Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Charles L. Bidgood"'
Autor:
Charles L. Bidgood, Lisa K. Philp, Anja Rockstroh, Melanie Lehman, Colleen C. Nelson, Martin C. Sadowski, Jennifer H. Gunter
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-12 (2024)
Abstract Metabolic reprogramming and energetic rewiring are hallmarks of cancer that fuel disease progression and facilitate therapy evasion. The remodelling of oxidative phosphorylation and enhanced lipogenesis have previously been characterised as
Externí odkaz:
https://doaj.org/article/5811d1732bff4d279de2e125b6da8d03
Autor:
Reuben S.E. Young, Andrew P. Bowman, Elizabeth D. Williams, Kaylyn D. Tousignant, Charles L. Bidgood, Venkateswara R. Narreddula, Rajesh Gupta, David L. Marshall, Berwyck L.J. Poad, Colleen C. Nelson, Shane R. Ellis, Ron M.A. Heeren, Martin C. Sadowski, Stephen J. Blanksby
Publikováno v:
Cell Reports, Vol 34, Iss 6, Pp 108738- (2021)
Summary: Canonical fatty acid metabolism describes specific enzyme-substrate interactions that result in products with well-defined chain lengths, degree(s), and positions of unsaturation. Deep profiling of lipids across a range of prostate cancer ce
Externí odkaz:
https://doaj.org/article/27b8a1a8bbb5417e805cadd5a720a7a8
Autor:
Charles L. Bidgood, Michelle S. Libério, Martin C. Sadowski, Melanie Lehman, Colleen C. Nelson, John D. Wade, Jennifer H. Gunter, Lisa Philp, Anja Rockstroh, Stephen McPherson, Laszlo Otvos, Gregor Tevz, Nenad Bartonicek, Atefeh Taherian Fard
Publikováno v:
Philp, Lisa K; Rockstroh, Anja; Sadowski, Martin C; Taherian Fard, Atefeh; Lehman, Melanie; Tevz, Gregor; Libério, Michelle S; Bidgood, Charles L; Gunter, Jennifer H; McPherson, Stephen; Bartonicek, Nenad; Wade, John D; Otvos, Laszlo; Nelson, Colleen C (2021). Leptin antagonism inhibits prostate cancer xenograft growth and progression. Endocrine-related cancer, 28(5), pp. 353-375. BioScientifica Ltd. 10.1530/ERC-20-0405
Hyperleptinaemia is a well-established therapeutic side effect of drugs inhibiting the androgen axis in prostate cancer (PCa), including main stay androgen deprivation therapy (ADT) and androgen targeted therapies (ATT). Given significant crossover b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ea4121f76d184e85e5e2e7dda6b1d9
https://boris.unibe.ch/161800/1/33794502.pdf
https://boris.unibe.ch/161800/1/33794502.pdf
Autor:
David L. Marshall, Andrew P. Bowman, Reuben S. E. Young, Rajesh Gupta, Colleen C. Nelson, Shane R. Ellis, Ron M. A. Heeren, Kaylyn D. Tousignant, Martin C. Sadowski, Charles L. Bidgood, Stephen J. Blanksby, Venkateswara R. Narreddula, Elizabeth D. Williams, Berwyck L. J. Poad
Publikováno v:
Cell Reports, Vol 34, Iss 6, Pp 108738-(2021)
Young, Reuben S E; Bowman, Andrew P; Williams, Elizabeth D; Tousignant, Kaylyn D; Bidgood, Charles L; Narreddula, Venkateswara R; Gupta, Rajesh; Marshall, David L; Poad, Berwyck L J; Nelson, Colleen C; Ellis, Shane R; Heeren, Ron M A; Sadowski, Martin C; Blanksby, Stephen J (2021). Apocryphal FADS2 activity promotes fatty acid diversification in cancer. Cell reports, 34(6), p. 108738. Cell Press 10.1016/j.celrep.2021.108738
Cell Reports, 34(6):108738. Cell Press
Young, Reuben S E; Bowman, Andrew P; Williams, Elizabeth D; Tousignant, Kaylyn D; Bidgood, Charles L; Narreddula, Venkateswara R; Gupta, Rajesh; Marshall, David L; Poad, Berwyck L J; Nelson, Colleen C; Ellis, Shane R; Heeren, Ron M A; Sadowski, Martin C; Blanksby, Stephen J (2021). Apocryphal FADS2 activity promotes fatty acid diversification in cancer. Cell reports, 34(6), p. 108738. Cell Press 10.1016/j.celrep.2021.108738
Cell Reports, 34(6):108738. Cell Press
Canonical fatty acid metabolism describes specific enzyme-substrate interactions that result in products with well-defined chain lengths, degree(s), and positions of unsaturation. Deep profiling of lipids across a range of prostate cancer cell lines
Autor:
Rohan A. Davis, Martin C. Sadowski, Jennifer H. Gunter, Charles L. Bidgood, Rohitesh Kumar, Claire Levrier, Colleen C. Nelson
Publikováno v:
Journal of natural products. 83(8)
The spirooxepinisoxazoline alkaloid psammaplysin F (1) was selected as a scaffold for the generation of a unique screening library for both drug discovery and chemical biology research. Large-scale extraction and isolation chemistry was performed on
Autor:
Martin C. Sadowski, Venkateswara R. Narreddula, Elizabeth D. Williams, Berwyck L. J. Poad, Rajesh Gupta, Charles L. Bidgood, Reuben S. E. Young, Shane R. Ellis, David L. Marshall, Ron M. A. Heeren, Andrew P. Bowman, Stephen J. Blanksby, Colleen C. Nelson, Kaylyn D. Tousignant
Fatty acid (FA) modifications, such as enzymatic desaturation and elongation, have long been thought to involve sequential and highly specific enzyme-substrate interactions, which result in canonical products that are well-defined in their chain leng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ecc6b36ae7db4a39a4e4d074c51c056
https://doi.org/10.1101/2020.06.07.139089
https://doi.org/10.1101/2020.06.07.139089