are strongly dependent on parameters that remain challenging to control such as size, che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814ad712db0db2a1bf5d446514947e8f
https://pubmed.ncbi.nlm.nih.gov/27103596
https://pubmed.ncbi.nlm.nih.gov/27103596
Publikováno v:
Chemical Biology & Drug Design. 79:260-269
Two molecular scaffolds were designed using the CAVEAT molecular design package to inhibit the oligomerization of protective antigen (PA63), a key protein component of anthrax toxin. The inhibitors were designed to prevent heptamerization of PA63 by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14b2a2f452b082e26b012109b0ad5bf4
https://doi.org/10.1111/j.1747-0285.2011.01285.x
https://doi.org/10.1111/j.1747-0285.2011.01285.x
Autor:
Edward Moreira Bahnson, Charles M. Rubert Pérez, Samuel I. Stupp, Qun Jiang, Timothy A. Pritts, Amanda W. Dombrowski, Melina R. Kibbe, Janet M. Vercammen, Courtney E. Morgan, Wulin Jiang, Nick D. Tsihlis, Vivek S. Prakash
Publikováno v:
ACS nano. 10(1)
Noncompressible torso hemorrhage is a leading cause of mortality in civilian and battlefield trauma. We sought to develop an i.v.-injectable, tissue factor (TF)-targeted nanotherapy to stop hemorrhage. Tissue factor was chosen as a target because it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1354b23e8d245efbfff1c971dc7cee9a
https://pubmed.ncbi.nlm.nih.gov/30481963
https://pubmed.ncbi.nlm.nih.gov/30481963
Publikováno v:
Macromolecular Bioscience. 11:1426-1431
Collagen peptide-based hydrogels are prepared and characterized for application in 3D cell growth. Physical hydrogels are formed by covalently linking a collagen-based peptide to an 8-arm poly(ethylene glycol) star polymer. The resulting viscoelastic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a472307d9fc9810ed4d57904a712c99
https://doi.org/10.1002/mabi.201100230
https://doi.org/10.1002/mabi.201100230
Publikováno v:
Chem. Commun.. 50:8174-8176
A hybrid hydrogel based on collagen-mimetic peptides has been designed with tunable thermosensitive properties. By changing the number of POG repeats within the collagen peptide sequence, the thermal stability of the triple helical physical crosslink
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1987268d22a80cffb3fdbcd904a6282a
https://doi.org/10.1039/c4cc03171g
https://doi.org/10.1039/c4cc03171g
Autor:
Samuel I. Stupp, Miranda So, Neel A. Mansukhani, Melina R. Kibbe, Charles M. Rubert Pérez, Erica B. Peters, Zheng Wang, Mazen Albaghdadi
Publikováno v:
Advanced Biosystems. 2:1700123
Co-assembled peptide amphiphile nanofibers designed to target atherosclerotic plaque and enhance cholesterol efflux are shown to encapsulate and deliver a liver X receptor agonist to increase efflux from murine macrophages in vitro. Fluorescence micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c2b2ffc664386e767e07164455154e
https://doi.org/10.1002/adbi.201700123
https://doi.org/10.1002/adbi.201700123