Výsledky vyhledávání - "Charles J. Haney"

Regulation of Sar1 NH2 terminus by GTP binding and hydrolysis promotes membrane deformation to control COPII vesicle fission

Autor: Sergei I. Bannykh, Gavin Gabreski, Anna Bielli, Meir Aridor, Charles J. Haney, Simon C. Watkins

Publikováno v: The Journal of Cell Biology

The mechanisms by which the coat complex II (COPII) coat mediates membrane deformation and vesicle fission are unknown. Sar1 is a structural component of the membrane-binding inner layer of COPII (Bi, X., R.A. Corpina, and J. Goldberg. 2002. Nature.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f0bc27b2bdcf5a438e2bdb8aa226f1
https://doi.org/10.1083/jcb.200509095

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Activation of phospholipase D by the small GTPase Sar1p is required to support COPII assembly and ER export

Autor: Guillermo Romero, Simon C. Watkins, Sean Alber, Anna Blumental-Perry, Anna Bielli, Meir Aridor, Kuntala Shome, Charles J. Haney, Purnima Pathre

Publikováno v: The EMBO journal. 22(16)

The small GTPase Sar1p controls the assembly of the cytosolic COPII coat that mediates export from the endoplasmic reticulum (ER). Here we demonstrate that phospholipase D (PLD) activation is required to support COPII-mediated ER export. PLD activity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88bee90fab2b892fe5f1a67cc52ae2a9
https://pubmed.ncbi.nlm.nih.gov/12912905

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