Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Charles J Lowenstein"'
Autor:
Emma G Bouck, Marios Arvanitis, William O Osburn, Yaqiu Sang, Paula Reventun, Homa K Ahmadzia, Nicholas L Smith, Charles J Lowenstein, Alisa S Wolberg
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284333 (2023)
BackgroundOral contraceptive (OC) use increases venous thromboembolism risk 2-5-fold. Procoagulant changes can be detected in plasma from OC users even without thrombosis, but cellular mechanisms that provoke thrombosis have not been identified. Endo
Externí odkaz:
https://doaj.org/article/8a4b7500898a4dea84b13d6da7d48daf
Autor:
William O Osburn, Kimberly Smith, Lisa Yanek, Nuria Amat-Alcaron, David R Thiemann, Andrea L Cox, Thorsten M Leucker, Charles J Lowenstein
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0268296 (2022)
Severe coronavirus disease-19 (COVID-19) is characterized by vascular inflammation and thrombosis. We and others have proposed that the inflammatory response to coronavirus infection activates endothelial cells, leading to endothelial release of pro-
Externí odkaz:
https://doaj.org/article/b760add11e2f42b5bf3764b890c83fd7
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147167 (2016)
Externí odkaz:
https://doaj.org/article/f62243a92f2c40c5b940144d90f73d62
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0118737 (2015)
Endothelial exocytosis regulates vascular thrombosis and inflammation. The trafficking and release of endothelial vesicles is mediated by SNARE (Soluble NSF Attachment protein REceptors) molecules, but the exact identity of endothelial SNAREs has bee
Externí odkaz:
https://doaj.org/article/d6bf81f75b5049d980a1bcfea09f06cf
Autor:
Scott J Cameron, Craig N Morrell, Clare Bao, AnneMarie F Swaim, Annabelle Rodriguez, Charles J Lowenstein
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144372 (2015)
High density lipoprotein has anti-inflammatory effects in addition to mediating reverse cholesterol transport. While many of the chronic anti-inflammatory effects of high density lipoprotein (HDL) are attributed to changes in cell adhesion molecules,
Externí odkaz:
https://doaj.org/article/3649550db0bd4a0ea3f44214632835ab
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20291 (2011)
MicroRNAs (MiRNAs) are short, non-coding RNA that regulate a variety of cellular functions by suppressing target protein expression. We hypothesized that a set of microRNA regulate tumor responses to hypoxia by inhibiting components of the hypoxia si
Externí odkaz:
https://doaj.org/article/ffe327b4d41a4c5c8c08f23854e56cb4
Autor:
Pablo Toledano-Sanz, Paula Reventun, Maria Viskadourou, William O. Osburn, Nunzio Alcharani, Charles J. Lowenstein, Marios Arvanitis
Publikováno v:
Blood Advances. 7:2047-2052
Autor:
Pearl Quijada, Shuin Park, Peng Zhao, Kamal S.S. Kolluri, David Wong, Kevin D. Shih, Kai Fang, Arash Pezhouman, Lingjun Wang, Ali Daraei, Matthew D. Tran, Elle M. Rathbun, Kimberly N. Burgos Villar, Maria L. Garcia-Hernandez, Thanh T.D. Pham, Charles J. Lowenstein, M. Luisa Iruela-Arispe, S. Thomas Carmichael, Eric M. Small, Reza Ardehali
Publikováno v:
The Journal of clinical investigation, vol 133, iss 10
Despite the prevalence of pericytes in the microvasculature of the heart, their role during ischemia-induced remodeling remains unclear. We used multiple lineage-tracing mouse models and found that pericytes migrated to the injury site and expressed
Autor:
Jeffrey C. Trost, Jon R. Resar, Charles J. Lowenstein, Erin D. Michos, Rani K. Hasan, Eric P. Nolley, Allison G. Hays, Andreas S. Barth, Matthew J. Czarny, Lori J. Sokoll, Thomas S. Metkus, David R. Thiemann, Wendy S. Post
Publikováno v:
Circulation
Supplemental Digital Content is available in the text.
Background: Knowledge gaps remain in the epidemiology and clinical implications of myocardial injury in coronavirus disease 2019 (COVID-19). We aimed to determine the prevalence and outcomes
Background: Knowledge gaps remain in the epidemiology and clinical implications of myocardial injury in coronavirus disease 2019 (COVID-19). We aimed to determine the prevalence and outcomes
Autor:
Mahsima Shabani, Diptavo Dutta, Wendy Post, Charles J Lowenstein, Bharath Ambale Venkatesh, Nilanjan Chatterjee, Matthew Budoff, Stephen S Rich, Jerome I Rotter, Dan E Arking, Joao Lima
Publikováno v:
Circulation. 144
Introduction: Even though various risk estimators are widely used to predict atherosclerosis from subclinical levels to hard CHD, there is a remarkable proportion of low-risk individuals with inordinately high coronary artery calcification (CAC) or w