Zobrazeno 1 - 10 of 102 pro vyhledávání: '"Charles M. Gruber"'
2
Interactions in Rats Between the Nonsteroidal Antiinflammatory Drugs, Aspirin and Fenoprofen
Autor: Charles M. Gruber, Patricia Warrick, Alan Rubin
Publikováno v: Experimental Biology and Medicine. 147:599-607
We recently observed a pharmacodynamic interaction in healthy volunteers between two antiinflammatory agents, aspirin and fenoprofen. When subjects received both drugs the concentrations of fenoprofen in plasma were lowered significantly, compared to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502d63a72bb9a2ab610058fa37bd6873
https://doi.org/10.3181/00379727-147-38397
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3
Evaluating Interactions Between Fenoprofen and Propoxyphene: Analgesia and Adverse Reports by Postepisiotomy Patients
Autor: Charles M. Gruber
Publikováno v: The Journal of Clinical Pharmacology. 16:407-417
Groups of 30 postepisiotomy patients were administered single oral doses of fenoprofen calcium (0, 200, 400, or 600 mg acid equivalent) and/or propoxyphene napsylate (0, 50, 100, or 150 mg). The complete block design permits analysis of variance with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a24c1be87db8309f1212f75bd59d7d2
https://doi.org/10.1002/j.1552-4604.1976.tb02415.x
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4
A Comparative Analgesic Study of Propoxyphene, Fenoprofen, the Combination of Propoxyphene and Fenoprofen, Aspirin, and Placebo
Autor: Abraham Sunshine, Charles M. Gruber, R N Jean Slafta
Publikováno v: The Journal of Clinical Pharmacology. 18:556-563
Groups of 27 inpatients with moderate or severe postoperative, fracture, or somatic pain were given single oral doses of propoxyphene napsylate (P), fenoprofen calcium (F), combinations of P and F, aspirin, or placebo. The increasing rank order for e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948698b7bd8e1cbc8578d35920ce010f
https://doi.org/10.1002/j.1552-4604.1978.tb01585.x
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5
A PHARMACOKINETIC INTERACTION IN MAN BETWEEN PHENOBARBITONE AND FENOPROFEN, A NEW ANTI-INFLAMMATORY AGENT
Autor: Ridolfo As, Alan Rubin, L. Helleberg, Robert L. Wolen, Charles M. Gruber, Rodda Be
Publikováno v: British Journal of Clinical Pharmacology. 1:371-374
1 The effect of repeated administration of phenobarbitone on the plasma disposition of fenoprofen (±-2-(3-phenoxyphenyl) propionic acid) was investigated in rats and man. 2 The plasma elimination rate constants increased significantly and the rats e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601f1b2cf42e2e9260a651d26179d4db
https://doi.org/10.1111/j.1365-2125.1974.tb00271.x
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7
Determination of propoxyphene and norpropoxyphene by chemical ionization mass fragmentography
Autor: Robert L. Walen, Edgar A. Ziege, Charles M. Gruber
Publikováno v: Clinical Pharmacology & Therapeutics. 17:15-20
The kinetics of propoxyphene and its primary metabolite, norpropoxyphene, have been simultaneously re-evaluated in man by using gas-liquid chromatography/mass spectrometry, deuterium-labeled mass internal standards, and multiple ion monitoring. Plasm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::254906b5cbeda042c850cce49269c0e2
https://doi.org/10.1002/cpt197517115
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