Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Charles M Heldebrant"'
Autor:
Cristina Giachetti, James Gallarda, Charles M. Heldebrant, Richard Smith, Dale F. Hirschkorn, Michael P. Busch, Simone A. Glynn, Steven Kleinman, David Wright, Yongling Tu
Publikováno v:
Transfusion. 45:994-1002
BACKGROUND: It is important to characterize viral dynamics in early hepatitis C virus (HCV) infection to further our understanding of viral pathogenesis and the potential for secondary transmission in acute infection through blood transfusion or othe
Autor:
Todd M. Gierman, W. Kurt Roth, Gerold Zerlauth, Michael Chudy, Thomas Weimer, Celso Bianco, John Saldanha, Charles M. Heldebrant, Indira Hewlett, Guy Rautmann, Andrew Conrad, Susan L. Stramer, Barbee I. Whitaker
Publikováno v:
Biologicals. 31:153-159
The complexity of Nucleic acid Amplification Technology (NAT(1)), comprising sample preparation, amplification and detection methods, requires specific design considerations for both the laboratory and the procedures utilized in such testing. The pur
Autor:
David J. Wright, Richard T. Schumacher, Richard Smith, Charles M. Heldebrant, Patricia E. Garrett, Steven Kleinman, Peddada Lorraine B, Eberhard W. Fiebig, Andrew Conrad, Michael P. Busch, Bhupat D. Rawal
Publikováno v:
AIDS. 17:1871-1879
Objectives The characterization of primary HIV infection by the analysis of serial plasma samples from newly infected persons using multiple standard viral assays. Design A retrospective study involving two sets of archived samples from HIV-infected
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 28:295-302
Peripheral vascular disease is a common ailment of the aged and diabetic communities. As the numbers of these individuals increase, the need for therapeutic interventions will continue to grow. One of the possible therapies is the use of prostaglandi
Autor:
Michael P. Busch, Peddada Lorraine B, Brian T. Foley, Eric Delwart, Andrew Conrad, Richard Smith, Magdalena Magierowska, Charles M. Heldebrant, Maya Royz
Publikováno v:
AIDS. 16:189-195
Objective To measure HIV-1 quasispecies diversity in very recently infected male and female plasma donors. Methods HIV-1 RNA testing of blood and plasma donations was used to select anti HIV-1 antibody negative, HIV-1 RNA positive plasma samples from
Publikováno v:
Vox Sanguinis. 67:246-254
We report here the results of our evaluation of virus inactivation during the manufacturing steps of two intravenous immunoglobulin (IGIV) preparations. Virus inactivation and/or removal by processing steps, such as ethanol fractionation and polyethy
Autor:
Michael E. Nesheim, Alan R. Giles, Charles M Heldebrant, Hugh Hoogendoorn, Steven W Herring, David C. Stump
Publikováno v:
Thrombosis and Haemostasis. 63:476-481
SummaryParameters of the fibrinolytic system were studied in a primate model where the generation of thrombin was promoted in vivo. The procoagulant stimulus used was a combination of human factor Xa in combination with phosphatidylcholine/phos-phati
Autor:
Eberhard W, Fiebig, Charles M, Heldebrant, Richard I F, Smith, Andrew J, Conrad, Eric L, Delwart, Michael P, Busch
Publikováno v:
Journal of acquired immune deficiency syndromes (1999). 39(2)
Serial samples from source plasma donors with confirmed new HIV infection were investigated for low-level viremia (LLV) (ie,100 genome copies [cp]/mL) at time points preceding the period of steadily rising viremia above 100 cp/mL (ramp-up viremia). F
Publikováno v:
Thrombosis Research. 6:215-221
The number of heteropolysaccharide units of prothrombin has been reinvestigated and their distribution upon activation has been determined. The results of this study suggest that prothrombin contains three heteropolysaccharide units, and that upon ac
Publikováno v:
Annals of the New York Academy of Sciences. 240:43-61
A new method has been described for the isolation of factor VIII. The method results in a high yield of factor VIII that is homogeneous by several different criteria. The purified protein is very stable and is not dissociated in the presence of 1 M N