Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Charles L, Sentman"'
Autor:
Hanna Meister, Thomas Look, Patrick Roth, Steve Pascolo, Ugur Sahin, Sohyon Lee, Benjamin D. Hale, Berend Snijder, Luca Regli, Vidhya M. Ravi, Dieter Henrik Heiland, Charles L. Sentman, Michael Weller, Tobias Weiss
Publikováno v:
Clinical Cancer Research. 28:4747-4756
Purpose: Most chimeric antigen receptor (CAR) T-cell strategies against glioblastoma have demonstrated only modest therapeutic activity and are based on persistent gene modification strategies that have limited transgene capacity, long manufacturing
Autor:
Yina H. Huang, H. Robert Frost, Charles L. Sentman, Prathna Kumar, Jia Zou, Leena Abdullah, W. James Cook, Cameron M. Messier, Courtney T. Schiebout, Shannon L. Ferry, Rachel A. Brog
Chimeric-antigen receptor (CAR) T-cell therapy has shown remarkable efficacy against hematologic tumors. Yet, CAR T-cell therapy has had little success against solid tumors due to obstacles presented by the tumor microenvironment (TME) of these cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e763a90f7b7bca6c647e632a280595
https://doi.org/10.1158/2326-6066.c.6550805
https://doi.org/10.1158/2326-6066.c.6550805
Autor:
Sarah Nikiforow, Jerome Ritz, Glenn Dranoff, Robert Soiffer, Donna S. Neuberg, Richard M. Stone, Nikhil C. Munshi, Kristen Cummings, Heidi DiPietro, Ilene Galinsky, Frédéric F. Lehmann, David E. Gilham, Charles L. Sentman, Jake Reder, Adam Schmucker, Joanina K. Gicobi, Helene Trebeden-Negre, Heather Daley, Lillian Werner, Joana Murad, Susanne H. Baumeister
Adverse Events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d52b4af268577644fbdd16e762a372
https://doi.org/10.1158/2326-6066.22536640
https://doi.org/10.1158/2326-6066.22536640
Autor:
Sarah Nikiforow, Jerome Ritz, Glenn Dranoff, Robert Soiffer, Donna S. Neuberg, Richard M. Stone, Nikhil C. Munshi, Kristen Cummings, Heidi DiPietro, Ilene Galinsky, Frédéric F. Lehmann, David E. Gilham, Charles L. Sentman, Jake Reder, Adam Schmucker, Joanina K. Gicobi, Helene Trebeden-Negre, Heather Daley, Lillian Werner, Joana Murad, Susanne H. Baumeister
NKG2D ligands are widely expressed in solid and hematologic malignancies but absent or poorly expressed on healthy tissues. We conducted a phase I dose-escalation study to evaluate the safety and feasibility of a single infusion of NKG2D-chimeric ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df2480e70034b22ffe5601199e92cef9
https://doi.org/10.1158/2326-6066.c.6548194.v1
https://doi.org/10.1158/2326-6066.c.6548194.v1
Autor:
Sarah Nikiforow, Jerome Ritz, Glenn Dranoff, Robert Soiffer, Donna S. Neuberg, Richard M. Stone, Nikhil C. Munshi, Kristen Cummings, Heidi DiPietro, Ilene Galinsky, Frédéric F. Lehmann, David E. Gilham, Charles L. Sentman, Jake Reder, Adam Schmucker, Joanina K. Gicobi, Helene Trebeden-Negre, Heather Daley, Lillian Werner, Joana Murad, Susanne H. Baumeister
NKG2D-CAR T Cell Product Transduction Assessment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1242552015c56670520f4b44238469
https://doi.org/10.1158/2326-6066.22536649.v1
https://doi.org/10.1158/2326-6066.22536649.v1
Autor:
Tobias Weiss, Michael Weller, Charles L. Sentman, Dieter Henrik Heiland, Vidhya M. Ravi, Luca Regli, Berend Snijder, Benjamin D. Hale, Sohyon Lee, Ugur Sahin, Steve Pascolo, Patrick Roth, Thomas Look, Hanna Meister
Purpose:Most chimeric antigen receptor (CAR) T-cell strategies against glioblastoma have demonstrated only modest therapeutic activity and are based on persistent gene modification strategies that have limited transgene capacity, long manufacturing p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2053052cd81f21691a388b5e7a3535cb
https://doi.org/10.1158/1078-0432.c.6532824
https://doi.org/10.1158/1078-0432.c.6532824
Autor:
Tobias Weiss, Michael Weller, Charles L. Sentman, Dieter Henrik Heiland, Vidhya M. Ravi, Luca Regli, Berend Snijder, Benjamin D. Hale, Sohyon Lee, Ugur Sahin, Steve Pascolo, Patrick Roth, Thomas Look, Hanna Meister
Supplementary Figure from Multifunctional mRNA-Based CAR T Cells Display Promising Antitumor Activity Against Glioblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01416a6e310e2fc84e2b14b11f1bd7f6
https://doi.org/10.1158/1078-0432.22488870.v1
https://doi.org/10.1158/1078-0432.22488870.v1
Autor:
Rachel A. Brog, Shannon L. Ferry, Courtney T. Schiebout, Cameron M. Messier, W. James Cook, Leena Abdullah, Jia Zou, Prathna Kumar, Charles L. Sentman, H. Robert Frost, Yina H. Huang
Publikováno v:
Cancer Immunol Res
Chimeric-antigen receptor (CAR) T-cell therapy has shown remarkable efficacy against hematologic tumors. Yet, CAR T-cell therapy has had little success against solid tumors due to obstacles presented by the tumor microenvironment (TME) of these cance
revised supplementary figure legends in clean version
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742079c59e1478e4ff1dfa07891abac9
https://doi.org/10.1158/0008-5472.22417947
https://doi.org/10.1158/0008-5472.22417947
Fig S1: NKG2D expression in transduced splenocytes Fig S2: Homing of intravenous administered wtNKG2D T cells to the tumor site Fig S3: FACS Gating strategy Fig S4: Expression of NKG2DL in normal tissue Fig S5: Antigen-specific function of brain-resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2477fe436c4e469da18def04524abf08
https://doi.org/10.1158/0008-5472.22417944
https://doi.org/10.1158/0008-5472.22417944