Learning from the Slime Mold: Dictyostelium and Human Disease

Autor: Charles L. Saxe

Publikováno v: The American Journal of Human Genetics. 65(1):25-30

When readers of this Journal think about Dictyostelium—rarely, if at all, I suspect—they may conjure up dim memories either of college laboratory demonstrations involving cell aggregation and cAMP or of watching the cells develop into tiny fruiti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0fc99b3933eb403e59620bde3038a58

Differential Distribution of cAMP Receptors cAR2 and cAR3 duringDictyosteliumDevelopment

Autor: Yimin Yu, Charles L. Saxe

Publikováno v: Developmental Biology. 173:353-356

Signal transduction via a family of cAMP receptor subtypes (cARs) is critical for proper development in the cellular slime moldDictyostelium.Genes encoding four related subtypes have been cloned and their expression, based on RNA accumulation, has be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5977295de11d7c2b7621444462533d6
https://doi.org/10.1006/dbio.1996.0030

Expression of a cAMP receptor gene of Dictyostelium and evidence for a multigene family

Autor: Ronald L. Johnson, Charles L. Saxe, Alan R. Kimmel, Peter N. Devreotes

Publikováno v: Genes & Development. 5:1-8

We have previously reported the cloning of cDNAs for a Dictyostelium cell-surface cAMP receptor that is a member of the family of G-protein-linked receptors. Here, we report the organization and the developmental expression of this cAMP receptor gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab12fb98b1a03ca13a3a6e0d66b59b4
https://doi.org/10.1101/gad.5.1.1

Contributors

Autor: John M. Abrams, John P. Adelman, Joseph L. Alcorn, Dario R. Alessi, Emil Alexov, Simon Alford, Kari Alitalo, James P. Allison, Steven C. Almo, Christelle Alory, Aymen Al-Shamkhani, Sally A. Amundson, Carl W. Anderson, Jannik N. Andersen, Peter Angel, Ettore Appella, William J. Arendshorst, Steve Arkinstall, Anjon Audhya, Joseph Avruch, Gary D. Bader, Cinzia Bagala, William E. Balch, Jesus Balsinde, Utpal Banerjee, David Barford, Dafna Bar-Sagi, Perry F. Bartlett, Philippe I.H. Bastiaens, Chiara Battelli, Linnea M. Baudhuin, Andrew J. Beavil, Rebecca L. Beavil, Joseph A. Beavo, Elsa Bello-Reuss, Stephen Bellum, Juan Carlos Izpisúa Belmonte, Craig B. Bennett, Jeffrey L. Benovic, Michael J. Berridge, Penny J. Beuning, Rashna Bhandari, Ananya Bhattacharya, Martin Biel, Vincent A. Bielinski, Hana Bilak, Lutz Birnbaumer, Geoff Birrell, Gail A. Bishop, Trillium Blackmer, Perry J. Blackshear, Christine Blattner, Mordecai P. Blaustein, Gary M. Bokoch, Lynda F. Bonewald, Marco Bonomi, Michelle A. Booden, Charles Boone, Martin D. Bootman, Johannes L. Bos, Jane M. Bradbury, Ralph A. Bradshaw, Anne R. Bresnick, Lena Brevnova, Ross I. Brinkworth, Michael S. Brown, Steven A. Brown, Anne Brunet, Robert Bucki, Robert D. Burgoyne, Janice E. Buss, Ronald A. Butow, Javier Capdevila, Ernesto Carafoli, Cathrine R. Carlson, Graham Carpenter, Juan J. Carrillo, Patrick J. Casey, William A. Catterall, Richard A. Cerione, Gianni Cesareni, Andrew C. Chan, Geoffrey Chang, Moses V. Chao, Harry Charbonneau, Philip Chen, Alan Cheng, Chris Chiu, Dar-chone Chow, Ted D. Chrisman, Anne Elisabeth Christensen, Jee Y. Chung, Grant C. Churchill, Aaron Ciechanover, Gino Cingolani, Sylvie Claeysen, Jean Closset, Shamshad Cockcroft, Patricia T.W. Cohen, Philip Cohen, Roger J. Colbran, Clay E.S. Comstock, Marco Conti, Jackie D. Corbin, Daniela Corda, Sabine Costagliola, Rick H. Cote, Shaun R. Coughlin, L. Ashley Cowart, Adrienne D. Cox, Mark S. Cragg, José L. Crespo, Claudia Crosio, Christopher Daly, Sami Damak, Mary Dasso, Michael David, Anthony J. Davis, Roger J. Davis, Richard N. Day, Eva Degerman, Warren L. DeLano, Mark L. Dell'Acqua, Emmanuèle Délot, Bruce Demple, Edward A. Dennis, John M. Denu, Anna A. DePaoli-Roach, Channing J. Der, Johan de Rooij, Frederic de Sauvage, Peter N. Devreotes, Valérie Dewaste, Robert B. Dickson, Becky A. Diebold, Pier Paolo Di Fiori, Maria Di Girolamo, Julie Diplexcito, Jack E. Dixon, Robert W. Doms, Daniel J. Donoghue, Russell F. Doolittle, Stein Ove Døskeland, Wolfgang R.G. Dostmann, Matthias K. Dreyer, Guo Guang Du, Keyong Du, Michael R. Duchen, William G. Dunphy, Joanne Durgan, Michael L. Dustin, Peter A. Edwards, Jackson G. Egen, Lee E. Eiden, Elaine A. Elion, Scott Emr, Othmar G. Engelhardt, Christophe Erneux, Peter J. Espenshade, Edward D. Esplin, B. Mark Evers, Joanne L. Eyles, Sheelagh Fame, Marilyn Farquhar, Robert Feil, Gui-Jie Feng, Stanley Fields, James J. Fiordalisi, Richard A. Firtel, Garret A. Fitzgerald, Andrew Flint, Marco Foiani, Barry Marc Forman, Albert J. Fornace, Sharron H. Francis, Günter Fritz, David A. Fruman, Antony Galione, Chris S. Gandhi, David L. Garbers, K. Christopher Garcia, Benjamin Geiger, Larry Gerace, Andrea Gerstner, Amato J. Giaccia, Michele Giannattasio, Vincent Giguère, Christopher K. Glass, Martin J. Glennie, Jennifer L. Glick, Joseph L. Goldstein, Venkatesh Gopal, Myriam Gorospe, Cedric Govaerts, Paul R. Graves, Patrick W. Gray, Irene Graziani, Douglas R. Green, Michael E. Greenberg, Iva Greenwald, Haihua Gu, Nuri Gueven, J. Silvio Gutkind, Jesper Z. Haeggström, Alan Hall, Michael N. Hall, Otto Haller, Heidi E. Hamm, Yusef A. Hannun, Carl A. Hansen, T. Kendall Harden, D. Grahame Hardie, Kiminori Hasegawa, Phillip T. Hawkins, Timothy A.J. Haystead, Xiao-lin He, Claus W. Heizmann, Carl-Henrik Heldin, Michelle L. Hermiston, Peter Herrlich, Elizabeth A. Hewat, Bertil Hille, Douglas J. Hilton, K.A. Hinchliffe, Steffan N. Ho, Su-Chin Ho, Mark Hochstrasser, Franz Hofmann, Christopher W. Hogue, Wim G.J. Hol, Jocelyn Holash, Robert A. Holmgren, Barry Honig, Bruce S. Hostager, Stevan R. Hubbard, Michael Huber, Tony Hunter, Anna Huttenlocher, Sarah G. Hymowitz, James N. Ihle, Jean-Luc Imler, R.F. Irvine, Ehud Y. Isacoff, Xavier Iturrioz, Lars F. Iversen, Ravi Iyengar, Stephen P. Jackson, Lily Yeh Jan, Fabiola Janiak-Spens, Paul A. Janmey, Peter Gildsig Jansen, Sophie Jarriault, Jonathan A. Javitch, Elwood V. Jensen, Kristen Jepsen, E. Yvonne Jones, Katherine A. Jones, J. Dedrick Jordan, Jomon Joseph, Louis B. Justement, Yariv Kafri, Richard A. Kahn, Shin W. Kang, Arthur Karlin, Heidi R. Kast-Woelbern, Randal J. Kaufman, Andrius Kazlauskas, James H. Keen, Rolf Kemler, Bruce E. Kemp, Mary B. Kennedy, Matthew A. Kennedy, Ushio Kikkawa, Albert H. Kim, Soo-A Kim, Sung-Hou Kim, Youngjoo Kim, Kirst King-Jones, Chris Kintner, Saul Kivimäe, Claude B. Klee, Rüdiger Klein, Thomas Kleppisch, Steven A. Kliewer, Richard A. Klinghoffer, Juergen A. Knoblich, Bostjan Kobe, George Kochs, Monica Kong-Beltran, Rolf König, Albert C. Koong, Murray Korc, Daniel Kornitzer, Anthony A. Kossiakoff, Jun Kotera, M.V. Kovalenko, Tohru Kozasa, Sergei Kozlov, Keith G. Kozminski, Sonja Krugmann, John Kuriyan, Riki Kurokawa, Peter D. Kwong, Wi S. Lai, Elise Lamar, Millard H. Lambert, David G. Lambright, Doron Lancet, Reiko Landry, Wallace Y. Langdon, Lorene K. Langeberg, Paul Lasko, Vaughn Latham, Martin F. Lavin, Kevin A. Lease, Hakon Leffler, Mark A. Lemmon, Ann E. Leonard, Alexander Levitzki, Hong-Jun Liao, Lucy Liaw, Giordano Liberi, Heiko Lickert, Robert C. Liddington, Thomas M. Lincoln, Jürgen U. Linder, Maurine E. Linder, Hui Liu, Zhengchang Liu, Marja K. Lohela, Sarah H. Louie, Deirdre K. Luttrell, Louis M. Luttrell, Karen M. Lyons, S. Lance Macaulay, Michael Maceyka, Thomas Maciag, Fernando Macian, Carol MacKintosh, David H. MacLennan, Nadir A. Mahmood, Craig C. Malbon, Sohail Malik, Orna Man, Carol L. Manahan, Anna Mandinova, Vincent C. Manganiello, James L. Manley, Matthias Mann, Gerald Manning, Ed Manser, Marta Margeta-Mitrovic, Robert F. Margolskee, Julia Marinissen, Roy A. Mariuzza, Mina D. Marmor, G. Steven Martin, Karen H. Martin, Sergio E. Martinez, Michael B. Mathews, Bruce J. Mayer, Mark L. Mayer, Maria R. Mazzoni, Frank McCormick, Clare H. McGowan, Melissa M. McKay, Wallace L. McKeehan, Alison J. McLean, Anthony R. Means, Ruedi Meili, Jingwei Meng, Mark Merchant, Frank Mercurio, Graeme Milligan, Guo-Li Ming, Daniel L. Minor, Nadeem Moghal, Neils Peter H. Møller, Marco Mongillo, Marc Montminy, Randall T. Moon, Richard I. Morimoto, Stephen E. Moss, Helen R. Mott, Carla Mouta, Marco Muda, Marc C. Mumby, Gretchen A. Murphy, Marco Muzi-Falconi, Raghavendra Nagaraj, Stefan R. Nahorski, Angus C. Nairn, Piers Nash, Benjamin G. Neel, Alexandra C. Newton, Yasutomi Nishizuka, Joseph P. Noel, Ellen A.A. Nollen, Irene M.A. Nooren, Rodney O'Connor, Stefan Offermanns, Tsviya Olender, Shao-En Ong, Darerca Owen, Lisa J. Pagliari, Lily Pao, John Papaconstantinou, Leonardo Pardo, Hay-Oak Park, Young Chul Park, Peter J. Parker, J. Thomas Parsons, J.M. Passner, Tony Pawson, Achille Pelliccioli, J. Regino Perez-Polo, Norbert Perrimon, Fabrice G. Petite, Emmanuel Petroulakis, Samuel L. Pfaff, Jacob Piehler, Linda J. Pike, Michael J. Pinkoski, Fiona J. Pixley, Paolo Plevani, Mu-ming Poo, Tullioi Pozzan, Stephen M. Prescott, Igor Prudovsky, James W. Putney, Thomas Radimerski, Elzbieta Radzio-Andzelm, Prahlad T. Ram, Lucia Rameh, Danica Ramljak, Barbara Ranscht, Anjana Rao, Carol J. Raport, Jacqueline D. Reeves, Holger Rehman, Trevor W. Reichman, Eric Reiter, Michael A. Resnick, Michael Reth, Sue Goo Rhee, Joel D. Richter, Rodney L. Rietze, James M. Rini, Jürgen A. Ripperger, Josep Rizo, Janet D. Robishaw, H. Llewelyn Roderick, Robert G. Roeder, Larry R. Rohrschneider, David Ron, Michael G. Rosenfeld, Hans Rosenfeldt, Kent L. Rossman, Christopher B. Roth, Markus G. Rudolph, Anja Ruppelt, Lino Saez, Thomas P. Sakmar, Guy S. Salvesen, Paolo Sassone-Corsi, Charles L. Saxe, Beat W. Schäfer, Ueli Schibler, Christian W. Schindler, Tobias Schmelzle, Sandra L. Schmid, Anja Schmidt, Eric F. Schmidt, Gideon Schreiber, Joachim E. Schultz, Beat Schwaller, Klaus Schwamborn, Thue Schwartz, William F. Schwindinger, Giorgio Scita, John D. Scott, Shaun Scott, Thomas Seebeck, Charles N. Serhan, John B. Shabb, Andrey S. Shaw, Stephen B. Shears, Shirish Shenolikar, Lei Shi, Chanseok Shin, Kazuhiro Shiozaki, Kevan M. Shokat, Trevor J. Shuttleworth, David P. Siderovski, Steven A. Siegelbaum, Adam M. Silverstein, Robert H. Singer, Michael K. Skinner, Jill K. Slack-Davis, Stephen J. Smerdon, Graeme C.M. Smith, Guillaume Smits, Sarah M. Smolik, Jessica E. Smotrys, Emer M. Smyth, Jason T. Snyder, Naoko Sogame, Raffaella Soldi, John Sondek, Nahum Sonenberg, Erica Dutil Sonneberg, Lindsay G. Sparrow, Sarah Spiegel, Stephen R. Sprang, Deepak Srivastava, Robyn L. Stanfield, E. Richard Stanley, Deborah J. Stauber, Christopher Stefan, Lena Stenson-Holst, Len Stephens, Paul W. Sternberg, Paul C. Sternweis, Ruth Steward, John T. Stickney, Andrew W. Stoker, Stephen M. Strittmatter, Beth E. Stronach, Roland K. Strong, Robert M. Stroud, Thomas C. Südhof, Roger K. Sunahara, Brian J. Sutton, Sipeki Szabolcs, Xiao-Bo Tang, Kjetil Taskén, Hisashi Tatebe, Servane Tauszig-Delamasure, Colin W. Taylor, Garry L. Taylor, Laura J. Taylor, Susan S. Taylor, George Thomas, Robert P. Thomas, E. Brad Thompson, Michael J. Thompson, Janet M. Thornton, Carl S. Thummel, Hideaki Togashi, Amy Hin Yan Tong, Nicholas K. Tonks, Peter Tontonoz, M.K. Topham, Knut Martin Torgersen, Hien Tran, Michel L. Tremblay, Ming-Jer Tsai, Sophia Y. Tsai, Susan Tsunoda, Stewart Turley, Darren Tyson, Robert L. Van Etten, Gilbert Vassart, Peter J. Verveer, Virginie Vlaeminck, Abraham M. de Vos, Ty C. Voss, Robert Walczak, Graham C. Walker, John C. Walker, Gernot Walter, Mark R. Walter, Fen Wang, Jean Y.J. Wang, Weiru Wang, Richard J. Ward, Philip Wedegaertner, Christian Wehrle, Arthur Weiss, Jamie L. Weiss, Alan Wells, Claudia Werner, Ann H. West, Marie C. Weston, John K. Westwick, Anders Wetterholm, Morris F. White, Malcolm Whitman, Matt R. Whorton, Christian Wiesmann, Roger L. Williams, William D. Willis, Timothy M. Willson, Ian A. Wilson, Ofer Wiser, Matthew J. Wishart, Alfred Wittinghofer, James R. Woodgett, David K. Worthylake, Jeffrey L. Wrana, Hao Wu, Yijin Xiao, H. Eric Xu, Yan Xu, Zheng Xu, Michael B. Yaffe, Kenneth M. Yamada, Seun-Ah Yang, Wannian Yang, Yosef Yarden, Hong Ye, Weilan Ye, Todd O. Yeates, Helen L. Yin, John D. York, Edgar C. Young, Kenneth W. Young, Matthew A. Young, Michael W. Young, Minmin Yu, Nathan R. Zaccai, Manuela Zaccolo, Eli Zamir, Mark von Zastrow, Chao Zhang, Xuewu Zhang, Zhong-Yin Zhang, Wenhong Zhou, Roya Zoraghi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8de55d9ade3047617aeaa3478f4b703f
https://doi.org/10.1016/b978-012124546-7/50358-2

Signals that make you different: receptor-mediated signal transduction in early development

Autor: Charles L. Saxe

Publikováno v: Zygote (Cambridge, England). 2(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff91e5ed475dccbc307ba72456351cf9
https://pubmed.ncbi.nlm.nih.gov/8785675