Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Charles K. Lumpkin"'
Autor:
John L. Fowlkes, Jeffry S. Nyman, R. Clay Bunn, Gael E. Cockrell, Elizabeth C. Wahl, Mallikarjuna R. Rettiganti, Charles K. Lumpkin Jr., Kathryn M. Thrailkill
Publikováno v:
Bone Reports, Vol 1, Iss C, Pp 16-19 (2015)
In type 1 diabetes, diabetic bone disease (DBD) is characterized by decreased bone mineral density, a state of low bone turnover and an increased risk of fracture. Animal models of DBD demonstrate that acquired alterations in trabecular and cortical
Externí odkaz:
https://doaj.org/article/89a6b74e20f0427e9bcf2ebdc2dff0b3
Autor:
David L. Becton, Jaclyn VanderSchilden, Richard W. Nicholas, Kimo C. Stine, Lichu Liu, Robert C. Bunn, Charles K. Lumpkin, Larry J. Suva, Corey O. Montgomery, Robert A. Skinner, James Aronson, Elizabeth C. Wahl, Christopher J. Swearingen
Publikováno v:
Journal of Orthopaedic Research. 34:1716-1724
The majority of Osteosarcoma (OS) patients are treated with a combination of chemotherapy, resection, and limb salvage protocols. These protocols include distraction osteogenesis (DO), which is characterized by direct new bone formation. Cisplatin (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fed2942a1c04f6d50596a8011046f3f
https://doi.org/10.1002/jor.23192
https://doi.org/10.1002/jor.23192
Autor:
C. Ronald Kahn, Jeffry S. Nyman, R. Clay Bunn, Charles K. Lumpkin, Lindsey M. Morris, Kathryn M. Thrailkill, John L. Fowlkes, Elizabeth C. Wahl, Gael Cockrell
Publikováno v:
Journal of Diabetes Research, Vol 2014 (2014)
Journal of Diabetes Research
Journal of Diabetes Research
Type 1 diabetes mellitus (T1D) is associated with decreased bone mineral density, a deficit in bone structure, and subsequently an increased risk of fragility fracture. These clinical observations, paralleled by animal models of T1D, suggest that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff0bb76f02d0d3843b07df1790aa366
https://doi.org/10.1155/2014/703589
https://doi.org/10.1155/2014/703589
Autor:
David L. Becton, Lichu Liu, Larry J. Suva, James Aronson, Robert A. Skinner, Robert C. Bunn, Corey O. Montgomery, Christopher J. Swearingen, Kimo C. Stine, Elizabeth C. Wahl, Charles K. Lumpkin, Jacquelyn VanderSchilden, Richard W. Nicholas
Publikováno v:
Journal of Orthopaedic Research. 32:464-470
Osteosarcoma (OS) is the most common malignant bone tumor affecting children and adolescents. Many patients are treated with a combination of chemotherapy, resection, and limb salvage protocols. Surgical reconstructions after tumor resection include
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98d17cb0f4ccbe239ebe261e06b01f2c
https://doi.org/10.1002/jor.22527
https://doi.org/10.1002/jor.22527
Autor:
Charles K. Lumpkin, R. Clay Bunn, John L. Fowlkes, Lindsey M. Morris, Elizabeth C. Wahl, Gael Cockrell, Lichu Liu, Chan-Hee Jo, Jeffry S. Nyman, Kathryn M. Thrailkill
Publikováno v:
Bone. 57:36-40
Objective Using a streptozotocin (STZ)-induced mouse model of type 1 diabetes (T1D), we have previously demonstrated that long-term diabetes inhibits regenerative bone formation during tibial distraction osteogenesis (DO) and perturbs skeletal integr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f84a58a78cb9643a1d71b14cf3c3aa
https://doi.org/10.1016/j.bone.2013.07.017
https://doi.org/10.1016/j.bone.2013.07.017
Autor:
Kathryn M. Thrailkill, Katherine L. Thompson, R. Clay Bunn, Sasidhar Uppuganti, Jeffry S. Nyman, Charles K. Lumpkin, John L. Fowlkes, Evangelia Kalaitzoglou
Publikováno v:
Bone. 94
Skeletal co-morbidities in type 1 diabetes include an increased risk for fracture and delayed fracture healing, which are intertwined with disease duration and the presence of other diabetic complications. As such, chronic hyperglycemia is undoubtedl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d140e31e503fa096afd28f6b6f5103ef
https://pubmed.ncbi.nlm.nih.gov/27989651
https://pubmed.ncbi.nlm.nih.gov/27989651
Distraction osteogenesis in TNF receptor 1 deficient mice is protected from chronic ethanol exposure
Autor:
Lichu Liu, Elizabeth C. Wahl, Martin J. J. Ronis, Charles K. Lumpkin, Robert A. Skinner, James Aronson
Publikováno v:
Alcohol. 46:133-138
Distraction osteogenesis (DO) is an orthopedic protocol, which induces direct new bone formation as a result of the stimulating effects of mechanical distraction. Chronic ethanol exposure has been demonstrated to inhibit bone formation in rodent mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547d10c8b94e229b8bd120f542034bfb
https://doi.org/10.1016/j.alcohol.2011.08.007
https://doi.org/10.1016/j.alcohol.2011.08.007
Autor:
Charles K. Lumpkin, Kathryn M. Thrailkill, Chan-Hee Jo, Erik G. Herbert, R. Clay Bunn, Jeffry S. Nyman, Gael Cockrell, Elizabeth C. Wahl, Jesse L. Even, John L. Fowlkes, Matthew R. Murry
Publikováno v:
Bone. 48:733-740
Type 1 diabetes (T1DM) increases the likelihood of a fracture. Despite serious complications in the healing of fractures among those with diabetes, the underlying causes are not delineated for the effect of diabetes on the fracture resistance of bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a838d314ffc52c1621c5a8493c209ea5
https://doi.org/10.1016/j.bone.2010.12.016
https://doi.org/10.1016/j.bone.2010.12.016
Autor:
Robert C. Bunn, Charles K. Lumpkin, Lichu Liu, Robert A. Skinner, James Aronson, Elizabeth C. Wahl, Gael Cockrell, Kathryn M. Thrailkill, John L. Fowlkes, Mike J. Miller, Martin J. J. Ronis
Publikováno v:
Bone. 46:410-417
Distraction osteogenesis (DO) is a process which induces direct new bone formation as a result of mechanical distraction. Tumor necrosis factor-alpha (TNF) is a cytokine that can modulate osteoblastogenesis. The direct effects of TNF on direct bone f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1a4590a42100a8813c12e006241e1d
https://doi.org/10.1016/j.bone.2009.09.011
https://doi.org/10.1016/j.bone.2009.09.011
Autor:
Chan-Hee Jo, Kathryn M. Thrailkill, Robert C. Bunn, Cynthia S. Moreau, John L. Fowlkes, Alba E. Morales-Pozzo, Charles K. Lumpkin, Gael Cockrell
Publikováno v:
Endocrine. 37:336-343
Neutrophil gelatinase-associated lipocalin (NGAL), a biomarker of renal injury, can bind matrix metalloproteinase-9 (MMP-9) and inhibit its degradation, thereby sustaining MMP-9 proteolytic activity. MMP-9 is produced by renal podocytes, and podocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98f11d75041c3af929c2180971d7339
https://doi.org/10.1007/s12020-010-9308-6
https://doi.org/10.1007/s12020-010-9308-6