Nephron mass determines the excretion rate of urinary extracellular vesicles

Autor: Charles J. Blijdorp, Thomas A. Hartjes, Kuang‐Yu Wei, Martijn H. vanHeugten, Dominique M. Bovée, Ricardo P.J. Budde, Jacqueline van deWetering, Joost G.J. Hoenderop, Martin E. vanRoyen, Robert Zietse, David Severs, Ewout J. Hoorn

Publikováno v: Journal of Extracellular Vesicles, Vol 11, Iss 1, Pp n/a-n/a (2022)

Abstract Urinary extracellular vesicles (uEVs) are emerging as non‐invasive biomarkers for various kidney diseases, but it is unknown how differences in nephron mass impact uEV excretion. To address this, uEV excretion was measured before and after

Externí odkaz: https://doaj.org/article/3d7c771258b24986914dd56724c415cf

Extracellular Vesicles in Kidney Diseases: Moving Forward

Autor: Uta Erdbrügger, Ewout J. Hoorn, Thu H. Le, Charles J. Blijdorp, Dylan Burger

Publikováno v: Kidney360. 4:245-257

Extracellular vesicles (EVs) are evolving as novel cell mediators, biomarkers, and therapeutic targets in kidney health and disease. They are naturally derived from cells both within and outside the kidney and carry cargo which mirrors the state of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d751b88dddd8f8a23948f2b44e431e41
https://doi.org/10.34067/kid.0001892022

Extracellular Vesicles as Novel Players in Kidney Disease

Autor: Charles J. Blijdorp, Dylan Burger, Alicia Llorente, Elena S. Martens-Uzunova, Uta Erdbrügger

Publikováno v: Journal of the American Society of Nephrology
Journal of the American Society of Nephrology, 33(3), 467-471. American Society of Nephrology
J Am Soc Nephrol

“Urine can provide us day by day, month by month, and year by year with a serial story of the major events within the kidney.” Dr. Thomas Addis, pioneer in renal physiology, came to this conclusion in 1948. The discovery of urinary extracellular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12be0ced3aceb3929e660ded059402c
https://hdl.handle.net/11250/3039312

Urinary Extracellular Vesicles in Urology: Current Successes and Challenges Ahead

Autor: Uta Erdbrügger, Charles J. Blijdorp, Elena S. Martens-Uzunova, Dylan Burger, Alicia Llorente

Publikováno v: European Urology, 81(1), 127-128. Elsevier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755d89db4aa3d639920c7aae917df7cd
https://doi.org/10.1016/j.eururo.2021.09.025

Urinary Extracellular Vesicles: A Position Paper by the Urine Task Force of the International Society for Extracellular Vesicles

Autor: Juan M. Falcón-Pérez, Dylan Burger, Aled Clayton, Lei Zheng, Uta Erdbrügger, Kerstin Junker, Luca Musante, Ewout J. Hoorn, I.V. Bijnsdorp, Kenneth W. Witwer, Harry Holthöfer, James W. Dear, Erik H. Koritzinsky, Benedetta Bussolati, Jason P. Webber, Elena S. Martens-Uzunova, Charles J. Blijdorp, Inge Mertens, Alicia Llorente, James M. Luther, Peter S.T. Yuen, Catherine Sánchez, Janne Leivo, Andrew F. Hill, Guido Jenster, Eline Oeyen, Visith Thongboonkerd, Cristina Grange, Metka Lenassi, Maija Puhka, Carolina Soekmadji, Volkert van Steijn, Francesc E. Borràs, James Brian Byrd, Martin E. van Royen, Gerald W. Verhaegh, Mark A. Knepper, John Klein, Connie R. Jimenez

Publikováno v: Erdbrügger, U, Blijdorp, C J, Bijnsdorp, I V, Borràs, F E, Burger, D, Bussolati, B, Byrd, J B, Clayton, A, Dear, J W, Falcón-Pérez, J M, Grange, C, Hill, A F, Holthöfer, H, Hoorn, E J, Jenster, G, Jimenez, C R, Junker, K, Klein, J, Knepper, M A, Koritzinsky, E H, Luther, J M, Lenassi, M, Leivo, J, Mertens, I, Musante, L, Oeyen, E, Puhka, M, van Royen, M E, Sánchez, C, Soekmadji, C, Thongboonkerd, V, van Steijn, V, Verhaegh, G, Webber, J P, Witwer, K W, Yuen, P S T, Lei, Z, Llorente, A & Martens-Uzunova, E S 2021, ' Urinary Extracellular Vesicles: A Position Paper by the Urine Task Force of the International Society for Extracellular Vesicles ', Journal of Extracellular Vesicles . https://doi.org/10.1002/jev2.12093
Journal of Extracellular Vesicles
e12093
Journal of Extracellular Vesicles, Vol 10, Iss 7, Pp n/a-n/a (2021)
Erdbrügger, U, Blijdorp, C J, Bijnsdorp, I V, Borràs, F E, Burger, D, Bussolati, B, Byrd, J B, Clayton, A, Dear, J W, Falcón-Pérez, J M, Grange, C, Hill, A F, Holthöfer, H, Hoorn, E J, Jenster, G, Jimenez, C R, Junker, K, Klein, J, Knepper, M A, Koritzinsky, E H, Luther, J M, Lenassi, M, Leivo, J, Mertens, I, Musante, L, Oeyen, E, Puhka, M, van Royen, M E, Sánchez, C, Soekmadji, C, Thongboonkerd, V, van Steijn, V, Verhaegh, G, Webber, J P, Witwer, K, Yuen, P S T, Zheng, L, Llorente, A & Martens-Uzunova, E S 2021, ' Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles ', Journal of Extracellular Vesicles, vol. 10, no. 7, e12093 . https://doi.org/10.1002/jev2.12093
Journal of Extracellular Vesicles, 10(7):e12093. Taylor & Francis Ltd
Journal of Extracellular Vesicles, 10, 7
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Journal of Extracellular Vesicles, 10(7):e12093. Taylor and Francis Ltd.
Journal of Extracellular Vesicles, 10
Journal of Extracellular Vesicles, 10(7)

Urine is commonly used for clinical diagnosis and biomedical research. The discovery of extracellular vesicles (EV) in urine opened a new fast-growing scientific field. In the last decade urinary extracellular vesicles (uEVs) were shown to mirror mol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1aef6124e15e20c47bd672dab407d67
https://www.pure.ed.ac.uk/ws/files/207983692/uEV_position_paper_Accepted_Version.docx