Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Charles L. Chaffin"'
Autor:
Lori R. Bernstein, Amelia C. L. Mackenzie, Charles L. Chaffin, Se-Jin Lee, Duane C. Kraemer, Istvan Merchenthaler
Publikováno v:
Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Elevated FSH often occurs in women of advanced maternal age (AMA, age ≥ 35) and in infertility patients undergoing controlled ovarian stimulation (COS). There is controversy on whether high endogenous FSH contributes to infertil
Externí odkaz:
https://doaj.org/article/7db6bcaa8c2f493cab90c5b1c30b9ec8
Autor:
Catherine A. VandeVoort, Chin-Shang Li, John P. Capitanio, Cheryl K. Walker, Charles L. Chaffin
Publikováno v:
Developmental psychobiology. 60(6)
Growing evidence identifies maternal adiposity as a potentially modifiable risk factor for adverse neurodevelopment. This retrospective cohort analysis examined whether maternal prepregnancy adiposity and gestational weight gain were associated with
Autor:
Charles L. Chaffin, Se-Jin Lee, Lori R. Bernstein, Istvan Merchenthaler, Amelia C.L. Mackenzie
Publikováno v:
Endocrinology. 157(3)
Women of advanced maternal age (AMA) (age ≥ 35) have increased rates of infertility, miscarriages, and trisomic pregnancies. Collectively these conditions are called “egg infertility.” A root cause of egg infertility is increased rates of oocyt
Publikováno v:
Experimental Biology and Medicine. 238:539-548
Ovarian function has a great deal of functional overlap between species; antral follicles grow in response to FSH, ovulation involves proteolysis, and the steroidogenic pathway is largely the same. However, embedded in these similarities are importan
Publikováno v:
Endocrinology. 153:5535-5545
Follicular somatic cells (mural granulosa cells and cumulus cells) and the oocyte communicate through paracrine interactions and through direct gap junctions between oocyte and cumulus cells. Considering that mural and cumulus cells arise through a c
Publikováno v:
Fertility and Sterility. 93:1421-1429
Objective To determine intrafollicular hormone levels and characterize the mRNA expression of the insulin-like growth factor (IGF) receptors, IGF binding proteins (IGFBP), and pregnancy-associated plasma protein-A (PAPP-A) in granulosa cells before a
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 296:E1392-E1399
During hormonally induced ovarian follicle growth, granulosa cell proliferation increases and returns to baseline prior to the administration of an ovulatory stimulus. Several key genes appear to follow a similar pattern, including the luteinizing ho
Autor:
Jenna K. Nyholt de Prada, Catherine A. VandeVoort, Keith E. Latham, Young S. Lee, Charles L. Chaffin
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 296:E1049-E1058
The developmental competence of in vitro-matured (IVM) rhesus macaque cumulus oocyte complexes (COCs) is deficient compared with in vivo-matured (IVM) oocytes. To improve oocyte quality and subsequent embryo development following IVM, culture conditi
Autor:
Muraly Puttabyatappa, Charles L. Chaffin, K.N. Fru, Catherine A. VandeVoort, Mary Cherian-Shaw
Publikováno v:
Human Reproduction. 22:1247-1252
BACKGROUND: This study seeks to clarify cell cycle dynamics of granulosa cells following hCG and elucidate the expression of epidermal growth factor (EGF)-like ligands during luteinization. METHODS: Granulosa cells were obtained from rhesus macaques
Publikováno v:
Biology of Reproduction. 75:568-574
Ovulation and luteal formation in primates are associated with the sustained synthesis of progesterone. The observed high intrafollicular concentrations of progesterone during the periovulatory interval raise the possibility that this steroid serves