Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Charles K. Mobley"'
Autor:
Niloofar Abolhasani Khaje, Alexander Eletsky, Sarah E. Biehn, Charles K. Mobley, Monique J. Rogals, Yoonkyoo Kim, Sushil K. Mishra, Robert J. Doerksen, Steffen Lindert, James H. Prestegard, Joshua S. Sharp
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-8 (2022)
A mass spectrometry-based method guides computational modeling for de novo protein structure prediction.
Externí odkaz:
https://doaj.org/article/c2ada858bcc842d6afa56065cc8b866e
The analysis of membrane protein topography using fast photochemical oxidation of protein (FPOP) has been reported in recent years, but still underrepresented in literature. Based on the hydroxyl radical reactivity of lipids and other amphiphiles, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11d0a42f2ddb1e6bb0d1c5cd262507e8
https://doi.org/10.1101/2020.10.19.345652
https://doi.org/10.1101/2020.10.19.345652
Autor:
Lindsey Miller, Charles K. Mobley, Evgeny Nudler, Niloofar Abolhasani Khaje, Zixuan Li, Joshua S. Sharp, Sandeep K. Misra
Fast photochemical oxidation of proteins (FPOP) may be used to characterize changes in protein structure by measuring differences in the apparent rate of peptide oxidation by hydroxyl radicals. The variability between replicates is high for some pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494e75bfb058e81d9a954353808f4b20
https://europepmc.org/articles/PMC6087495/
https://europepmc.org/articles/PMC6087495/
Publikováno v:
Biochemistry. 47:10620-10629
Dominant mutations in the tetraspan membrane protein peripheral myelin protein 22 (PMP22) are known to result in peripheral neuropathies such as Charcot-Marie-Tooth type 1A (CMT1A) disease via mechanisms that appear to be closely linked to misfolding
Autor:
Jeffrey K. Myers, Charles D. Ellis, Arina Hadziselimovic, Charles K. Mobley, Charles R. Sanders
Publikováno v:
Biochemistry. 46:11185-11195
Gene duplications, deletions, and point mutations in peripheral myelin protein 22 (PMP22) are linked to several inherited peripheral neuropathies. However, the structural and biochemical properties of this very hydrophobic putative tetraspan integral
Autor:
Charles K. Mobley, Jacob D. Moore, Stanley J. Opella, Frank D. Sönnichsen, Charles R. Sanders, Liping Ma, Richard C. Page, Timothy A. Cross, Stanley C. Howell, Sang-Won Lee, Hau B. Nguyen, Fei Philip Gao, Rose Chase, Mukesh Sharma
Publikováno v:
Journal of Structural and Functional Genomics. 7:51-64
The preparation of high quality samples is a critical challenge for the structural characterization of helical integral membrane proteins. Solving the structures of this diverse class of proteins by solution nuclear magnetic resonance spectroscopy (N
Autor:
Jason B. Benedict, Nicholas A. Straessler, Charles K. Mobley, Thomas L. Groy, M. Tyler Caudle
Publikováno v:
Inorganic Chemistry. 41:3183-3190
Heteronuclear diethylcarbamato complexes of the form ConMg6-n(Et2NCO2)12 were prepared from the isostructural homonuclear precursors Mg6(Et2NCO2)12, 1, and Co6(Et2NCO2)12, 2, via a solvothermal methodology. Two materials were selected for single-crys
Autor:
Yizhou Liu, John H. Bushweller, Fei Ji, James H. Prestegard, Huiling Chen, Victor Olman, Ying Xu, Yunpeng Zhou, Charles K. Mobley
SummaryNuclear magnetic resonance paramagnetic relaxation enhancement (PRE) measures long-range distances to isotopically labeled residues, providing useful constraints for protein structure prediction. The method usually requires labor-intensive con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd9dc28c5cafa91718c17442f17be41
https://europepmc.org/articles/PMC3099474/
https://europepmc.org/articles/PMC3099474/
Autor:
Hak Jun Kim, Arina Hadziselimovic, Charles K. Mobley, Fang Tian, Bing K. Jap, Charles R. Sanders, Andrew J. Beel, James H. Prestegard
The amyloid precursor protein (APP) is subject to alternative pathways of proteolytic processing, leading either to production of the amyloid-beta (Abeta) peptides or to non-amyloidogenic fragments. Here, we report the first structural study of C99,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c343e27efe80fe757c356130846605
https://europepmc.org/articles/PMC2572687/
https://europepmc.org/articles/PMC2572687/
Autor:
Cinzia Ambrosi, Gina E. Sosinsky, James H. Prestegard, You Zhuo, Jenny J. Yang, Juan Zou, Charles K. Mobley, Yan Y. Chen, Xue Yun Liu
Publikováno v:
Biophysical Journal. 104:406a-407a
Gap junction channels are key pathways for direct cell-cell communication that enables the intercellular diffusion of ions, second messengers, small metabolites and electrical coupling. To date, there are over 20 members of the gap junction channel f