Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Charles I. Grove"'
Autor:
Ruocheng Yu, Philipp Heretsch, Kyriacos C. Nicolaou, Verena Fetz, Charles I. Grove, Monette Aujay, Christopher R. H. Hale, Joseph Sandoval, Abdelatif ElMarrouni, Mark Brönstrup, Julia Gavrilyuk, Kiran Kumar Pulukuri, Stephan Rigol
Publikováno v:
Journal of the American Chemical Society. 138:6550-6560
A series of Δ(12)-prostaglandin J3 (Δ(12)-PGJ3) analogues and derivatives were synthesized employing an array of synthetic strategies developed specifically to render them readily available for biological investigations. The synthesized compounds w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a785811f82468ba50a2660b3e49d5d28
https://doi.org/10.1021/jacs.6b02075
https://doi.org/10.1021/jacs.6b02075
Autor:
Philipp Heretsch, Kyriacos C. Nicolaou, Kiran Kumar Pulukuri, Stephan Rigol, Charles I. Grove, Christopher R. H. Hale, Abdelatif ElMarrouni, Ruocheng Yu
Publikováno v:
ChemInform. 47
The total synthesis of Δ(12) -prostaglandin J3 (Δ(12) -PGJ3 , 1), a reported leukemia stem cell ablator, through a number of strategies and tactics is described. The signature cross-conjugated dienone structural motif of 1 was forged by an aldol re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2d0ac0772087ca16144fd25e78d6442
https://doi.org/10.1002/chin.201645186
https://doi.org/10.1002/chin.201645186
Autor:
Kyriacos C. Nicolaou, Philipp Heretsch, Abdelatif ElMarrouni, Kiran Kumar Pulukuri, Charles I. Grove, Ruocheng Yu, Stephan Rigol, Christopher R. H. Hale
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 22(25)
The total synthesis of Δ(12) -prostaglandin J3 (Δ(12) -PGJ3 , 1), a reported leukemia stem cell ablator, through a number of strategies and tactics is described. The signature cross-conjugated dienone structural motif of 1 was forged by an aldol re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9cf33fe5d07859691a14cad4841bf8
https://pubmed.ncbi.nlm.nih.gov/27187634
https://pubmed.ncbi.nlm.nih.gov/27187634
Publikováno v:
Organic Letters. 14:4338-4341
Efficient and stereoselective syntheses of pigmentosin A, talaroderxine A, and its diastereomer talaroderxine B are reported. The binaphthyl ring system is assembled by vanadium-catalyzed phenolic coupling of tricyclic precursors. These key intermedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a1fe2c7f39903535e2f0f9d271c3ef6
https://doi.org/10.1021/ol301743t
https://doi.org/10.1021/ol301743t
Autor:
Sameer Urgaonkar, Young Sam Park, Marcos González-López, James C. Fettinger, Jared T. Shaw, Charles I. Grove
Publikováno v:
Angewandte Chemie International Edition. 50:3730-3733
The inhibition of bacterial cell division offers a new approach to controlling resistant bacterial infections.[1, 2] FtsZ is a protein of central importance to cell division that is often described as the prokaryotic homolog of tubulin because of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19700fa18c6cc2c92ed244aca5904060
https://doi.org/10.1002/anie.201007298
https://doi.org/10.1002/anie.201007298
Efficient and enantioselective syntheses of a family of 6,6′-binaphthopyranone natural products (viriditoxin, pigmentosin A, talaroderxine A, and talaroderxine B) are reported. A vanadium-catalyzed oxidative coupling provides the key axial chiralit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de1ad5a4b04cb3d697b618bd47da3e70
https://doi.org/10.1016/b978-0-12-417185-5.00010-7
https://doi.org/10.1016/b978-0-12-417185-5.00010-7
Autor:
Michelle B. Kim, Laura L. Lackner, Terrence E. O’Brien, David E. Anderson, Jared T. Shaw, Charles I. Grove, Jared T. Moore, Nohemy A. Sorto, James B. Ames
FtsZ is a guanosine triphosphatase (GTPase) that mediates cytokinesis in bacteria. FtsZ is homologous in structure to eukaryotic tubulin and polymerizes in a similar head-to-tail fashion. The study of tubulin's function in eukaryotic cells has benefi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::571af2593485dbfe36707b144cb4638a
https://europepmc.org/articles/PMC3514448/
https://europepmc.org/articles/PMC3514448/