Zobrazeno 1 - 10
of 282
pro vyhledávání: '"Charles L. Bevins"'
Autor:
Douglas T Akahoshi, Dean E Natwick, Weirong Yuan, Wuyuan Lu, Sean R Collins, Charles L Bevins
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011200 (2023)
In the mammalian intestine, flagellar motility can provide microbes competitive advantage, but also threatens the spatial segregation established by the host at the epithelial surface. Unlike microbicidal defensins, previous studies indicated that th
Externí odkaz:
https://doaj.org/article/830cdc9a147842cbb40499ee4cd20a3a
Autor:
Eric B. Nonnecke, Patricia A. Castillo, Douglas T. Akahoshi, Stephanie M. Goley, Charles L. Bevins, Bo Lönnerdal
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Intelectins are carbohydrate-binding proteins implicated in innate immunity and highly conserved across chordate evolution, including both ascidians and humans. Human intelectin-1 (ITLN1) is highly abundant within the intestinal mucosa and binds micr
Externí odkaz:
https://doaj.org/article/9797383244704401aae3d7b277bc9394
Autor:
Faisal Almalki, Eric B. Nonnecke, Patricia A. Castillo, Alex Bevin-Holder, Kristian K. Ullrich, Bo Lönnerdal, Linda Odenthal-Hesse, Charles L. Bevins, Edward J. Hollox
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Intelectins are a family of multimeric secreted proteins that bind microbe-specific glycans. Both genetic and functional studies have suggested that intelectins have an important role in innate immunity and are involved in the etiology of va
Externí odkaz:
https://doaj.org/article/14012eaa25dc49de85047a15b875a01c
Autor:
Eric B. Nonnecke, Patricia A. Castillo, Amanda E. Dugan, Faisal Almalki, Mark A. Underwood, Carol A. De La Motte, Weirong Yuan, Wuyuan Lu, Bo Shen, Malin E. V. Johansson, Laura L. Kiessling, Edward J. Hollox, Bo Lönnerdal, Charles L. Bevins
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Intelectins are ancient carbohydrate binding proteins, spanning chordate evolution and implicated in multiple human diseases. Previous GWAS have linked SNPs in ITLN1 (also known as omentin) with susceptibility to Crohn's disease (CD); howeve
Externí odkaz:
https://doaj.org/article/a9f7b8fb0d704bc08db78ccd4cacb4d3
Autor:
Douglas T. Akahoshi, Charles L. Bevins
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Many bacteria and other microbes achieve locomotion via flagella, which are organelles that function as a swimming motor. Depending on the environment, flagellar motility can serve a variety of beneficial functions and confer a fitness advantage. For
Externí odkaz:
https://doaj.org/article/4e3dc6502c0e43e6a2aa8d8dc6e8c9b1
Autor:
Patricia A. Castillo, Eric B. Nonnecke, Daniel T. Ossorio, Michelle T. N. Tran, Stephanie M. Goley, Bo Lönnerdal, Mark A. Underwood, Charles L. Bevins
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Abstract Abundant evidence from many laboratories supports the premise that α-defensin peptides secreted from Paneth cells are key mediators of host-microbe interactions in the small intestine that contribute to host defense and homeostasis. α-defe
Externí odkaz:
https://doaj.org/article/2ee908382b004aaf9bc36a2914fbd87d
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/56b4938ab9dd4475b15900b0e49fad1a
Autor:
Valerie T Ramirez, Dayn R Godinez, Ingrid Brust-Mascher, Eric B Nonnecke, Patricia A Castillo, Mariana Barboza Gardner, Diane Tu, Jessica A Sladek, Elaine N Miller, Carlito B Lebrilla, Charles L Bevins, Melanie G Gareau, Colin Reardon
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007719 (2019)
The regulation of mucosal immune function is critical to host protection from enteric pathogens but is incompletely understood. The nervous system and the neurotransmitter acetylcholine play an integral part in host defense against enteric bacterial
Externí odkaz:
https://doaj.org/article/08cee2719d0f40789cb49ce1ac73fef5
Autor:
Ruyi Wang, Shijie Cao, Mohamed Elfatih H. Bashir, Lauren A. Hesser, Yanlin Su, Sung Min Choi Hong, Andrew Thompson, Elliot Culleen, Matthew Sabados, Nicholas P. Dylla, Evelyn Campbell, Riyue Bao, Eric B. Nonnecke, Charles L. Bevins, D. Scott Wilson, Jeffrey A. Hubbell, Cathryn R. Nagler
Publikováno v:
Nature biomedical engineering, vol 7, iss 1
The microbiome modulates host immunity and aids the maintenance of tolerance in the gut, where microbial and food-derived antigens are abundant. Yet modern dietary factors and the excessive use of antibiotics have contributed to the rising incidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ba020a68570b4cedc65bbbd059e414
https://escholarship.org/uc/item/0z07r4sm
https://escholarship.org/uc/item/0z07r4sm
Autor:
Patricia A. Castillo, Kristian K. Ullrich, Alex Bevin-Holder, Edward J. Hollox, Charles L. Bevins, Eric B. Nonnecke, Bo Lönnerdal, Faisal Almalki, Linda Odenthal-Hesse
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific reports, vol 11, iss 1
Scientific Reports
Scientific reports, vol 11, iss 1
Scientific Reports
Intelectins are a family of multimeric secreted proteins that bind microbe-specific glycans. Both genetic and functional studies have suggested that intelectins have an important role in innate immunity and are involved in the etiology of various hum