Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Charles J Bieberich"'
Autor:
Mindy K. Graham, Rulin Wang, Roshan Chikarmane, Bulouere Abel, Ajay Vaghasia, Anuj Gupta, Qizhi Zheng, Jessica Hicks, Polina Sysa-Shah, Xin Pan, Nicole Castagna, Jianyong Liu, Jennifer Meyers, Alyza Skaist, Yan Zhang, Michael Rubenstein, Kornel Schuebel, Brian W. Simons, Charles J. Bieberich, William G. Nelson, Shawn E. Lupold, Theodore L. DeWeese, Angelo M. De Marzo, Srinivasan Yegnasubramanian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract How prostate cancer cells and their precursors mediate changes in the tumor microenvironment (TME) to drive prostate cancer progression is unclear, in part due to the inability to longitudinally study the disease evolution in human tissues.
Externí odkaz:
https://doaj.org/article/e570ed028e564316b359132fbf5d96e9
Autor:
Tsuyoshi Iwata, Denise Schultz, Jessica Hicks, Gretchen K Hubbard, Laura N Mutton, Tamara L Lotan, Carlise Bethel, Matthew T Lotz, Srinivasan Yegnasubramanian, William G Nelson, Chi V Dang, MengMeng Xu, Uzoma Anele, Cheryl M Koh, Charles J Bieberich, Angelo M De Marzo
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9427 (2010)
Lo-MYC and Hi-MYC mice develop prostatic intraepithelial neoplasia (PIN) and prostatic adenocarcinoma as a result of MYC overexpression in the mouse prostate. However, prior studies have not determined precisely when, and in which cell types, MYC is
Externí odkaz:
https://doaj.org/article/59ed23f304684ff8b997f9f9164b889e
Publikováno v:
Medical Sciences, Vol 10, Iss 2, p 31 (2022)
Polyamine biosynthesis is frequently dysregulated in cancers, and enhanced flux increases intracellular polyamines necessary for promoting cell growth, proliferation, and function. Polyamine depletion strategies demonstrate efficacy in reducing tumor
Externí odkaz:
https://doaj.org/article/cd6982c775e74953aaa7b6580f863085
Autor:
Taduru L. Sreenath, Shiela S. Macalindong, Natallia Mikhalkevich, Shashwat Sharad, Ahmed Mohamed, Denise Young, Talaibek Borbiev, Charles Xavier, Rishita Gupta, Muhammad Jamal, Kevin Babcock, Shyh-Han Tan, Marja T. Nevalainen, Albert Dobi, Gyorgy Petrovics, Isabell A. Sesterhenn, Inger L. Rosner, Charles J. Bieberich, Peter Nelson, Valeri Vasioukhin, Shiv Srivastava
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Mechanistic studies of deregulated ERG in prostate cancer and other cancers continue to enhance its role in cancer biology and its utility as a biomarker and therapeutic target. Here, we show that ERG, through its physical interaction with a
Externí odkaz:
https://doaj.org/article/d5ee1bf16e654954959d31a94f341a87
Publikováno v:
Fluids, Vol 6, Iss 8, p 272 (2021)
This work discusses in vivo experiments that were performed to evaluate whether local or whole-body heating to 40 °C reduced interstitial fluid pressures (IFPs) and enhanced nanoparticle delivery to subcutaneous PC3 human prostate cancer xenograft t
Externí odkaz:
https://doaj.org/article/b6f7414d436244ca923078944f7f595e
Autor:
Charles J. Bieberich, Angelo M. De Marzo, Srinivasan Yegnasubramanian, Peter S. Nelson, Michael S. Moubarek, Ibrahim Kulac, Lucas A. Horn, Daniella Bianchi-Frias, Jessica L. Hicks, Ryan P. McMullin, May Khalili, Laura N. Mutton, Gretchen K. Hubbard
Genetic instability, a hallmark feature of human cancers including prostatic adenocarcinomas, is considered a driver of metastasis. Somatic copy number alterations (CNA) are found in most aggressive primary human prostate cancers, and the overall num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5f4962b0ffc42ccd0b4f93315e5992
https://doi.org/10.1158/0008-5472.c.6507936.v1
https://doi.org/10.1158/0008-5472.c.6507936.v1
Autor:
Angelo M. De Marzo, Charles J. Bieberich, Robert B. Jenkins, Fusheng Lan, Jessica L. Hicks, Bin Guan, Xiang Li, Dennis Faith, Carlise R. Bethel
Supplementary Results and Figure Legends 1-2 from Decreased NKX3.1 Protein Expression in Focal Prostatic Atrophy, Prostatic Intraepithelial Neoplasia, and Adenocarcinoma: Association with Gleason Score and Chromosome 8p Deletion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b962c3feded17cb751c0065350bdff95
https://doi.org/10.1158/0008-5472.22367010.v1
https://doi.org/10.1158/0008-5472.22367010.v1
Autor:
Angelo M. De Marzo, Charles J. Bieberich, Robert B. Jenkins, Fusheng Lan, Jessica L. Hicks, Bin Guan, Xiang Li, Dennis Faith, Carlise R. Bethel
Supplementary Figure 2 from Decreased NKX3.1 Protein Expression in Focal Prostatic Atrophy, Prostatic Intraepithelial Neoplasia, and Adenocarcinoma: Association with Gleason Score and Chromosome 8p Deletion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c284f72372b51489148718eff587026
https://doi.org/10.1158/0008-5472.22367013.v1
https://doi.org/10.1158/0008-5472.22367013.v1
Autor:
Charles J. Bieberich, Angelo M. De Marzo, Srinivasan Yegnasubramanian, Peter S. Nelson, Michael S. Moubarek, Ibrahim Kulac, Lucas A. Horn, Daniella Bianchi-Frias, Jessica L. Hicks, Ryan P. McMullin, May Khalili, Laura N. Mutton, Gretchen K. Hubbard
Supplementary Figure 1 Morphology of PIN in B13-MYC mice. Supplementary Figure 2 Phenotypic analysis of PIN in a B13-MYC mouse (ventral lobe, 52 weeks old). Supplementary Figure 3 Additional phenotypic analysis of B-MYC/Pten mouse PIN (anterior lobe,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a07c8677f7c45ab0a0216f1045565a3
https://doi.org/10.1158/0008-5472.22410195
https://doi.org/10.1158/0008-5472.22410195
Autor:
Angelo M. De Marzo, Charles J. Bieberich, Robert B. Jenkins, Fusheng Lan, Jessica L. Hicks, Bin Guan, Xiang Li, Dennis Faith, Carlise R. Bethel
Supplementary Figure 1 from Decreased NKX3.1 Protein Expression in Focal Prostatic Atrophy, Prostatic Intraepithelial Neoplasia, and Adenocarcinoma: Association with Gleason Score and Chromosome 8p Deletion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f8f9c0c206d54487c525104e4eadc8
https://doi.org/10.1158/0008-5472.22367016.v1
https://doi.org/10.1158/0008-5472.22367016.v1