Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Charles I. White"'
Autor:
Sébastien Lageix, Miguel Hernandez, Maria E. Gallego, Jérémy Verbeke, Yannick Bidet, Sandrine Viala, Charles I. White
Publikováno v:
Plant Direct, Vol 8, Iss 10, Pp n/a-n/a (2024)
Abstract Sequence‐specific endonucleases have been key to the study of the mechanisms and control of DNA double‐strand break (DSB) repair and recombination, and the availability of CRISPR‐Cas nucleases over the last decade has driven rapid prog
Externí odkaz:
https://doaj.org/article/567f7f04186648038df50dde99001489
Publikováno v:
PLoS Genetics, Vol 18, Iss 8, p e1010322 (2022)
Ensuring balanced distribution of chromosomes in gametes, meiotic recombination is essential for fertility in most sexually reproducing organisms. The repair of the programmed DNA double strand breaks that initiate meiotic recombination requires two
Externí odkaz:
https://doaj.org/article/ef3fb380985446dcaa8458f6eaa2f96e
Autor:
Miguel Hernandez Sanchez-Rebato, Alida M Bouatta, Maria E Gallego, Charles I White, Olivier Da Ines
Publikováno v:
PLoS Genetics, Vol 17, Iss 5, p e1008919 (2021)
An essential component of the homologous recombination machinery in eukaryotes, the RAD54 protein is a member of the SWI2/SNF2 family of helicases with dsDNA-dependent ATPase, DNA translocase, DNA supercoiling and chromatin remodelling activities. It
Externí odkaz:
https://doaj.org/article/6d91ceedaaa244b980cd4eae8823c1cc
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183006 (2017)
The ploidy of eukaryote gametes must be halved to avoid doubling of numbers of chromosomes with each generation and this is carried out by meiosis, a specialized cell division in which a single chromosomal replication phase is followed by two success
Externí odkaz:
https://doaj.org/article/fb992687af894ff59d7d90ce382db328
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86220 (2014)
In striking contrast to animals, plants are able to develop and reproduce in the presence of significant levels of genome damage. This is seen clearly in both the viability of plants carrying knockouts for key recombination and DNA repair genes, whic
Externí odkaz:
https://doaj.org/article/d5dc20d42f5440a3b55eac48cc32005b
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2021, 22 (23), pp.13115. ⟨10.3390/ijms222313115⟩
International Journal of Molecular Sciences, MDPI, 2021, 22 (23), pp.13115. ⟨10.3390/ijms222313115⟩
International Journal of Molecular Sciences, Vol 22, Iss 13115, p 13115 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 13115
International Journal of Molecular Sciences, 2021, 22 (23), pp.13115. ⟨10.3390/ijms222313115⟩
International Journal of Molecular Sciences, MDPI, 2021, 22 (23), pp.13115. ⟨10.3390/ijms222313115⟩
International Journal of Molecular Sciences, Vol 22, Iss 13115, p 13115 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 13115
International audience; DNA entanglements and supercoiling arise frequently during normal DNA metabolism. DNA topoisomerases are highly conserved enzymes that resolve the topological problems that these structures create. Topoisomerase II (TOPII) rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3084df8b2626b9d4e57c943e2097969f
https://hal.science/hal-03466732
https://hal.science/hal-03466732
Publikováno v:
PLoS Genetics, Vol 9, Iss 11, p e1003971 (2013)
The repair of DNA double-strand breaks by recombination is key to the maintenance of genome integrity in all living organisms. Recombination can however generate mutations and chromosomal rearrangements, making the regulation and the choice of specif
Externí odkaz:
https://doaj.org/article/461882e57ac44ecba77ccbda6b48a359
Publikováno v:
Frontiers in Plant Science, Vol 4 (2013)
Failure to repair DNA double strand breaks (DSB) can lead to chromosomal rearrangements and eventually to cancer or cell death. Radiation and environmental pollutants induce DSB and this is of particular relevance to plants due to their sessile life
Externí odkaz:
https://doaj.org/article/17c154d88f754c97afbfaa12cb5c9f2e
Autor:
Olivier Da Ines, Fabienne Degroote, Chantal Goubely, Simon Amiard, Maria E Gallego, Charles I White
Publikováno v:
PLoS Genetics, Vol 9, Iss 9, p e1003787 (2013)
Recombination establishes the chiasmata that physically link pairs of homologous chromosomes in meiosis, ensuring their balanced segregation at the first meiotic division and generating genetic variation. The visible manifestation of genetic crossing
Externí odkaz:
https://doaj.org/article/67ea5cd026654de4a2992ba136f61adb
Autor:
Ángeles Gómez-Zambrano, David Latrasse, Steven E. Jacobsen, Thierry Pélissier, Amy Hesketh, Leticia López-González, Moussa Benhamed, Pierre Bourguet, Magdalena E. Potok, Olivier Mathieu, Magali Perez, Marie-Noëlle Pouch-Pélissier, Olivier Da Ines, Charles I. White
Publikováno v:
Genome Biology
Genome Biology, 2020, 21 (1), ⟨10.1186/s13059-020-02190-1⟩
Genome Biology, BioMed Central, 2020, 21 (1), ⟨10.1186/s13059-020-02190-1⟩
Genome Biology, BioMed Central, 2020, 21, ⟨10.1186/s13059-020-02190-1⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Genome Biology, 2020, 21 (1), ⟨10.1186/s13059-020-02190-1⟩
Genome Biology, BioMed Central, 2020, 21 (1), ⟨10.1186/s13059-020-02190-1⟩
Genome Biology, BioMed Central, 2020, 21, ⟨10.1186/s13059-020-02190-1⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Background Chromatin organizes DNA and regulates its transcriptional activity through epigenetic modifications. Heterochromatic regions of the genome are generally transcriptionally silent, while euchromatin is more prone to transcription. During DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479257e40fa10310495a3485c709d965
https://hal.science/hal-03374658/file/s13059-020-02190-1.pdf
https://hal.science/hal-03374658/file/s13059-020-02190-1.pdf