Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Charles K. Li"'
1
Overexpression of MHC Class I Heavy Chain Protein in Young Skeletal Muscle Leads to Severe Myositis
Autor: Sonia Shah, Paul Knopp, Bhanu P. Singh, Halima Moncrieffe, Charles K. Li, Bin Gao, Lucy R. Wedderburn, Kanneboyina Nagaraju, Hemlata Varsani
Publikováno v: The American Journal of Pathology. 175:1030-1040
Folding and transport of proteins, such as major histocompatibility complex (MHC) class I, through the endoplasmic reticulum (ER) is tightly regulated in all cells, including muscle tissue, where the specialized ER sarcoplasmic reticulum is also crit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::271adb72d4d664d0d5c036f5918d0729
https://doi.org/10.2353/ajpath.2009.090196
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2
Systemic lupus erythematosus
Autor: Charles K. Li, David A. Isenberg
Publikováno v: Medicine. 34:445-452
Systemic lupus erythematosus (SLE) is a diverse autoimmune rheumatic disease principally affecting women during childbearing years. The female-to-male ratio is around 9:1. Although virtually all patients have skin and joint disease between 30 and 50%
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cf894c9c8d667ec2000d8a462c5dd126
https://doi.org/10.1053/j.mpmed.2006.09.002
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3
Paediatric idiopathic inflammatory muscle disease
Autor: Charles K. Li, Lucy R. Wedderburn
Publikováno v: Best Practice & Research Clinical Rheumatology. 18:345-358
The paediatric idiopathic inflammatory myopathies (IIMs) are a group of rare but serious systemic autoimmune conditions of childhood. The most common of the paediatric IIMs is juvenile dermatomyositis (JDM), while polymyositis and inclusion body myos
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85711a9cdba8905b4888b0b46ada31a
https://doi.org/10.1016/j.berh.2004.01.003
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4
Quantification of normal range of inflammatory changes in morphologically normal pediatric muscle
Autor: Charles K. Li, Lucy R. Wedderburn, Janice L. Holton, Hemlata Varsani, Katy Newton, Brian Harding
Publikováno v: Muscle & Nerve. 37:259-261
The aim of this study was to define normal ranges of histological features in pediatric muscle in comparison with muscle demonstrating inflammatory changes. Sixteen pediatric muscle biopsy samples, considered normal by standard histology, were analyz
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::33ff1a8c6a44aae6a6c2346e22ecf604
https://doi.org/10.1002/mus.20898
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6
Juvenile dermatomyositis: new insights and new treatment strategies
Autor: Lucy R. Wedderburn, Charles K. Li, Neil Martin
Juvenile dermatomyositis (JDM) is a rare but complex and potentially life-threatening autoimmune disease of childhood, primarily affecting proximal muscles and skin. Although the cause of JDM remains unknown it is clear that genetic and environmental
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68f8f80d23a9e004e9eed717d47a3d6
https://europepmc.org/articles/PMC3383527/
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7
Upregulation of MHC class I in transgenic mice results in reduced force-generating capacity in slow-twitch muscle
Autor: Kanneboyina Nagaraju, Shi-Jin Zhang, Håkan Westerblad, Cecilia Grundtman, Charles K. Li, Abram Katz, Lucy R. Wedderburn, Johanna T. Lanner, S Salomonsson, Ingrid E. Lundberg
Publikováno v: Musclenerve. 39(5)
Expression of major histocompatibility complex (MHC) class I in skeletal muscle fibers is an early and consistent finding in inflammatory myopathies. To test if MHC class I has a primary role in muscle impairment, we used transgenic mice with inducib
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083f169be1a6e2f107f7ec91b52c3399
https://pubmed.ncbi.nlm.nih.gov/19229963
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8
Quantification of normal range of inflammatory changes in morphologically normal pediatric muscle
Autor: Hemlata, Varsani, Katy R, Newton, Charles K, Li, Brian, Harding, Janice L, Holton, Lucy R, Wedderburn
Publikováno v: Musclenerve. 37(2)
The aim of this study was to define normal ranges of histological features in pediatric muscle in comparison with muscle demonstrating inflammatory changes. Sixteen pediatric muscle biopsy samples, considered normal by standard histology, were analyz
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::144dbac47d1e3aaa42a8954348be4f4f
https://pubmed.ncbi.nlm.nih.gov/17847070
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10
A novel form of immune inflammatory myopathy associated with antibodies to γ/δ sarcoglycan
Autor: Jill Moss, Russell J.M. Lane, Poonam Singh, Chiara Marini-Bettolo, Federico Roncaroli, Peter Charles, Charles K. Li
Publikováno v: Annals of the Rheumatic Diseases. 71:A47.2-A48
Immune mediated inflammatory myopathies are a heterogeneous group of acquired diseases characterised by inflammation of skeletal muscle. In recent years, this group of conditions has become better characterised by the detection of autoantibodies to a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b100098816821f2e051960087bc1de6
https://doi.org/10.1136/annrheumdis-2011-201235.13
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