Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Charles J. Tucker"'
Autor:
Xingyao Li, Regan B. Kirkpatrick, Xiaodong Wang, Charles J. Tucker, Anuj Shukla, Henning J. Jessen, Huanchen Wang, Stephen B. Shears, Chunfang Gu
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114316- (2024)
Summary: Phosphate (Pi) serves countless metabolic pathways and is involved in macromolecule synthesis, energy storage, cellular signaling, and bone maintenance. Herein, we describe the coordination of Pi uptake and efflux pathways to maintain mammal
Externí odkaz:
https://doaj.org/article/f3b6e793e06f4a21a4aaa698b4a545cf
Autor:
Zaniya A. Mark, Linda Yu, Lysandra Castro, Xiaohua Gao, Noelle R. Rodriguez, Deloris Sutton, Erica Scappini, Charles J. Tucker, Rob Wine, Yitang Yan, Evangeline Motley, Darlene Dixon
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4902 (2024)
High-risk human papillomavirus (HR-HPV; HPV-16) and cigarette smoking are associated with cervical cancer (CC); however, the underlying mechanism(s) remain unclear. Additionally, the carcinogenic components of tobacco have been found in the cervical
Externí odkaz:
https://doaj.org/article/f0e026734b7c443983bb02a139b3b7a6
Autor:
Carol S. Trempus, Brian N. Papas, Maria I. Sifre, Carl D. Bortner, Erica Scappini, Charles J. Tucker, Xin Xu, Katina L. Johnson, Leesa J. Deterding, Jason G. Williams, Dylan J. Johnson, Jian-Liang Li, Deloris Sutton, Charan Ganta, Debabrata Mahapatra, Muhammad Arif, Abhishek Basu, Lenny Pommerolle, Resat Cinar, Anne K. Perl, Stavros Garantziotis
Publikováno v:
JCI Insight, Vol 8, Iss 22 (2023)
Aberrant fibroblast function plays a key role in the pathogenesis of idiopathic pulmonary fibrosis, a devastating disease of unrelenting extracellular matrix deposition in response to lung injury. Platelet-derived growth factor α–positive (Pdgfra+
Externí odkaz:
https://doaj.org/article/995c258facf24a35b92fa8b7165434cb
Autor:
Motoki Takaku, Sara A. Grimm, John D. Roberts, Kaliopi Chrysovergis, Brian D. Bennett, Page Myers, Lalith Perera, Charles J. Tucker, Charles M. Perou, Paul A. Wade
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
In breast cancer GATA3 is known to be frequently mutated, but the function of these mutations is unclear. Here, the authors utilise CRISPR-Cas9 to model frame-shift mutations in zinc finger 2 of GATA3, highlighting that GATA3 mutation can have gain-
Externí odkaz:
https://doaj.org/article/5f5be941e8644deb8f837c3cb577731d
Publikováno v:
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-14 (2017)
Abstract Background Multi-walled carbon nanotubes (MWCNTs) are engineered nanomaterials used for a variety of industrial and consumer products. Their high tensile strength, hydrophobicity, and semi-conductive properties have enabled many novel applic
Externí odkaz:
https://doaj.org/article/9a0fa15c5ecd410fbbd2e9cc747eac3b
Publikováno v:
Frontiers in Neuroanatomy, Vol 12 (2019)
Visualization and quantification of fluorescently labeled axonal fibers are widely employed in studies of neuronal connectivity in the brain. However, accurate analysis of axon density is often confounded by autofluorescence and other fluorescent art
Externí odkaz:
https://doaj.org/article/c5b5ba7104c3449ca2ed4fbb2be86d5a
Autor:
Wei Qu, Yitang Yan, Kevin Gerrish, Erica Scappini, Charles J. Tucker, Darlene Dixon, B. Alex Merrick
Publikováno v:
Toxicology in Vitro. 89:105577
Autor:
Yu-Ping Lin, Erica Scappini, Carlos Landaverde, Frederick Parekh-Glitsch, Charles J. Tucker, Gary R. Mirams, Anant B. Parekh
Publikováno v:
Mol Cell Biol
A-kinase anchoring protein 79 (AKAP79) is a human scaffolding protein that organizes Ca(2+)/calmodulin-dependent protein phosphatase calcineurin, calmodulin, cAMP-dependent protein kinase, protein kinase C, and the transcription factor nuclear factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79717e80995f14eb7536789084679dc
https://europepmc.org/articles/PMC9670898/
https://europepmc.org/articles/PMC9670898/
Publikováno v:
Function. 3
In many cell types, the rise in cytosolic Ca2+ due to opening of Ca2+ release-activated Ca2+ (CRAC) channels drives a plethora of responses, including secretion, motility, energy production, and gene expression. The amplitude and time course of the c
Autor:
Darlene Dixon, Yitang Yan, Kevin Gerrish, Rick Fannin, Michael J. Dykstra, Jingli Liu, Erica L. Scappini, Charles J. Tucker, Arianna Lawrence
Publikováno v:
The FASEB Journal
The heavy metal Cadmium (Cd), a widespread environmental contaminant, poses serious hazards to human health and is considered a metallohormone and carcinogen. In women with uterine fibroids, there is a significant association between blood Cd levels