Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Charles Humfrey"'
Publikováno v:
Haematologica, Vol 102, Iss 2 (2017)
Externí odkaz:
https://doaj.org/article/917f9aad6ca54570b29686c0c3ed1972
Publikováno v:
ALTEX.
Hazard assessments of skin sensitizers are increasingly being performed using new approach methodologies (NAMs), with several in chemico, in vitro and most recently also defined approaches (DAs) being accepted for regulatory use. However, keeping tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a244c35a54f63f5c9532a5bbcfcfa1a
https://doi.org/10.14573/altex.2201281
https://doi.org/10.14573/altex.2201281
Autor:
Steve Warrington, Christina Keen, Charles Humfrey, Mohib Uddin, Bengt Larsson, Stipo Jurcevic
Publikováno v:
British Journal of Clinical Pharmacology. 80:1324-1336
AIMS: The aim of the present study was to investigate whether selective antagonism of the cysteine-X-cysteine chemokine receptor-2 (CXCR2) receptor has any adverse effects on the key innate effector functions of human neutrophils for defence against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2d8efda0eaa4d829b9d60bd2ccf578d
https://doi.org/10.1111/bcp.12724
https://doi.org/10.1111/bcp.12724
Controlled trafficking of neutrophils is an important component of the host innate immunity.[1][1] Neutrophils express a number of chemokine receptors, CXCR2 among them, which, following activation by its cognate chemokines CXCL1 and CXCL8, become mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbaeb47000aadb7921e62eb1550aeeb
https://europepmc.org/articles/PMC5286957/
https://europepmc.org/articles/PMC5286957/
Autor:
Charles Humfrey
Publikováno v:
Asian Affairs. 41:10-19
The article considers Indonesia's democratic advance over the last five years, effectively the first term in office of President Yudhoyono. Focussing on the three threats which seemed most acute in 2004 - Fragmentation, Macroeconomic Instability and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33318eab7444ba61fa72c9a61e7dfe72
https://doi.org/10.1080/03068370903472041
https://doi.org/10.1080/03068370903472041
Autor:
Charles Humfrey
Publikováno v:
Toxicological Sciences. 100:24-28
Controlling the quality of medicines is just as important as demonstrating efficacy. The International Conference on Harmonisation has published general guidance on the quality and safety assessment of impurities in pharmaceutical drug substances and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd579d8a4fb2f7faec8148847b4e4593
https://doi.org/10.1093/toxsci/kfm173
https://doi.org/10.1093/toxsci/kfm173
Autor:
Charles Humfrey
Publikováno v:
Asian Affairs. 44:321-323
Anthony Reid (ed). Indonesia Rising: The Repositioning of Asia's Third Giant. ISEAS, Singapore, 2012. pp. xxiv + 198. Boxes. Tables. Figs. Notes. Refs. Index. Pb. $20.90. ISBN 9 7898 1438 0393 Indo...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::507c05518dff8a7d9b30fec686fabca7
https://doi.org/10.1080/03068374.2013.795375
https://doi.org/10.1080/03068374.2013.795375
Autor:
Charles Humfrey, Andrew Teasdale
Publikováno v:
Genotoxic Impurities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e9c408e24b4990d921cb48bb6647179
https://doi.org/10.1002/9780470929377.ch5
https://doi.org/10.1002/9780470929377.ch5
Autor:
Rebecca Frank, Lutz Müller, Larry P. Yotti, Mark D. Smith, Robert J. Mauthe, Jane A. Fagerland, Ganapathy Mohan, Nirdosh Jagota, Chris Beels, Alexander S. Jacks, Joseph J. DeGeorge, Dean Ellison, John MacKinnon, Sheila M. Galloway, Charles Humfrey, Marta M. Andino, Michael R. O’Donovan, Betsy Fritschel, Daniel K. Ness, Alfons G.M. De Knaep, Christopher M. Riley, Ernie Harpur, Gopi Vudathala, David M. De Antonis
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 44(3)
The synthesis of pharmaceutical products frequently involves the use of reactive reagents and the formation of intermediates and by-products. Low levels of some of these may be present in the final drug substance and drug product as impurities. Such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e722b60284f601580faa4280e53224
https://pubmed.ncbi.nlm.nih.gov/16412543
https://pubmed.ncbi.nlm.nih.gov/16412543
Autor:
Charles Humfrey, Matthew Jacobsen
Publikováno v:
Toxicology Letters. 229:S204
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a44d0b53e6d52a212ab6ed3ef6422446
https://doi.org/10.1016/j.toxlet.2014.06.687
https://doi.org/10.1016/j.toxlet.2014.06.687