Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Charles J. R. Hedgecock"'
Publikováno v:
Tetrahedron: Asymmetry. 6:2507-2510
Synthesis of an enantiomerically pure intermediate to (+)-thienamycin is presented: the pivotal reaction in this sequence is the highly diastereoselective Michael addition of a differentially protected lithium amide.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da63365a8aeae8a25d53b03f5acd98d3
https://doi.org/10.1016/0957-4166(95)00327-l
https://doi.org/10.1016/0957-4166(95)00327-l
Publikováno v:
Proteins: Structure, Function, and Genetics. 17:11-19
Interleukin-4 is a member of the cytokine family, a group of related messenger proteins which collectively help to moderate and control the immune response. It is believed that the folding topology of the β-sheets of the interleukin-4 receptor (IL4R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc7598bc3d0e2843afea9a413f7b89f
https://doi.org/10.1002/prot.340170105
https://doi.org/10.1002/prot.340170105
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ece9653013ae6c49114beb19b2b6ab05
https://doi.org/10.1002/chin.199220295
https://doi.org/10.1002/chin.199220295
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83183e66dde77567a4846c70408e9e6a
https://doi.org/10.1002/chin.199220044
https://doi.org/10.1002/chin.199220044
Publikováno v:
ChemInform. 26
Conjugate addition of lithium N -allyl- N - α -methylbenzylamide to chiral α,β-unsaturated esters is subject to double stereodifferentiation, the mismatched pair reaction allowing access to an intermediate for 1β-methylcarbapenem synthesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32104c2f96e880261afbcb27f20c81e6
https://doi.org/10.1002/chin.199536283
https://doi.org/10.1002/chin.199536283
Publikováno v:
ChemInform. 27
Synthesis of an enantiomerically pure intermediate to (+)-thienamycin is presented: the pivotal reaction in this sequence is the highly diastereoselective Michael addition of a differentially protected lithium amide.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df1262572c9d78413fe47771e1389ac1
https://doi.org/10.1002/chin.199611301
https://doi.org/10.1002/chin.199611301
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4fc44e2581121a2250ac2e20345834b
https://doi.org/10.1002/chin.199649221
https://doi.org/10.1002/chin.199649221
Publikováno v:
European journal of immunology. 27(11)
The signaling function of the T cell antigen receptor (TCR) is mediated via CD3 polypeptides, the cytoplasmic sequences of which bear conserved immunoreceptor tyrosine-based activation motifs (ITAM). ITAM are defined by two YxxL/I sequences separated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::143e9875a01dd5972469ad226d284b56
https://pubmed.ncbi.nlm.nih.gov/9394831
https://pubmed.ncbi.nlm.nih.gov/9394831
Autor:
James F. Costello, Stephen G. Davies, Stephen C. Case-Green, Vanessa M. Humphreys, Jeremy C. Primes, Charles J. R. Hedgecock, Michael R. Metzler, Nicholas Heaton
Publikováno v:
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1. (8)
The chiral iron acetyl complexes [Fe(CO)(η5-C 5H5)(L)COCH3] [L = PPh3, P(p-tolyl)3] have been kinetically resolved via aldol reactions involving their derived lithium enolates and camphor in the presence of lithium chloride. With (1R)-(+)-camphor th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64ad0adf4ccb574cf1b03b89c0f20e0
http://ora.ox.ac.uk/objects/uuid:732a80c4-5205-4382-9a1f-7bc297dba241
http://ora.ox.ac.uk/objects/uuid:732a80c4-5205-4382-9a1f-7bc297dba241