Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Charles K, Job"'
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 78:518-521
It is generally held that dissemination of Mycobacterium leprae is from nasal mucosa and not through the skin of infected patients. In this study, we evaluated M. leprae in the unbroken skin and nasal secretions of multibacillary (MB) leprosy patient
Autor:
Bikash Ranjan Kar, Charles K. Job
Publikováno v:
Leprosy Review. 76:258-262
A 22-year-old male polar lepromatous leprosy patient who became Mitsuda positive after 36 months of multidrug therapy (MDT) is reported. Lepromatous leprosy (LL) is a state of specific immunosuppression and is invariably irreversible. The finding of
Publikováno v:
Leprosy Review. 75:282-288
Serum lactoferrin level, using competitive enzyme linked immunosorbent assay (ELISA) method, was estimated in 298 leprosy patients admitted into the hospital and attending the out-patient department of the Schieffelin Leprosy Research and Training Ce
Publikováno v:
Indian Journal of Ophthalmology
Leprosy is a chronic granulomatous disease caused by Mycobacterium leprae , clinically present either as tuberculoid, borderline or lepromatous type. Erythema nodosum leprosum (ENL) is an acute humoral response in the chronic course of lepromatous le
Autor:
Charles K. Job, Posettihalli R. Satish, Lavanya M. Suneetha, Sujai Suneetha, Aiylam S. Balasubramanian, Ravi J. Korula
Publikováno v:
Neurochemical Research. 23:907-911
Mycobacterium leprae, the causative agent of leprosy, specifically invades and destroys the peripheral nerve, which results in the main clinical manifestation of the disease. Little is known about the bacteria-nerve protein interaction. We show in th
Autor:
Charles K. Job, Robert E. Neimes, Tomasz F. Mroczkowski, Pablo I. Almodovar, Wojciech A. Krotoski, Robert C. Hastings, Thomas H. Rea, Martti K. Kahkonen, Bruce C. Clements
Publikováno v:
The American Journal of the Medical Sciences. 305:18-24
Hansen's disease, or leprosy, although a relatively uncommon disease in the United States, continues to be important because of its implications--physical, psychological, and social--for the patient. Prognosis and treatment of the disease are based l
Autor:
Paolo Fiallo, Thomas P. Gillis, Diana L. Williams, Charles K. Job, Shinzo Izumi, Robert H. Gelber, Carlotta Hill
Publikováno v:
Molecular and Cellular Probes. 6:401-410
An improved protocol for PCR analysis of Mycobacterium leprae-infected tissues, based on enzymatic lysis, has been developed and used to demonstrate the feasibility of using PCR for detecting M. leprae in routine skin biopsies taken from leprosy pati
Publikováno v:
The American journal of tropical medicine and hygiene. 78(3)
It is generally held that dissemination of Mycobacterium leprae is from nasal mucosa and not through the skin of infected patients. In this study, we evaluated M. leprae in the unbroken skin and nasal secretions of multibacillary (MB) leprosy patient
Publikováno v:
Journal of the American Academy of Dermatology. 23:236-241
Skin biopsy specimens from two lepromatous leprosy patients with dark brown pigmentation who were receiving long-term clofazimine therapy were studied. Ceroid-lipofuscin pigment was demonstrated inside macrophages that contained numerous phagolysosom
Publikováno v:
Indian journal of dermatology, venereology and leprology. 71(4)
A 49-year-old man with lepromatous leprosy treated with dapsone monotherapy for 12 years (1967 to 1979) reported in the hospital in 2003, with relapsed disease. A slit skin smear showed a bacteriological index of 4+. Biopsies from skin lesions before